Erik B. Beall
- Advanced MRI Techniques and Applications
- Functional Brain Connectivity Studies
- Advanced Neuroimaging Techniques and Applications
- Astrophysics and Cosmic Phenomena
- Neutrino Physics Research
- Multiple Sclerosis Research Studies
- Particle physics theoretical and experimental studies
- Transcranial Magnetic Stimulation Studies
- Neurological disorders and treatments
- Parkinson's Disease Mechanisms and Treatments
- Bipolar Disorder and Treatment
- Atomic and Subatomic Physics Research
- Infrared Thermography in Medicine
- Stroke Rehabilitation and Recovery
- Mental Health Research Topics
- Dark Matter and Cosmic Phenomena
- Traumatic Brain Injury and Neurovascular Disturbances
- Traumatic Brain Injury Research
- Thermal Regulation in Medicine
- Thermoregulation and physiological responses
- Muscle activation and electromyography studies
- Advanced NMR Techniques and Applications
- Cardiac Arrest and Resuscitation
- Treatment of Major Depression
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Cleveland Clinic
2011-2023
Lou Ruvo Brain Institute
2016
Imaging Center
2011-2013
Siemens (United States)
2011
University of Minnesota System
2007-2008
Argonne National Laboratory
2006-2008
University of Minnesota
2005-2008
This Letter reports results from the MINOS experiment based on its initial exposure to neutrinos Fermilab NuMI beam. The rates and energy spectra of charged current ${\ensuremath{\nu}}_{\ensuremath{\mu}}$ interactions are compared in two detectors located along beam axis at distances 1 735 km. With $1.27\ifmmode\times\else\texttimes\fi{}{10}^{20}$ 120 GeV protons incident target, 215 events with energies below 30 observed Far Detector, an expectation $336\ifmmode\pm\else\textpm\fi{}14$...
<h3>Objective:</h3> Age at onset of diagnostic motor manifestations in Huntington disease (HD) is strongly correlated with an expanded CAG trinucleotide repeat. The length the normal repeat allele has been reported also to influence age onset, interaction allele. Due profound implications for mechanism and modification, we tested whether allele, between alleles, or presence a second affects HD signs. <h3>Methods:</h3> We modeled natural log-transformed as function lengths alleles their by...
Abstract Recent studies indicate that functional connectivity using low‐frequency BOLD fluctuations (LFBFs) is reduced between the bilateral primary sensorimotor regions in multiple sclerosis. In addition, it has been shown pathway‐dependent measures of transverse diffusivity water white matter correlate with related clinical deficit Taken together, these methods suggest MRI can be used to probe both and anatomic subjects known impairment. We report results a study comparing transcallosal...
We report the results of a search for ${\ensuremath{\nu}}_{\ensuremath{\mu}}$ disappearance by Main Injector Neutrino Oscillation Search [D. G. Michael et al. (MINOS), Phys. Rev. Lett. 97, 191801 (2006).]. The experiment uses two detectors separated 734 km to observe beam neutrinos created Neutrinos at facility Fermi National Accelerator Laboratory. data were collected in first 282 days operations and correspond an exposure $1.27\ifmmode\times\else\texttimes\fi{}{10}^{20}$ protons on target....
The velocity of a ∼3 GeV neutrino beam is measured by comparing detection times at the near and far detectors MINOS experiment, separated 734 km. A total 473 detector events was used to measure (v−c)/c=5.1±2.9×10−5 (at 68% C.L.). By correlating energies 258 charged-current their arrival detector, limit imposed on mass mν<50 MeV/c2 (99% C.L.).Received 4 June 2007DOI:https://doi.org/10.1103/PhysRevD.76.072005©2007 American Physical Society
Military personnel involved in Operations Enduring Freedom and Iraqi (OEF/OIF) commonly experience blast-induced mild to moderate traumatic brain injury (TBI). In this study, we used task-activated functional MRI (fMRI) determine if blast-related TBI has a differential impact on activation comparison with caused primarily by mechanical forces civilian settings. Four groups participated: (1) military (milTBI; n=21); (2) controls (milCON; n=22); (3) non-blast (civTBI; (4) (civCON; n=23)...
Bipolar disorder (BP) is characterized by periods of depression (BPD) and (hypo)mania (BPM), but the underlying state-related brain circuit abnormalities are not fully understood. Striatal functional activation connectivity have been noted in BP, consistent findings reported. To further elucidate striatal different BP states, this study investigated differences resting-state six subregions BPD, BPM, healthy control (HC) subjects. Ninety medication-free subjects (30 30 HC), closely matched...
Forced-rate lower-extremity exercise has recently emerged as a potential safe and low-cost therapy for Parkinson's disease (PD). The efficacy is believed to be dependent on pedaling rate, with rates above the subjects' voluntary being most beneficial. In this study, we use functional connectivity magnetic resonance imaging (MRI) further elucidate mechanism underlying effect. Twenty-seven PD patients were randomized complete 8 weeks of forced-rate (FE) or voluntary-rate (VE). Exercise was...
Parkinson's disease (PD) is a progressive neurologic disorder primarily characterized by an altered motor function. Lower extremity forced exercise (FE) has been shown to reduce symptoms in patients with PD. Recent functional magnetic resonance imaging (fMRI) studies have that FE and medication produce similar changes brain activation patterns. Functional connectivity MRI (fcMRI) affords the ability look at how strongly nodes of circuit communicate each other can provide insight into...
Past neuroimaging work has suggested that increased activation to cognitive and emotional tasks decreased connectivity in frontal regions are related inefficiency depression; normalization of these relationships been associated with successful treatment. The present study investigated brain function before after electroconvulsive therapy (ECT) patients major depressive disorder (MDD) demonstrated the effect treatment on cortical patterns.Six ECT-naive depression (mean ± SD age, 39.0 5.4...
The pain matrix is comprised of an extensive network brain structures involved in sensory and/or affective information processing.The thalamus a key structure constituting the matrix.The serves as relay center receiving from multiple ascending pathways and relating to cortical areas.However, it unknown how thalamocortical networks specific sensory-affective processing are functionally integrated.Here, proof-of-concept study healthy humans, we aimed understand this connectivity using...
The 5.4 kton MINOS far detector has been taking charge-separated cosmic ray muon data since the beginning of August, 2003 at a depth 2070 m.w.e. in Soudan Underground Laboratory, Minnesota, USA. with both forward and reversed magnetic field running configurations were combined to minimize systematic errors determination underground charge ratio. When averaged, two independent analyses find ratio be...
The complete 5.4 kton MINOS far detector has been taking data since the beginning of August 2003 at a depth 2070 meters water-equivalent in Soudan mine, Minnesota. This paper presents first observations muon neutrino and anti-neutrino charged-current atmospheric interactions based on an exposure 418 days. ratio upward to downward-going events is compared Monte Carlo expectation absence oscillations giving: R_data(up/down)/R_MC(up/down) = 0.62^{+0.19}_{-0.14} (stat.) +- 0.02 (sys.). An...
Progression of migraine toward a more disabling chronic form at least 15 days/month is linked with frequency attacks. Magnetic resonance imaging (MRI) findings iron accumulation in the brain, especially periaqueductal gray and red nucleus, have been correlated both duration illness attacks.This study therefore evaluated deposition as measured MRI basal ganglia pain regulatory nuclei neurologically healthy control volunteers patients various subtypes: episodic (n = 10) 4) or without aura 6),...
Background: Imaging can provide noninvasive neural markers of disease progression in multiple sclerosis (MS) that are related to behavioral and cognitive symptoms. Past work suggests diffusion tensor imaging (DTI) provides a measure white matter pathology, including demyelination axonal counts. Objectives: In the current study, authors investigate relationship DTI measures cingulum bundle common deficits MS, episodic memory, working information processing speed. Methods: Fifty-seven patients...
Mild to moderate traumatic brain injury (TBI) due blast exposure is frequently diagnosed in veterans returning from the wars Iraq and Afghanistan. However, it unclear whether neural damage resulting TBI differs that found blunt-force trauma (e.g., falls motor vehicle crashes). Little also known about effects of on networks, particularly over long term. Because impairment working memory has been linked TBI, present functional magnetic resonance imaging (fMRI) study sought investigate...
Transcranial direct current stimulation (tDCS) targeting the primary motor cortex is modestly effective for promoting upper-limb function following stroke. The premotor (PMC) represents an alternative target based on its higher likelihood of survival and dense motor-network connections.