A5006651790- Neuroscience and Neuropharmacology Research
- Medicinal Plants and Neuroprotection
- Neuroinflammation and Neurodegeneration Mechanisms
- Cholinesterase and Neurodegenerative Diseases
- Phytochemistry and Biological Activities
- Pharmacological Effects of Natural Compounds
- Neurogenesis and neuroplasticity mechanisms
- GABA and Rice Research
- Natural product bioactivities and synthesis
- Neurotransmitter Receptor Influence on Behavior
- Olfactory and Sensory Function Studies
- Alzheimer's disease research and treatments
- Biochemical Analysis and Sensing Techniques
- Botanical Studies and Applications
- Ginseng Biological Effects and Applications
- Neurological Disease Mechanisms and Treatments
- Traditional Chinese Medicine Analysis
- Biochemical effects in animals
- Ziziphus Jujuba Studies and Applications
- Healthcare and Venom Research
- Chemical synthesis and alkaloids
- Nicotinic Acetylcholine Receptors Study
- Tryptophan and brain disorders
- Stress Responses and Cortisol
- Flavonoids in Medical Research
Daegu Haany University
2013-2023
Dong-A University
2022
Donga College of Health
2022
Convergence
2015
Kyung Hee University
2003-2007
Hallym University
2005
Seoul National University
2005
The purpose of this study was to characterize the putative anxiolytic-like effects aqueous extract rhizome Gastrodia elata along with its phenolic constituents, 4-hydroxybenzyl alcohol (HA) and 4-hyroxybenzaldehyde (HD), using an elevated plus maze (EPM) in mice. mice were administered either G. orally or received intraperitoneal injection 1 h before behavioral evaluation EPM. A single treatment significantly increased percentage time spent arm entries into open arms EPM versus saline...
Psychological stressors may cause affective disorders, such as depression and anxiety, by altering expressions of corticotropin releasing factor (CRF), serotonin (5-HT), tyrosine hydroxylase (TH) in the brain. This study investigated effects essential oil from Asarum heterotropoides (EOAH) on depression-like behaviors brain CRF, 5-HT, TH mice challenged with stress.Male ICR received fragrance inhalation EOAH (0.25, 0.5, 1.0, 2.0 g) for 3 h special cage capped a filter paper before start...
Memory impairment is the most common symptom in patients with Alzheimer's disease (AD). Angelica keiskei (AK) has traditionally been used as a diuretic, laxative, analeptic and galactagogue. However, anti-amnesic effects of AK its molecular mechanisms have yet to be clearly elucidated. The aim present study evaluate on scopolamine-induced memory impairments mice. regulatory effect was investigated using passive avoidance, Y-maze Morris water maze tasks. Acetylcholinesterase (AChE) activity...
The preventive effect of Anemarrhena asphodeloides BUNGE (Liliaceae), a traditional Chinese medicine, on ischemia-reperfusion-induced brain injury was evaluated in the rat brain. Ischemia induced by intraluminal occlusion right middle cerebral artery for 2 h and reperfusion continued 22 h. Water extract (WEAA) orally administered promptly prior to after reperfusion. Total infarct volume edema ipsilateral hemispheres ischemia-reperfusion rats were significantly reduced treatment with WEAA...
Alzheimer's disease, a neurodegenerative disorder, is characterized by progressive cognitive impairment associated with the disruption of cholinergic neurotransmission. The aim present study was to evaluate effect α- or β-amyrin, type pentacyclic triterpene, on induced scopolamine, muscarinic acetylcholine receptor antagonist. To measure abilities various types learning and memory, we conducted step-through passive avoidance task. Scopolamine deficits in memory processes mice, which were...
The traditional manufacturing method used to produce goods from Hizikia fusiforme, utilizes extraction steps with hot water. byproduct (of water extraction) is rich in polysaccharide and considered a waste. To evaluate the osteogenic effects of H. fusiforme (HFB), cells animal models were test it on osteogenesis. HFB-treated mouse myoblast C2C12 exhibited significant dose dependently elevated alkaline phosphatase (ALP) activity slightly increased bone morphogenetic protein-2 (BMP-2). HFB...
Alzheimer's disease (AD) is a progressive and most frequently diagnosed neurodegenerative disorder. However, there still no drug preventing the progress of this β-Amyrin, an ingredient surface wax tomato fruit dandelion coffee, previously reported to ameliorate memory impairment induced by cholinergic dysfunction. Therefore, we tested whether β-amyrin can prevent AD-like pathology. β-Amyrin blocked amyloid β (Aβ)-induced long-term potentiation (LTP) in hippocampal slices. Moreover, improved...