A5102994381- Dementia and Cognitive Impairment Research
- Older Adults Driving Studies
- Urban Transport and Accessibility
- Geriatric Care and Nursing Homes
- Family Caregiving in Mental Illness
- Traffic and Road Safety
- Language Development and Disorders
- Epilepsy research and treatment
- Autism Spectrum Disorder Research
- Intergenerational Family Dynamics and Caregiving
- Pharmaceutical Practices and Patient Outcomes
- Infant Health and Development
- Infant Development and Preterm Care
- Human-Automation Interaction and Safety
- Psychosomatic Disorders and Their Treatments
- Neurological disorders and treatments
- Stroke Rehabilitation and Recovery
- Thyroid Disorders and Treatments
- Frailty in Older Adults
- Cognitive Functions and Memory
- Intensive Care Unit Cognitive Disorders
- Pharmacological Effects and Toxicity Studies
- Medication Adherence and Compliance
- Health and Wellbeing Research
- Health disparities and outcomes
Brown University
2016-2025
Arizona State University
2019-2025
Rhode Island Hospital
2015-2024
Providence College
2014-2024
Lifespan
2004-2024
Google (United States)
2021-2022
National University of Singapore
2019
John Brown University
2019
Kelowna General Hospital
2018
Florida International University
2013
<h3>Objective:</h3> Age at onset of diagnostic motor manifestations in Huntington disease (HD) is strongly correlated with an expanded CAG trinucleotide repeat. The length the normal repeat allele has been reported also to influence age onset, interaction allele. Due profound implications for mechanism and modification, we tested whether allele, between alleles, or presence a second affects HD signs. <h3>Methods:</h3> We modeled natural log-transformed as function lengths alleles their by...
BackgroundMost US troops returned home from the Persian Gulf War (PGW) by Spring 1991 and many began reporting increased health symptoms medical problems soon after. This investigation examines relationships between several Gulf-service environmental exposures symptom reporting, role of traumatic psychological stress on exposure-health relationships.
Dementia caregiver appraisal of the quality their current and premorbid relationship with care recipient is associated caregiving behaviors, mood, decision to end home care. This study examined contribution satisfaction burden in dementia caregivers. Live-in caregivers (n = 72) completed several psychosocial measures. Caregiver responses were used divide them into low group (low) versus high (high). Results indicate that negatively family functioning. Caregivers demonstrated significantly...
<b>Objective: </b> The goal of this study was to define the natural progression driving impairment in persons who initially have very mild dementia. <b>Methods: We studied 128 older drivers, including 84 with early Alzheimer disease (AD) and 44 age-matched control subjects without cognitive impairment. Subjects underwent repeated assessments their cognitive, neurologic, visual, physical function over 3 years. Self-reports accidents traffic violations were supplemented by reports from family...
Identifying effective and accessible interventions for dementia caregivers is critical as prevalence increases. Examine the effects of a telephone-based intervention on caregiver well-being. Randomized, controlled trial. Academic medical center. Two hundred fifty distressed, family, caregivers. Caregivers randomized to receive 16 telephone contacts over 6 months either Family Intervention: Telephone Tracking-Caregiver (FITT-C) or Support (TS). Primary outcome variables were family...
The objective of this study was to examine the preliminary efficacy Family Intervention: Telephone Tracking — Dementia (FITT-D), a multi-component intervention that is delivered in 23 telephone contacts over 12 months. Thirty-three dementia caregivers were randomly assigned receive either FITT-D ( n = 16) or standard care 17) using urn randomization balance groups on severity, caregiver gender and relationship type (spouse versus other). Inclusion criteria included formal diagnosis,...
Several factors influence dementia caregiver desire to institutionalize; however, little is known about differences in caregivers who institutionalization versus those do not. The current study compares predictors of institutionalize caregivers. Seventy-two completed the Desire Institutionalize Scale (DIS) and several psychosocial measures, including burden, knowledge, self-efficacy, depression, health, care recipient daily functioning memory/behavior problems, family functioning, social...
Cognitive deficits are common in epilepsy, though the impact of epilepsy on cognition older adults is understudied. This study aimed to characterize with compared healthy and identify potential risk factors for impairment. Thirty-eight 29 controls completed a comprehensive neuropsychological battery, as well measures depression anxiety. Chart review current medications, seizure history, neuroimaging was also completed. To compare cognitive performance between groups, ANOVA used, linear...
Summary Purpose: To evaluate different contributions of aspects family functioning (FF) on health‐related quality life (HRQOL) in patients with psychogenic nonepileptic seizures (PNES) versus epileptic (ES). Methods: Forty‐five participants PNES and 32 ES completed self‐report measures FF (Family Assessment Device; FAD), HRQOL (Quality Life Epilepsy‐31), depression (Beck Depression Inventory‐II; BDI‐II). The FAD is a questionnaire that assesses along six dimensions general functioning....
To examine the sensitivity and specificity of Assessment Driving-Related Skills (ADReS), a clinical tool recommended by American Medical Association for identifying potentially unsafe older drivers that includes tests vision, motor function, cognition. Cross-sectional observation study. Memory assessment outpatient clinic university hospital. Drivers with normal cognition (n = 47) cognitive impairment 75). A neurologist completed ADReS during an office visit. Additional executive,...
Objective: Previous literature has examined burden and depression predominately as unitary constructs in relation to dementia caregiving. No studies thus far have gender differences the specific components of caregivers. The current study whether empirically validated dimensions caregiver differed by for caregivers.Methods: sample consisted 211 caregivers enrolled a longitudinal intervention study. Only baseline functioning was evaluated this Levels were assessed using Zarit Burden Interview...
To assess the clinical utility of Trail-Making Tests (TMTs) as screens for impaired road-test performance. Secondary analyses three data sets from previously published studies driving in older adults using comparable road test designs and outcome measures. Two academic specialty clinics. Older drivers (N = 392; 303 with cognitive impairment, 89 controls) Rhode Island Missouri. Standard operating characteristics were evaluated TMT Part A (TMT-A) B (TMT-B), well optimal upper lower cut-points...
Behavioral problems in the dementia patient are some of strongest predictors caregiver burden, though impact specific types behavioral on burden is limited. This study investigated contribution frontal systems functioning (i.e., apathy, executive dysfunction, and disinhibition) burden. Seventy-two family caregivers completed Frontal Systems Behavior Scale measures mood, perceived ratings functional impairment. Regression analyses indicated that were predictive after controlling for severity...
This study examined the ability of computerized maze test performance to predict road cognitively impaired and normal older drivers. The authors 133 drivers, including 65 with probable Alzheimer disease, 23 possible 45 control subjects without cognitive impairment. Subjects completed 5 tasks employing a touch screen pointer as well battery standard neuropsychological tests. Parameters measured for mazes included errors, planning time, drawing total time. Within 2 weeks, were by professional...
Objectives To relate the standardized road test to video recordings of naturalistic driving in older adults with a range cognitive impairment. Design Cross‐sectional observational study. Setting Academic medical center memory disorders clinic. Participants One hundred three drivers (44 healthy, 59 impairment) who passed test. Measurements Error rate and global ratings safety (pass without recommendations, marginal restrictions or training, fail) made by professional instructor. Results There...
Background: Emerging evidence shows that cognitively normal older adults with preclinical Alzheimer’s disease (AD) make more errors and are likely to receive a marginal/fail rating on standardized road test compared without AD, but the extent which AD impacts everyday driving behavior is unknown. Objective: To examine self-reported naturalistic longitudinal among persons AD. Method: We prospectively followed drivers (aged 65 + years) ( n = 10) for 2.5 years. Preclinical was assessed using...
Objective: Older adults with cognitive impairment are at risk of medication-taking errors. This study assessed the impact providing medication adherence feedback to cognitively impaired older adults. Methods: Forty participants mild or dementia had their electronically monitored for 8 weeks. They were provided verbal and visual about results. Initial participant reactions elicited using a Motivational Interviewing approach, self-reported behavior changes during follow-up interview....
Purpose: Down syndrome (DS) is associated with lifelong difficulties verbal communication, beginning in infancy when vocalizations are sparse and first words emerge late. Because DS diagnosed at or even before birth, these can be anticipated, yet there have been limited developments of systematic, proactive interventions. The purpose the pilot study described here was to investigate feasibility potential benefits such an intervention toward a fully powered clinical trial. Method: We piloted...
The role of actual or perceived events has considerable importance for individual well-being. Although the Persian Gulf War (PGW) raised questions about presence hazardous environmental exposures, few, if any confirmed exposure data are available. Yet, a substantial number PGW veterans report health problems since their return from that war. present study was conducted to investigate possible associations between opportunities and increased rates symptom reporting. First, we examined...
The relationship between family functioning and dementia caregiving is complex. present study examined the interrelationships functioning, caregiver burden, patient characteristics. Participants were 72 live-in, caregivers of patients with mild (n = 47) or moderate 25). Caregivers completed measures depression, anxiety. Ratings patients' memory/behavior problems activities daily living also collected. Results indicated that higher levels burden significantly associated increased depression...
Dementia caregivers often report feeling burdened by caretaking responsibilities. Caregiver burden is correlated with caregiver depression, but the interrelationship between and depression requires further investigation. This study hypothesized that persisting elevated results in subsequent depressive symptoms. Participants were 33 dementia divided into two groups based on their Zarit Burden Interview score. The outcome variable was total score Geriatric Depression Scale after 12 months....
Study the preliminary efficacy of a telephone intervention, Family Intervention: Telephone Tracking-Nursing Home (FITT-NH) for improving dementia caregivers' adjustment following nursing home placement.Caregivers were enrolled on average 6 weeks care-recipients' placement in home. Baseline assessment included self-report measures caregiver emotional functioning, staff-caregiver interactions, satisfaction, health-related quality life, and social support. Caregivers randomly assigned to...