A5070899519- Childhood Cancer Survivors' Quality of Life
- Synthesis and biological activity
- Muscle Physiology and Disorders
- Synthesis and Characterization of Heterocyclic Compounds
- Cerebral Palsy and Movement Disorders
- Synthesis and Reactions of Organic Compounds
- Synthesis and Reactivity of Sulfur-Containing Compounds
- Children's Physical and Motor Development
- Synthesis of heterocyclic compounds
- Structural and Chemical Analysis of Organic and Inorganic Compounds
- Acute Lymphoblastic Leukemia research
- Vestibular and auditory disorders
- Neuroscience and Neural Engineering
- Synthesis of Organic Compounds
- Cardiac, Anesthesia and Surgical Outcomes
- Cancer survivorship and care
- Neurogenetic and Muscular Disorders Research
- Adolescent and Pediatric Healthcare
- Aortic aneurysm repair treatments
- Hematopoietic Stem Cell Transplantation
- Chronic Myeloid Leukemia Treatments
- Asymmetric Synthesis and Catalysis
- Phenothiazines and Benzothiazines Synthesis and Activities
- Synthesis and Biological Activity
- Transcranial Magnetic Stimulation Studies
University of Turin
2009-2024
Ospedale Regina Margherita
2014-2024
University of Modena and Reggio Emilia
2022-2023
Azienda Unita' Sanitaria Locale Di Modena
2022
Azienda Ospedaliera Citta' della Salute e della Scienza di Torino
2022
International Agency for the Prevention of Blindness
2020
Fondazione IRCCS Istituto Neurologico Carlo Besta
2014
KU Leuven
2014
Meyer Children's Hospital
2013
University of Genoa
1992-2011
A large series of substituted chalcones have been synthesized and tested in vitro for their ability to inhibit human monoamine oxidases B (hMAO-A hMAO-B). While all the compounds showed hMAO-B selective activity micro- nanomolar ranges, best results were obtained presence chlorine hydroxyl or methoxyl substituents. To better understand enzyme-inhibitor interaction explain selectivity most active toward hMAO-B, molecular modeling studies carried out on new, high resolution, crystallographic...
The aim of the study was to assess different outcome measures in a cohort ambulant boys with Duchenne muscular dystrophy (DMD) over 12 months order establish spectrum possible changes relation age and steroid treatment.The is longitudinal multicentric study. A total 106 patients DMD were assessed using 6-minute walk test (6MWT) North Star Ambulatory Assessment (NSAA) at baseline months. Clinical data including treatment collected.During study, we observed mean decline 25.8 meters 6MWT SD...
The 6 minute walk test has been recently chosen as the primary outcome measure in international multicenter clinical trials Duchenne muscular dystrophy ambulant patients. aim of study was to assess spectrum changes at 3 years individual measures, their correlation with steroid treatment, age and values baseline. Ninety-six patients from 11 centers were assessed baseline 12, 24 36 months after using North Star Ambulatory Assessment. Three boys (3%) lost ability perform within 12 months,...
Objectives The aim of the study was i) to assess spectrum changes over 24 months in ambulant boys affected by Duchenne muscular dystrophy, ii) establish difference between first and second year results iii) identify possible early markers loss ambulation. Methods One hundred thirteen patients (age range 4.1–17, mean 8.2) fulfilled inclusion criteria, 67 113 were on daily 40 intermittent steroids, while 6 not steroids. All assessed using Minute Walk Test (6MWT), North Star Ambulatory...
Objective In the last few years some of therapeutical approaches for Duchenne muscular dystrophy (DMD) are specifically targeting distinct groups mutations, such as deletions eligible skipping individual exons. The aim this observational study was to establish whether patients with mutations have different profiles changes on 6 minute walk test (6MWT) over a 12 month period. Methods 6MWT performed in 191 ambulant DMD boys at baseline and months later. results were analysed using...
Abstract Physical activity (PA) and exercise are safe beneficial for children adolescents affected by cancer. Yet, this population is not active enough to receive benefits. PA guideline recommendation statements can support individual behavior practice change. The purpose of project was develop the international Pediatric Oncology Exercise Guidelines (iPOEG), comprised statements, promote among Guideline development procedures, stakeholder engagement strategies, Delphi technique were used....
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAzoalkenes as Intermediate Compounds in the Formation of Osazones from α-Acetoxy KetonesL. Caglioti, G. Rosini, and F. RossiCite this: J. Am. Chem. Soc. 1966, 88, 16, 3865–3866Publication Date (Print):August 1, 1966Publication History Published online1 May 2002Published inissue 1 August 1966https://pubs.acs.org/doi/10.1021/ja00968a038https://doi.org/10.1021/ja00968a038research-articleACS PublicationsRequest reuse permissionsArticle...
Abstract Background In response to the imperative need for standardized support adolescent Gender Dysphoria (GD), Italian Academy of Pediatrics, in collaboration with Society Pediatric Endocrinology and Diabetes, Adolescent Medicine Child Neuropsychiatry is drafting a position paper. The purpose this paper convey author's opinion on topic, offering foundational information potential aspects gender-affirming care emphasizing protection children adolescents GD. Main body Recognizing that may...
The management of children with cancer during the end-of-life (EOL) period is often difficult and requires skilled medical professionals. Patients tumors central nervous system (CNS) relapse or disease progression might have additional needs because presence unique issues, such as neurological impairment altered consciousness. Very few reports specifically concerning EOL in pediatric neuro-oncology are available.Among all patients followed at our center EOL, we retrospectively analyzed data...
Occipital strokes often cause permanent homonymous hemianopia leading to significant disability. In previous studies, non-invasive electrical brain stimulation (NIBS) has improved vision after optic nerve damage and in combination with training stroke.We explored different NIBS modalities for rehabilitation of chronic stroke.In a randomized, double-blinded, sham-controlled, three-armed trial, altogether 56 patients were recruited. The three experiments were: i) repetitive transorbital...
In Italy, 1400 children and 800 adolescents are diagnosed with cancer every year. About 80% of them can be cured but at high risk experiencing severe side effects, many which respond to rehabilitation treatment. Due the paucity literature on this topic, Italian Association Pediatric Hematology Oncology organized a Consensus Conference role motor impairments in children/adolescents affected by leukemia, central nervous system tumors, bone state recommendations improve clinical practice. This...