A5029228626- Cardiovascular Effects of Exercise
- Cardiac Arrest and Resuscitation
- Cardiac electrophysiology and arrhythmias
- Autopsy Techniques and Outcomes
- Cardiac Structural Anomalies and Repair
- Coronary Artery Anomalies
- Kawasaki Disease and Coronary Complications
- Viral Infections and Immunology Research
- Cardiovascular Issues in Pregnancy
- Cardiovascular Function and Risk Factors
- Sports injuries and prevention
- Trauma and Emergency Care Studies
- Cardiac pacing and defibrillation studies
- Cardiac Health and Mental Health
- Forensic Toxicology and Drug Analysis
- Cardiomyopathy and Myosin Studies
- Gastrointestinal disorders and treatments
- Schizophrenia research and treatment
- Cardiac Imaging and Diagnostics
- Opioid Use Disorder Treatment
- Pancreatitis Pathology and Treatment
- Cardiac Valve Diseases and Treatments
- Forensic Entomology and Diptera Studies
- Trauma Management and Diagnosis
- Restraint-Related Deaths
Victorian Institute of Forensic Medicine
2016-2025
Monash University
2016-2025
The Royal Melbourne Hospital
2022
The University of Melbourne
2022
Parsons (United States)
2020
La Trobe University
2013
Austin Hospital
2006
Austin Health
2005
Royal Children's Hospital
2003
Australia New Zealand Gynaecological Oncology Group
1998
Sudden cardiac death is, by definition, an unexpected, untimely caused a condition in person with known or unknown heart disease. This major international public health problem accounts for approximately 15-20% of all deaths. Typically more common older adults acquired disease, SCD also can occur the young where cause is likely to be genetically transmitted process. As these inherited disease processes affect multiple family members, it critical that deaths are appropriately and thoroughly...
The causes, circumstances, and preventability of young sudden cardiac arrest remain uncertain.A prospective state-wide multi-source registry identified all out-of-hospital arrests (OHCAs) in 1-50 year olds Victoria, Australia, from 2019 to 2021. Cases were adjudicated using hospital forensic records, clinic assessments interviews survivors family members. For confirmed causes OHCA, circumstances history collected. National time-use data was used contextualize circumstances. 1319 OHCAs...
Spontaneous coronary artery dissection (SCAD) is a cause of acute syndromes and in rare cases sudden cardiac death (SCD). Connective tissue abnormalities, inflammation, increased vasa vasorum (VV) density, fibromuscular dysplasia have all been implicated the pathophysiology SCAD but not previously systematically assessed. We designed study to investigate histological dermal collagen ultrastructural findings SCAD.Thirty-six autopsy were compared with 359 survivors. Coronary myocardial...
Background The association between mitral valve prolapse (MVP) and sudden death remains controversial. We aimed to describe histopathological changes in individuals with autopsy-determined isolated MVP (iMVP) document cardiac arrest rhythm. Methods Results Australian National Coronial Information System database was used identify cases of iMVP 2000 2018. Histopathological were compared 2 control cohorts matched for age, sex, height, weight (1 group noncardiac 1 death). Data linkage ambulance...
Unexplained sudden cardiac death (SCD) may be attributable to cardiogenetic disease. Presence or absence of autopsy anomalies detected following premature direct appropriate clinical evaluation at-risk relatives towards inherited cardiomyopathies primary arrhythmia syndromes, respectively. We investigated the relevance non-diagnostic pathological abnormalities indeterminate causality (uncertain) such as myocardial hypertrophy, fibrosis, inflammatory infiltrates SCD.At-risk unexplained SCD...
Abstract Postmortem imaging (PMI) is increasingly used in postmortem practice and considered a potential alternative to conventional autopsy, particularly case of sudden cardiac deaths (SCD). In 2017, the Association for European Cardiovascular Pathology (AECVP) published guidelines on how perform an autopsy such cases, which still gold standard, but diagnostic value PMI herein was not analyzed detail. At present, significant progress has been made diagnosis acute ischemic heart disease,...
Little information is available regarding the extent of strategy use and factors that affect in amnestic mild cognitive impairment (aMCI). This study aimed to compare spontaneous beliefs about controllability memory between aMCI healthy older adult (HOA) samples explore relationships beliefs, use, performance for both groups. The HOA groups each composed 60 individuals matched age education. Memory Controllability Inventory was used assess control semantic clustering on a list-learning task...
Abstract The accumulation of myofibroblasts within the intimal layer inflamed blood vessels is a potentially catastrophic complication vasculitis, which can lead to arterial stenosis and ischaemia. In this study, we have investigated how these luminal develop during Kawasaki disease (KD), paediatric vasculitis typically involving coronary arteries. By performing lineage tracing studies in murine model KD, reveal that independently adventitial fibroblasts endothelial cells, instead derive...
To contextualize obesity rates in young sudden cardiac death (SCD) against the age-matched national population, and identify clinical pathologic features WHO class II III obesity.A prospective state-wide out-of-hospital arrest registry included all SCDs Victoria, Australia from 2019-2021. Body mass indices (BMIs) of patients 18-50 years were compared to age-referenced general population. Characteristics SCD with Class (BMI ≥30kg/m2) non-obesity (BMI<30kg/m2) compared. Clinical...
Summary: The case records of 11 patients with cystic fibrosis (CF) who had 13 completed pregnancies between 1975 and 1995 were retrospectively reviewed to assess: (1) the changes in spirometry body mass index (BMI) during pregnancy; (2) maternal neonatal complications outcomes. Prepregnancy mean age group was 24 (range 17–27) years. Two exsmokers, 7 pancreatic insufficiency chest X‐ray evidence bronchiectasis. None diabetes mellitus but 3 developed gestational diabetes. ± SEM (% predicted)...