Rafael J. Pascual
A5073441427- Medieval Literature and History
- Linguistics and language evolution
- HIV/AIDS Research and Interventions
- HIV/AIDS drug development and treatment
- HIV Research and Treatment
- Linguistic Variation and Morphology
- Pneumocystis jirovecii pneumonia detection and treatment
- Lexicography and Language Studies
- Historical Linguistics and Language Studies
- Libraries, Manuscripts, and Books
- HIV-related health complications and treatments
- Multicultural Socio-Legal Studies
- Treatment of Major Depression
- Historical and Religious Studies of Rome
- Adrenal Hormones and Disorders
- Obsessive-Compulsive Spectrum Disorders
- Psychology Research and Bibliometrics
- Medieval European Literature and History
- Historical, Literary, and Cultural Studies
- Historical Studies of British Isles
- Themes in Literature Analysis
- Health and Lifestyle Studies
- Translation Studies and Practices
- Data Mining Algorithms and Applications
- Opioid Use Disorder Treatment
Universidad de Granada
2014-2024
University of Oxford
2018-2024
Unidad de Investigación en cuidados y servicios de salud (Investén-isciii)
2022
Instituto de Salud Carlos III
2022
Centro de Investigación Biomédica en Red
2022
Hospital General Universitario de Elche
2022
New College
2020
St. Catherine University
2019
University of Alicante
2017
Harvard University Press
2015-2017
Abstract Objectives To assess the effectiveness and tolerability of dolutegravir (DTG)/lamivudine (3TC) among treatment-naive virologically suppressed treatment-experienced individuals in multicentre cohort Spanish HIV/AIDS Research Network (CoRIS) during years 2018–2021. Methods We used multivariable regression models to compare viral suppression (VS) [HIV RNA load (VL) <50 copies/mL] change CD4 cell counts at 24 48 (±12) weeks after initiation with dolutegravir/lamivudine or other...
BackgroundWhile a low CD4/CD8 ratio during HIV treatment correlates with immunosenescence, its value in identifying patients at an increased risk for clinical events remains unclear.MethodsWe analyzed data from the CoRIS cohort to determine whether CD4 count, CD8 and year two of antiretroviral therapy (ART) could predict serious non-AIDS (SNAEs) next five years. These included major adverse cardiovascular events, non-AIDS-defining malignancies, non-accidental deaths. We used pooled logistic...
According to Hrothgar’s account of Grendel’s mere, every night one can see there fȳr on flōde, a phrase often translated as ‘fire the water’. This fire, which king describes nīðwundor (a dreadful wonder), has traditionally been seen by scholars supernatural phenomenon that contributes presentation place eerie. Geoffrey Russom and Christopher Abram have taken an alternative view: they argue means in/within water’ interpret it in two different ways. believes mere is entrance hell, flōde refers...
Middle English verse of the so-called Alliterative Revival evinces a pattern alliteration across line and series rhythmical configurations within half-line that are reminiscent t...
A. J. Bliss, in his authoritative and influential monograph on The Metre of Beowulf (1967), analysed l. 1563a, hē ġefēng þā fetelhilt, as a member group (4) verses beginning with finite verbs. In that group, which the verb is last particle before first stressed element, alliterating verbs are thought to be an integral part alliterative scheme line hence metrically stressed. This means that, according 1563a Type 1A2a ġe- anacrusis. analysis compatible Bliss’s definition anacrusis, any two...
PURPOSE: To compare personality profiles of internal medicine residents with those the general population and positive role models in medicine. METHOD: A widely used inventory, NEO PI-R, which measures five major factors 30 important facets, was administered 1998 to 104 physicians residency earlier a nationwide sample 188 selected as RESULTS: The residents, compared population, were more likely be attentive, have deeper intellectual curiosity, higher aspiration levels, vivid imaginations,...
A decade ago, Thomas A. Bredehoft designed a new theory of Old English metre that classified Ælfric Eynsham's rhythmical-alliterative texts as verse. The present article submits Bredehoft's metrical to critical scrutiny by means three case studies. first deals with for simplicity in argumentation; the second assesses theoretical validity exclusively syllabic substitute traditional four-position principle; and third focuses on system late its application Ælfric's texts. These studies...
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This article undertakes the first systematic examination of Frank’s (1979, 1981, 1987, 1990, 2007b, 2008) claim that Old Norse influence is discernible in language Beowulf . It tests this hypothesis by scrutinizing each alleged Nordicisms , then discussing various theoretical considerations bearing on its plausibility. We demonstrate syntactic, morphological, lexical, and semantic peculiarities Frank would explain as manifestations are more economically holistically explained consequences...
Because of its faulty alliteration and irregular metrical configuration, the manuscript reading felasinniġne secg, corresponding to l. 1379a Beowulf, has traditionally been emended sinniġne secg by most editors poem, who have thus regarded fela as a scribal interpolation. As Klaeber IV suggested, rationale behind such an interpolation probably is that scribe mistook 1378b, ðǣr þū findan miht, verse pair, thereby introducing in order remedy lack f alliteration. This credible hypothesis, since...
To assess the attitudes and opinions about generic antiretroviral drugs (ARVs) single-tablet regimen (STR) de-simplification among physicians prescribing HIV treatment in cohort of Spanish HIV/AIDS Research Network (CoRIS).An online questionnaire with 27 structured questions was sent to all (n=199) who prescribed ARVs 45 centres participating cohort.A total 169 (84.9%) answered questionnaire. Only 4.1% would never prescribe ARVs, but 53.3% not them if number pills per day increased 89.3%...
Abstract Objectives We compared 48 week effectiveness and safety of first-line antiretroviral regimens. Methods analysed HIV treatment-naive adults from the Cohort Spanish HIV/AIDS Research Network (CoRIS) starting most commonly used regimens 2014 to 2018. multivariable regression models assess impact initial regimen on: (i) viral suppression (VS) (viral load <50 copies/mL); (ii) change in CD4 cell count; (iii) CD4/CD8 normalization (>0.4 >1); (iv) percentage...
In an iconoclastic essay published in 2003, Thomas A. Bredehoft contended that Old English dithematic names are prosodically identical to compound words despite the existence of compelling evidence contrary. He founded his analysis on allegedly overlooked afforded by participation non-primary patterns alliteration Beowulf and their manuscript presentation. Moreover, because traditional notion compounds have different prosodic configurations is a large extent based furnished Eduard Sievers’s...
The present study sought to describe the use of generic drugs and single-tablet regimen (STR) de-simplification for treatment human immunodeficiency virus (HIV) infection among 41 hospitals from cohort Spanish HIV/AIDS Research Network (CoRIS). In June 2018, we collected information on when antiretroviral (ARVs) were introduced in different hospitals, how decisions them made, was provided patients. Most nine available ARVs Spain by 2018 had been at least 85% participating except zidovudine...
Old English poetry is characterized by its varying and unpredictable number of syllables per verse.In Beowulf, 1 for example, tetrasyllabic verses like l. 42a, on flōdes ǣht, are very frequent, but one can also find 1189b, ond haeleþa bearn, 1954b, wið brego, which respectively consist five six syllables.This peculiar feature puzzled early scholars poetry, who found themselves unable to come up with a coherent explanation such bewildering array syllabic sequences.At the end nineteenth...
Abstract Acquired immunodeficiency syndrome (AIDS) is still one of the main health problems worldwide. It therefore essential to keep making progress in improving prognosis and quality life affected patients. One way advance along this pathway uncover connections between other disorders associated with HIV/AIDS—so that they can be anticipated possibly mitigated. We propose achieve by using Association Rules (ARs). They allow us represent dependencies a number diseases specific diseases....
Book review of Tolkien, J. R. 2023. The Battle Maldon Together with the Homecoming Beorhtnoth. Edited by Peter Grybauskas. London: Harper Collins. Pp. 188. ISBN 9780008465827.