A5021188315- Urological Disorders and Treatments
- Renal cell carcinoma treatment
- Neural dynamics and brain function
- Bladder and Urothelial Cancer Treatments
- Urologic and reproductive health conditions
- Diabetes Treatment and Management
- Neuroscience and Neural Engineering
- Cancer, Hypoxia, and Metabolism
- Urinary and Genital Oncology Studies
- Diet and metabolism studies
- Kidney Stones and Urolithiasis Treatments
- Ureteral procedures and complications
- Pancreatic function and diabetes
- Hormonal Regulation and Hypertension
- Metabolism, Diabetes, and Cancer
- EEG and Brain-Computer Interfaces
- Prostate Cancer Diagnosis and Treatment
- Evolutionary Algorithms and Applications
- Renal and related cancers
- Urinary Bladder and Prostate Research
- Genital Health and Disease
- Liver Disease Diagnosis and Treatment
- Cardiovascular Health and Disease Prevention
- Epigenetics and DNA Methylation
- Medical Imaging and Pathology Studies
Sainsbury Laboratory
2016-2025
University College London
2016-2025
Aristotle University of Thessaloniki
2013-2024
Emory University
2024
MathWorks (United States)
2024
Champalimaud Foundation
2016-2023
University of Chicago
2023
National and Kapodistrian University of Athens
2014-2022
University General Hospital Attikon
2011-2022
Patients First
2022
In white blood cells (WBC), the increase in glucose utilization is a prominent feature during immune response and this depends on function of specific transporter (GLUT) isoforms. The objective was to examine effects activation by Phorbol 12-myristate 13-acetate (PMA) or lipopolysaccharide (LPS) insulin expression GLUT isoforms all subpopulations WBC.Blood withdrawn from 27 healthy subjects. GLUT1, GLUT3 GLUT4 plasma membrane resting activated monocytes, T- B-lymphocytes polymorphonuclear...
Congenital coronary anomalies are uncommon with an incidence ranging from 0.17 % in autopsy cases to 1.2 angiographically evaluated cases. The recent development of ECG-gated multi-detector row computed tomography (MDCT) angiography allows accurate and noninvasive depiction artery anomalies.This retrospective study included 2572 patients who underwent 64-slice MDCT January 2008 March 2012. Coronary angiographic scans were obtained injection 80 ml nonionic contrast medium. Retrospective...
Electrophysiology is entering the era of big data. Multiple probes, each with hundreds to thousands individual electrodes, are now capable simultaneously recording from many brain regions. The major challenge confronting these new technologies transforming raw data into physiologically meaningful signals, that is, single unit spikes. Sorting spike events neurons a spatiotemporally dense sampling extracellular electric field problem has attracted much attention (Rey, Pedreira, & Quian...
The role of motor cortex in non-primate mammals remains unclear. More than a century stimulation, anatomical and electrophysiological studies has implicated neural activity this region with all kinds movement. However, following the removal cortex, rats retain most their adaptive behaviors, including previously learned skilled movements. Here we revisit these two conflicting views present new behavior assay, challenging animals to respond unexpected situations while navigating dynamic...
To realise a research project idea, an experimenter faces series of conflicting design and implementation considerations, regarding both its hardware software components. For instance, the ease implementation, in time expertise, should be balanced against future reconfigurability number ‘black box’ Other, often conflicting, considerations include level documentation reproducibility, resource availability as well access to online communities. alleviate this balancing act between opposing...
The aim of this pilot study is to evaluate sarcosine, uracil, and kynurenic acid in urine as potential biomarkers prostate cancer detection progression monitoring. Sarcosine, were measured samples 32 patients prior radical prostatectomy, 101 with increased prostate-specific antigen ultrasonographically-guided prostatic biopsy collected before after massage, 15 healthy volunteers (controls). results related histopathologic data, Gleason score, PSA (Prostate Specific Antigen). Metabolites...
The small size (58 residues) and simple structure of the B domain staphylococcal protein A (BdpA) have led to this being a paradigm for theoretical studies folding. Experimental folding BdpA been limited by rapidity its kinetics. We report kinetics fluorescent mutant (G29A F13W), named F13W * , using nanosecond laser-induced temperature jump experiments. Automation apparatus has permitted large data sets be acquired that provide excellent signal-to-noise ratio over wide range experimental...
To study the analgesic effect of electroacupuncture (EA) as perioperative adjunctive therapy added to a systemic strategy (including tramadol and ketamine) for postoperative pain, opioid-related side effects patient satisfaction.In sham-controlled participant- observer-blinded trial, 75 patients undergoing radical prostatectomy were randomly assigned two groups: (1) EA (n=37; tramadol+ketamine+EA) (2) control (n=38; tramadol+ketamine). (100 Hz frequency) was applied at LI4 bilaterally during...
Limited data exist concerning the presence of polycystic ovary syndrome (PCOS) in premenopausal women with nonalcoholic fatty liver disease (NAFLD). We aimed to investigate prevalence PCOS overweight and obese NAFLD.Prospective, observational, cross-sectional study.We studied 110 apparently healthy, overweight, (BMI: 25.1-49.1 kg/m(2)) (age: 18-45 years) reporting no or minimal alcohol consumption for NAFLD abdominal ultrasonography after excluding causes secondary (Rotterdam criteria)...
Common autoimmune diseases tend to coexist in the same patients. Few studies have examined possible association between thyroiditis and psoriasis or psoriatic arthritis (PsA), with inconsistent results.To investigate prevalence of patients without PsA, living an iodine-sufficient area.We studied prospectively, 114 disease duration 5-38 years, 30 them 286 age- body mass index (BMI)-matched subjects known thyroid disease. A detailed medical history was obtained from all participants clinical...
Abstract We built a rig to perform patch-clamp and extracellular recordings from the same neuron in vivo. In this setup, axes of two micromanipulators are precisely aligned their relative position tracked real-time, allowing us accurately target neurons near an probe. used setup generate publicly-available dataset where cortical neuron’s spiking activity is recorded next dense CMOS Neuropixels “Ground-truth” datasets kind rare but valuable neuroscience community, as they power development...
We demonstrate distinct α- (7-14 Hz) and β-band (15-30 rhythms in rat somatosensory cortex vivo using epidural electrocorticography recordings. Moreover, we show rats that a genuine β-rhythm coexists alongside β-activity reflects the second harmonic of arch-shaped α-rhythm. This demonstration depends on novel quantification neuronal oscillations is based their rhythmic nature: lagged coherence. Using coherence, provide two lines evidence this from The first rhythms' spatial properties:...
Abstract It is an uninformative truism to state that the brain operates at multiple spatial and temporal scales, each with own set of emergent phenomena. More worthy attention point our current understanding it cannot clearly indicate which these phenomenological scales are significant contributors brain’s function primary output (i.e. behaviour). Apart from sheer complexity problem, a major contributing factor this affairs lack instrumentation can simultaneously address without causing...
Rectal bleeding is frequently seen in patients undergoing transrectal ultrasound (TRUS)-guided multiple biopsy of the prostate, but usually mild and stops spontaneously. We report what believed to be first case life-threatening rectal following this procedure, which was successfully treated by endoscopic intervention through placement three clips on sites bleeding. This emphasizes associated with endoclipping as a safe effective method achieve hemostasis massive after prostate biopsy....
Abstract The role of motor cortex in non-primate mammals remains unclear. More than a century stimulation, anatomical and electrophysiological studies has implicated neural activity this region with all kinds movement. However, following the removal cortex, rats retain most their adaptive behaviours, including previously learned skilled movements. Here we revisit these two conflicting views present new behaviour assay, challenging animals to respond unexpected situations while navigating...
Background: In hyperthyroidism, tissue glucose disposal is increased to adapt high energy demand. Our aim was examine the transporter isoforms involved in this process and their regulation through insulin monocytes from subjects with hyperthyroidism. Methods: Blood (20 ml) withdrawn 12 healthy hyperthyroid subjects. The abundance of (GLUT) on monocyte surface membrane determined absence presence (10 - 100 mU/l) using flow cytometry. Anti-CD14-PE monoclonal antibody used for gating. GLUT were...
Urinothorax (UT) is a rare and often undiagnosed condition, defined as the presence of urine in pleural cavity due to retroperitoneal leakage accumulation, known urinoma, into space. UT usually transudative effusion that presents patients with obstructive uropathy it may occur following surgical procedures ureter or kidney such ESWL, PCNL, URS. Its diagnosis requires high degree clinical suspicion since respiratory symptoms tend be absent mild urological signs dominate. However, rarely...