A5053429229- Nuclear Materials and Properties
- Nuclear reactor physics and engineering
- Neuropeptides and Animal Physiology
- Molten salt chemistry and electrochemical processes
- Pain Mechanisms and Treatments
- Pharmacological Receptor Mechanisms and Effects
- Receptor Mechanisms and Signaling
- Pharmacological Effects of Natural Compounds
- Radioactive element chemistry and processing
- Fusion materials and technologies
- Thermodynamic and Structural Properties of Metals and Alloys
- Stress Responses and Cortisol
- Glycosylation and Glycoproteins Research
- Neuroscience and Neuropharmacology Research
- Advanced MIMO Systems Optimization
- Wireless Communication Networks Research
- Extraction and Separation Processes
- Metallurgical Processes and Thermodynamics
- Nuclear materials and radiation effects
- Neuroinflammation and Neurodegeneration Mechanisms
- Ion channel regulation and function
- Hereditary Neurological Disorders
- Nuclear and radioactivity studies
- Advanced Wireless Communication Techniques
- Advanced Wireless Network Optimization
Kitasato University
2015-2024
Pharmac
2019-2023
Tokyo University of Science
1974-2022
Saiseikai Shimonoseki General Hospital
2016-2018
Osaka University
2017
National Institute of Mental Health
2011-2014
National Center of Neurology and Psychiatry
2010-2014
Japan Atomic Energy Agency
2001-2014
Panasonic (Japan)
2009-2013
Advanced Science Research Center
2005
Abstract Aim We previously reported that oxytocin, a peptide hormone, can reverse the β‐amyloid (25–35) (Aβ 25–35 )‐induced impairments of murine hippocampal synaptic plasticity. In this study, we examined effects oxytocin on Aβ ‐induced impairment cognitive behavior in order to investigate potential as clinical treatment tool for Alzheimer's disease (AD). Methods The Y‐maze and Morris water maze (MWM) tests were performed. Since intracerebroventricular (ICV) administration is both invasive...
Sonazoid is a new contrast agent for ultrasonography (US). Contrast-enhanced (CEUS) using enables Kupffer imaging, which improves the sensitivity of hepatocellular carcinoma (HCC) detection. However, there are no studies on cost-effectiveness HCC surveillance Sonazoid. We constructed Markov model simulating natural history HCV-related liver cirrhosis (LC) patients, and compared three strategies (no surveillance, US CEUS surveillance). The transition probability cost data were obtained from...
Glucagon‐like peptide‐1 (GLP‐1) is derived from the processing of proglucagon in intestinal L‐cells and releases insulin pancreatic β‐cells as an incretin. The GLP‐1 receptor has been proposed a possible therapeutic target for treatment Alzheimer's disease, which neuroinflammation critical pathogenesis. present study investigates whether (7–36) amide, active fragment GLP‐1, protected against synaptic impairments induced by inflammation‐related injurious agents (lipopolysaccharide [LPS],...