A5086041403- Nail Diseases and Treatments
- RNA Research and Splicing
- Dermatology and Skin Diseases
- Cytokine Signaling Pathways and Interactions
- Body Image and Dysmorphia Studies
- Psoriasis: Treatment and Pathogenesis
- Cell Adhesion Molecules Research
- Neuroendocrine regulation and behavior
- Empathy and Medical Education
- Cutaneous lymphoproliferative disorders research
- Plant Pathogens and Fungal Diseases
- Antifungal resistance and susceptibility
- Allergic Rhinitis and Sensitization
- Skin and Cellular Biology Research
- Monoclonal and Polyclonal Antibodies Research
- Tattoo and Body Piercing Complications
- Complementary and Alternative Medicine Studies
- Fungal Infections and Studies
- Gut microbiota and health
- RNA regulation and disease
- Neuropeptides and Animal Physiology
- Bee Products Chemical Analysis
- Fungal Biology and Applications
- Food Industry and Aquatic Biology
- Virus-based gene therapy research
Semmelweis University
2024
Roswell Park Comprehensive Cancer Center
2024
University of Pecs
2017-2023
Hungarian Academy of Sciences
2014-2019
University of Szeged
2014-2018
HUN-REN Szegedi Biológiai Kutatóközpont
2015
Institute of Biochemistry
2015
Creative Research Enterprises (United States)
2014
Two bolt-on dimensions (skin irritation, self-confidence) have been developed for the EQ-5D-5L to improve its content validity and responsiveness in psoriasis. However, two bolt-ons are not strictly psoriasis-specific potentially relevant other skin conditions. This study aims explore of with patients atopic dermatitis (AD).
There is an increasing number of evidence showing analgesic properties the kynurenic acid (KYNA), and also some studies demonstrate that kynurenine might interact with opioid system. Therefore in this study, for first time we investigated direct binding affinity KYNA its structural analog KYNA-1 towards mu, kappa delta receptor competition experiments applying specific radioligands. The measurements were performed Chinese hamster ovary cell lines overexpressing corresponding (mu rat, mouse...
Parkinson’s disease (PD) is a common neurodegenerative disorder characterized by bradykinesia, resting tremor, and muscle rigidity. To date, approximately 50 genes have been implicated in PD pathogenesis, including both Mendelian with rare mutations low-penetrance polymorphisms. Previous studies of focused on protein-coding genes, less attention was given to long noncoding RNAs (lncRNAs). In this study, we aimed investigate the susceptibility roles lncRNA gene polymorphisms development PD....
Psychodermatology is an evolving interdisciplinary scientific field that explores the relationship between skin, nervous system, and psychological phenomena. Investigation of factors’s role in pathogenesis, course, prognosis, treatment certain dermatological conditions based on modern psychosomatic biopsychosocial disease model . Despite increasing acceptance psychodermatology extensive research field, role, position, competencies, practices involved psychodermatological care remain...
Hemopressin, so-called because of its hypotensive effect, belongs to the derivatives hemoglobin α-chain. It was isolated from rat brain membrane homogenate by use catalytically inactive forms endopeptidase 24.15 and neurolysin. Hemopressin has antihyperalgesic features that cannot be prevented opioid receptor antagonist, naloxone.In present study, we investigated whether hemopressin (PVNFKFLSH) C-terminally truncated fragment 1-7 (PVNFKFL) have any influence on opioid-dependent signaling....
In our recent cDNA microarray experiment, three SR-rich splicing factors-SFRS18, PPIG and LUC7L3-were shown to exert altered responsiveness upon T-lymphokine stimulation of psoriatic non-involved healthy epidermis samples. We have also demonstrated that double silencing LUC7L3 SFRS18 efficiently decreased production the psoriasis-associated EDA+ fibronectin isoform. These findings prompted further investigation signalling pathways affected by SFRS18. To detect gene expression pattern...
Tinea corporis and congenital ichthyoses are common dermatological diseases. The association of the two disorders is plausible due to immunological barrier defects ichthyoses; however, relatively limited literature available in this field. Since superficial fungal infections possess atypical morphology keratinization disorders, could imitate other conditions, correct diagnosis can be challenging. We present case a 54-year-old woman with ichthyosis, who was initially treated for...
Psoriasis is a chronic immune-mediated inflammatory disease that can often be associated with psychiatric problems such as depression and anxiety. Although disorders were initially considered secondary, their high prevalence suggests common pathophysiological mechanisms may involved in the development of psoriasis certain disorders. Moreover, psychological treatments not only improve quality life, but also alleviate symptoms. This article highlights psychodermatological aspects psoriasis,...
Tattooing is a widespread phenomenon, however lot of people have negative attitude tattoos The current literature highlight the strong psychological components behind motivations tattooing. . Motifs on body may be associated with personality disorders, dysmorphic disorder (BDD), addictions or self-destructive behaviour. On other hand, tattooing could help psychosocial coping certain traumas. In dermatological patient high number important to examine patient’sfrom point view potential...
A wide range of topical and systemic products are now available for the treatment mycotic skin infections. T he choice an appropriate therapy requires reliable microbiological diagnostics knowledge exact mechanism action side effects antimycotics. Risk-benefit considerations important in therapy, including patient’s co-morbidities medication used, as well compliance. If all these issues carefully considered, antimicrobials used at correct dose proper duration, infection can be successful....
Members of the Malassezia genus are lipophilic fungi that closely adapted to milieu skin areas rich in sebaceous glands. They most important fungal elements adult microbiome, with colonization starting immediately after birth. In recent years, their role pathogenesis many diseases has been suggested, however, data regarding actual function etiology each disease contradictory. our report, we would like present complex immunological mechanisms associated species, as well aspects related...
Leukaemia cutis is a relatively rare manifestation in chronic lymphocytic leukaemia, characterized by diverse morphology of skin lesions. We report two patients who developed zosteriform symptoms; however, the histological analysis revealed leukaemia infiltration as cause their symptoms. Contrary to previous reports, varicella zoster virus DNA was detectable These findings suggest that plays an active role development cutis.
A szerzők célja volt kideríteni, hogy azon gyógyszercsoportokban [aszkorbinsavat tartalmazó készítmények (AA), nem frakcionált heparin (UFH) és alacsony molekulatömegű (LMWH) készítmények, ízületi kopásra használt szerek, vas-és folsavpótló szerek], ahol a rutin limfocita transzformációs teszt (LTT) kimagaslóan sokszor pozitív, álpozitív reakció áll-e pozitív LTT eredmény hátterében. Egészséges kontroll személyeken random személye-
Psoriasis is a chronic inflammatory skin disorder; its genetic background has been widely studied in recent decades.Recognition of novel factors contributing to the pathogenesis this disorder was facilitated by potent molecular biology tools developed during 1990s.Large-scale gene expression studies, including differential display and microarray, have used experimental dermatology great extent; moreover, one first organs analyzed using these methods.We performed our comprehensive analysis...
Psychodermatology represents a frontier between dermatology and mental health-related sciences. It is well established that psychosocial stress may exacerbate the symptoms of dermatological disorders, alterations due to different skin conditions also affect health. A category psychological disorders characterized by prominent symptoms. Based on these facts, it evident psychotherapeutic intervention might be relevant in treatment lesions observation facilitate diagnosis an underlying...
A pikkelysömör (pszoriázis) a krónikus gyulladásos bőrbetegségek közül az egyik leggyakoribb, Európában lakosság legalább 2%-a érintett megbetegedésben.A betegség kialakulásának megértésében egészen új megközelítésnek számít emberi bőrt kolonizáló mikroorganizmusok (humán mikrobiom) vizsgálata.Kísérletes eredmények alapján pikkelysömörös bőrön megtelepedő mikrobatörzsek lényegében ugyanazok, mint egészséges bőrön, viszont vál-