A5101763744- Liver Disease Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Pharmacological Effects of Natural Compounds
- Pancreatic and Hepatic Oncology Research
- Cancer Research and Treatments
- Endometriosis Research and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Bone health and osteoporosis research
- Lower Extremity Biomechanics and Pathologies
- Colorectal Cancer Treatments and Studies
- Reproductive Biology and Fertility
- Assisted Reproductive Technology and Twin Pregnancy
- Cancer Mechanisms and Therapy
- Cancer Cells and Metastasis
- Liver physiology and pathology
- Diverticular Disease and Complications
- Ovarian function and disorders
- Reproductive Health and Technologies
- Endometrial and Cervical Cancer Treatments
- Caveolin-1 and cellular processes
- Radiomics and Machine Learning in Medical Imaging
- Esophageal Cancer Research and Treatment
- Traditional Chinese Medicine Analysis
- Computational Drug Discovery Methods
- Sesame and Sesamin Research
Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
2014-2025
First Affiliated Hospital of GuangXi Medical University
2023-2025
Guangxi Medical University
2023-2025
ShanghaiTech University
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2006-2024
Zhuhai Institute of Advanced Technology
2024
Guang’anmen Hospital
2018-2024
Beijing Hospital of Traditional Chinese Medicine
2021-2024
Beijing University of Chinese Medicine
2020-2023
Wenzhou Medical University
2014-2023
Abstract Treatment of intervertebral disc degeneration (IDD) seeks to prevent senescence and death nucleus pulposus (NP) cells. Previous studies have shown that sirt6 exerts potent anti-senescent anti-apoptotic effects in models age-related degenerative disease. However, it is not known whether protects against IDD. Here, we explored influenced The level was reduced senescent human NP Sirt6 overexpression protected apoptosis both replicative stress-induced premature senescence. also...
<title>Abstract</title> Gastric cancer is characterized by a high incidence and unfavorable prognosis. The exploration of novel molecular markers deeper understanding their mechanisms action hold the potential to offer fresh insights into gastric treatment. Leveraging TCGA-STAD GSE66254 datasets, this study conducted an analysis on relationship between GPR176 clinical pathological features. Furthermore, it was validated in patients from First Affiliated Hospital Guangxi Medical University....
BACKGROUND:Piperine has been reported to inhibit proliferation and induce apoptosis in various cancer cells. This study aimed explore the efficacy underlying mechanism of piperine human gastric cancer. MATERIAL AND METHODS:MTT assay was performed examine effect (concentrations 0–300 μM) on SNU-16 cells normal epithelial GES-1 Flow cytometry Western blot were used determine cell expression level protein (Cyto C, cleaved PARP, caspase-3, Bax, Bcl-2, Bad, Bcl-xl, PI3K, pPI3K, Akt, pAkt),...
The current therapies for endometriosis are restricted by various side effects and treatment outcome has been less than satisfactory. Shaofu Zhuyu Decoction (SZD), a classic traditional Chinese medicinal (TCM) prescription dysmenorrhea, widely used in clinical practice TCM doctors to relieve symptoms of endometriosis. present study aimed investigate the SZD on rat model Forty‐eight female Sprague‐Dawley rats with regular estrous cycles went through autotransplantation operation establish...
Salvia miltiorrhiza Bge. is a traditional Chinese medicine (TCM) that has been used for treatment of various diseases, including cancer by activating blood circulation and removing stasis. Tanshinone (TanIIA) cryptotanshinone (CPT) are major lipophilic compounds extracted from the root Bge., which considered to be effective affecting efficacy anti-tumor therapy We have explored mechanism CPT TanIIA exerting inhibition in non-small cell lung (NSCLC) provide experimental data support guiding...
Prostate cancer (PCa) is an age-related disease, and the stromal microenvironment plays important role in prostatic malignant progression.However, differences prostate cells present young old tissue are still obscure.We established primary cultured from normal peripheral zone (PZ) of donors varying ages found that (PZ-old) were more enlarged polygonal than those (PZ-young).Furthermore, based on immunocytochemical ultrastructural analysis, components changed a majority fibroblasts to mixture...
Breast cancer is the most common malignancy in women worldwide. Compared with other malignant tumors, breast patients have a higher incidence of depression and psychiatric symptoms. The purpose this meta-analysis was to determine association between long-term survival cancer.
This study aims to explore the characteristics and related factors of insomnia patients after operation for gastric cancer.A cross-sectional survey was carried out finally 115 with cancer were included. The general information, cancer-related sleep quality, other symptoms investigated.① Pittsburgh quality index score most surgery 11-15 points, rating "poor". ② is number chemotherapy cycles, fatigue, depression. ③ probability reduced cycles >6 3.640 times that ≤6. during moderate severe...
Abstract: Interleukin (IL)-12 has emerged to be a prospective molecule for antitumor therapies with many types of cancers. Here we examine the effect IL-12 treatment in preventing colorectal cancer liver metastasis mice model. At different doses, found that decreased formation sites and percentage volume liver. Additionally, this leads improved survival function after tumor cell transplantation. We believe based therapy provided novel patients suffering from metastasis. Keywords: IL-12,...