- Phytochemicals and Antioxidant Activities
- Horticultural and Viticultural Research
- Fermentation and Sensory Analysis
- Plant Pathogens and Fungal Diseases
- Tea Polyphenols and Effects
- Sirtuins and Resveratrol in Medicine
- Plant biochemistry and biosynthesis
- Plant Disease Management Techniques
- Natural product bioactivities and synthesis
- Plant tissue culture and regeneration
- Plant Virus Research Studies
- Insect and Pesticide Research
- Chromatography in Natural Products
- Biochemical and biochemical processes
- Plant-Microbe Interactions and Immunity
- Biochemical Analysis and Sensing Techniques
- Insect-Plant Interactions and Control
- Phytochemistry and Biological Activities
- Metabolomics and Mass Spectrometry Studies
- Antioxidant Activity and Oxidative Stress
- Nuts composition and effects
- Plant Parasitism and Resistance
- Mycorrhizal Fungi and Plant Interactions
- Research in Cotton Cultivation
- Biochemical effects in animals
Unité de Recherche Œnologie
2007-2025
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2020-2025
Université de Bordeaux
2008-2025
Institut Polytechnique de Bordeaux
2021-2025
MetaboHUB
2020-2025
Oenology Research Unit
2017-2024
École Nationale Supérieure des Sciences Agronomiques de Bordeaux-Aquitaine
2022-2024
Biologie du Fruit et Pathologie
2024
Molécules d'Intérêt Biologique
2019-2023
Centre National de la Recherche Scientifique
2020
Procyanindin extract (PE) is a mixture of polyphenols, mainly procyanidins, obtained from grape seed with putative antiinflammatory activity. We evaluated the PE effect on RAW 264.7 macrophages stimulated lipopolysaccharide plus interferon-γ that show rapid enhanced production prostaglandin E2 (PGE2) and nitric oxide (NO). Our results demonstrated significantly inhibited overproduction NO, dose time dependently. caused marked inhibition PGE2 synthesis when administered during activation....
Among procyanidins (PC), monomers, such as catechin and epicatechin, have been widely studied, whereas dimer trimer oligomers received much less attention, despite their abundance in our diet. Recent studies showed that dimers trimers could be important determining the biological effects of procyanidin-rich food, understanding bioavailability metabolism is fundamental. The purpose present work to study stability PC under digestion conditions, by using a combination vitro vivo models....
The aim of this paper is to study how grape ripeness and ethanol concentration affect the extraction color phenolic compounds from skins seeds during maceration/fermentation process. Simulated maceration assays were carried out with grapes at three stages berry development (vitis vinifera cv. Tempranillo) different percentages in media. Both content have a considerable effect on compounds. Of these two factors, increases extractability most. presence medium facilitates anthocyanin especially...
Phenolics from grapes and wines can play a role against oxidation development of atherosclerosis. Stilbenes have been shown to protect lipoproteins oxidative damage cancer chemopreventive activity. We describe method for the direct determination stilbenes in several red using high-performance liquid chromatography with UV detection. In survey 12 commercial south Brazil (Rio Grande del Sul), levels delta-viniferin are reported first time different varieties wines. Brazilian wine contains...
In recent years, biofungicides have drawn increasing interest in vineyards for a more sustainable integrated and copper-limited pest management. Among alternatives, botanicals could represent valuable tools, being rich sources of biologically active compounds. Conversely to the well-known antioxidant biological properties relation health benefits, investigation on bioactivity hot pungent Capsicum sp. products against fungal phytopathogens is still scarce. Therefore, present study aimed at...
In the analysis of biological samples, such as plasma or serum, quantity sample available is a critical parameter in most cases. A good approach use microelution SPE (μSPE) plates pre-treatment technique which loaded volume low. An off-line μSPE and ultra-performance LC-ESI-MS/MS (UPLC-ESI-MS/MS) method was developed validated to determine procyanidins anthocyanins spiked samples. The allowed simultaneous determination from by using small (350 μL) without an evaporation step previous...
Plants deposit photosynthetically-fixed carbon in the rhizosphere, thin soil layer directly around root, thereby creating a hospitable environment for microbes. To manage inhabitants of this nutrient-rich environment, plant roots exude and dynamically adjust microbe-attracting -repelling compounds to stimulate specific members microbiome. Previously, we demonstrated that foliar infection Arabidopsis thaliana by biotrophic downy mildew pathogen Hyaloperonospora arabidopsidis (Hpa) leads...
Excisional wounds are considered one of the most common physical injuries. This study aims to test effect a nanophytosomal formulation loaded with dried hydroalcoholic extract S. platensis on promoting excisional wound healing. The Spirulina (SPNP) containing 100 mg PC and 50 CH exhibited optimum physicochemical characteristics regarding particle size (598.40 ± 9.68 nm), zeta potential (-19.8 0.49 mV), entrapment efficiency (62.76 1.75%), Q6h (74.00 1.90%). It was selected prepare an HPMC...
Grapevine canes are an abundant byproduct of the wine industry. The stilbene contents Vitis vinifera cultivars have been largely studied, but little is known about wild accessions. Moreover, there only few studies on quantification other phenolic compounds in just pruned grapevine canes. In our study, we investigated polyphenol profile 51 genotypes belonging to 15 spp. A total 36 polyphenols (20 stilbenes, 6 flavanols, 7 flavonols, and 3 acids) were analyzed by high-performance liquid...
Three recognized plant defense stimulators (PDS), methyl jasmonate (MeJA), benzothiadiazole (BTH) and phosphonates (PHOS), were sprayed on grapevine Vitis vinifera cuttings conferred resistance to the biotrophic pathogen Plasmopara viticola. The effects molecular defense-related genes polyphenol content (stilbenes flavanols) revealed at 6 8 days post-elicitation. transcript accumulation was consistent with signaling pathway specific elicitor, salicylic acid for BTH, jasmonic MeJA, some...
Applying organic amendments to vineyard soil improves properties and vine development by increasing water retention nutrient content. However, little is known about how mulches modify grapevine phenolic composition. This study analysed the profile in leaves, canes, grape skins of Tempranillo over 3 years two locations with three mulches: spent mushroom compost (SMC), pruning debris (GPD) straw (STR), as well conventional practices: herbicide (HERB) tillage (TILL). Seventy compounds were...
Mycorrhizal fungal species are widespread across nearly all ecosystems worldwide and generally found in symbiotic association with most plant species. In forested ecosystems, mycorrhizal fungi play a crucial role facilitating nutrient acquisition defending the from abiotic biotic stress events, such as drought or pathogen attack.We have recently shown that different tree associate either arbuscular (AM) ectomycorrhizal (EM) exhibit distinct phytochemical differences, might be linked to type...
Light reflectance by foliage across visible and infrared wavebands is determined chemical structural traits that reveal how plants evolved to support growth defense in different climate environments. These spectral fingerprints have emerged as powerful tools estimate plant functional taxonomic diversity scales, giving rise a new approach ecology called spectranomics. In this context, the widespread co-evolution of with mycorrhizal fungi has likely led chemical, thus dissimilarities are...
Downy mildew (Plasmopara viticola) is one of the most devastating diseases for European grapevines (Vitis vinifera L.), requiring extensive use copper-based or synthetic pesticides. Due to negative effects these products (e.g., impacts on environment and human health, acquisition pathogen resistance), there a crucial need develop alternative strategies controlling downy in vineyard. Tannins are compounds that directly toxic diverse microorganisms, but little known about their antimicrobial...
Background: TOTUM-854 is a patented plant extract blend characterized by its components that have previously been described for their potential health benefits in limiting hypertension onset. However, most of the literature data remain descriptive regarding mode action at cellular level, especially humans, and further investigations are required optimized therapeutic strategies. Methods: We first demonstrated an L-NAME mouse model supports prevention vitro vivo. Then, we designed ex vivo...
Protecting vineyards from cryptogamic diseases such as downy mildew, caused by Plasmopara viticola, generally requires a massive use of phytochemicals. However, the issues on unintentional secondary effects environment and human health, occurrence P. viticola resistant strains, are leading to development alternative strategies, biocontrol products. In this paper, we evidenced ability plant extract protect grapevine viticola. Further experiments carried out both cell suspensions plants...
Abstract Introduction Grapevine wood and roots are by‐products obtained during vineyard management. This plentiful biomass is known to be rich in stilbenes can used as a source of high‐value compounds well active natural extracts. However, the grapevine from different cultivars rootstocks remain characterized. Objective The present study investigated stilbene content eight major Vitis vinifera six rootstocks. In addition, distribution was established for each seven parts into which plants...
Abstract Background Grafting with rootstocks is essential for the culture of many perennial fruit crops and increasing being used in production annual fruits vegetables. Our previous work based on microarrays showed that transcripts encoding enzymes both primary secondary metabolism were differentially expressed during graft union formation homo-grafts (a genotype grafted itself) hetero-grafts (two different genotypes together). The aim this study was to profile metabolites, quantify...
Abstract Grafting is an important horticultural technique used for many crop species. However, some scion/rootstock combinations are considered as incompatible due to poor graft union formation and subsequently high plant mortality. The early identification of incompatibility could allow the selection non-viable plants before planting would have a beneficial impact on research development in nursery sector. In general, visible phenotypes grafted (size, root number, etc.) poorly correlated...