A5086581232- Economic and Financial Impacts of Cancer
- Cancer survivorship and care
- Health Systems, Economic Evaluations, Quality of Life
- Breast Cancer Treatment Studies
- Cancer Treatment and Pharmacology
- Global Cancer Incidence and Screening
- Multiple and Secondary Primary Cancers
- Cancer Immunotherapy and Biomarkers
- Estrogen and related hormone effects
- Cancer, Stress, Anesthesia, and Immune Response
- Chemotherapy-related skin toxicity
- Palliative Care and End-of-Life Issues
- Advanced Breast Cancer Therapies
- Childhood Cancer Survivors' Quality of Life
- HER2/EGFR in Cancer Research
- Immunotherapy and Immune Responses
- COVID-19 and healthcare impacts
- Neutropenia and Cancer Infections
- Nonmelanoma Skin Cancer Studies
- Cancer-related cognitive impairment studies
- Lymphatic System and Diseases
- Cancer Cells and Metastasis
- Medication Adherence and Compliance
- Prostate Cancer Treatment and Research
- Cancer Risks and Factors
Memorial Sloan Kettering Cancer Center
2016-2025
Kettering University
2011-2025
Cornell University
2003-2023
City of Hope
2022
Counseling Center
2021
Faculty of 1000 (United States)
2020
University of Ottawa
2018
University of Toronto
2018
McMaster University
2018
Wayne State University
2018
BACKGROUND Cancer and its treatment lead to increased financial distress for patients. To the authors' knowledge, date, no standardized patient‐reported outcome measure has been validated assess this distress. METHODS Patients with AJCC Stage IV solid tumors receiving chemotherapy at least 2 months were recruited. Financial toxicity was measured by COmprehensive Score Toxicity (COST) measure. The authors collected data regarding patient characteristics, clinical trial participation, health...
Electronic systems that facilitate patient-reported outcome (PRO) surveys for patients with cancer may detect symptoms early and prompt clinicians to intervene.To evaluate whether electronic symptom monitoring during treatment confers benefits on quality-of-life outcomes.Report of secondary outcomes from the PRO-TECT (Alliance AFT-39) cluster randomized trial in 52 US community oncology practices PRO or usual care. Between October 2017 March 2020, 1191 adults being treated metastatic were...
ASCO is committed to addressing the needs of sexual and gender minority (SGM) populations as a diverse group at risk for receiving disparate care having suboptimal experiences, including discrimination, throughout cancer continuum. This position statement outlines five areas recommendations address both SGM affected by members oncology workforce who identify SGM: (1) patient education support; (2) development diversity; (3) quality improvement strategies; (4) policy solutions; (5) research...
The Standardized Definitions for Efficacy End Points (STEEP) criteria, established in 2007, provide standardized definitions of adjuvant breast cancer clinical trial end points. Given the evolution trials and improvements outcomes, a panel experts reviewed STEEP criteria to determine whether modifications are needed.We conducted systematic searches ClinicalTrials.gov systemic local-regional therapy investigate if primary points reported met criteria. On basis common deviations, we performed...
Breast cancer affects one in eight women across the United States, and low-income minority survivors of breast are at increased risk job loss, compared to higher-income white survivors. Employer accommodations, such as schedule flexibility, have been associated with retention whites, but role accommodations among minorities is not well understood. We conducted a longitudinal study 267 employed ages 18-64 who were undergoing treatment for early-stage spoke English, Chinese, Korean, or...
Abstract Aims The most appropriate timing of exercise therapy to improve cardiorespiratory fitness (CRF) among patients initiating chemotherapy is not known. effects administered during, following, or during and following were examined in with breast cancer. Methods results Using a parallel-group randomized trial design, 158 inactive women cancer (neo)adjuvant allocated receive (1:1 ratio): usual care one three regimens—concurrent (during only), sequential (after concurrent (continuous) (n =...
Financial toxicity (FT) affects 20% of cancer survivors and is associated with poor clinical outcomes. No large-scale programs have been implemented to mitigate FT. We evaluated the effect monthly FT screening as part a larger patient-reported outcomes (PROs) digital monitoring intervention.
Abstract BACKGROUND: Previous research has found an 80% return‐to‐work rate in mid‐income white breast cancer survivors, but little is known about the employment trajectory of low‐income minorities or whites. We set out to compare trajectories Latina and non‐Latina survivors identify correlates status. METHODS: Participants were women who had localized cancer, spoke English Spanish, employed at time diagnosis. Interviews conducted 6, 18, 36 months after Multivariate logistic regression was...
Food insecurity is prevalent among low-income immigrant and minority patients with cancer. To our knowledge, this randomized controlled trial the first to prospectively examine impact on cancer outcomes of food interventions, goal informing evidence-based interventions address in cancer.A three-arm was conducted food-insecure (18-item US Department Agriculture Household Security Survey Module score ≥ 3) (N = 117) at four New York City safety net clinics. Arms included a hospital clinic-based...
Abstract BACKGROUND: The objective of this study was to examine the cost effectiveness using a pharmacogenetic test for uridine diphosphate glycosyltransferase 1A1*28 (UGT1A1*28) variant homozygosity before administering irinotecan patients with metastatic colorectal cancer. METHODS: A decision‐analytic model from Medicare payer perspective followed hypothetical who were treated combined 5‐fluorouracil, leucovorin, and irinotecan. Under usual care, received full dose With genetic testing,...
Interventions to address overuse of health care services may help reduce costs and improve care. Understanding physician-level variation behavior patterns can inform such interventions.To assess physician ordering that tend be overused in the treatment patients with cancer. We hypothesized physicians exhibit consistent behavior.Retrospective study 66 years older diagnosed cancer between 2004 2011, using population-based Surveillance, Epidemiology, End Results (SEER)-Medicare data 5...
BACKGROUND The most common, persistent concern among survivors of breast cancer is the fear that their disease will return, yet to authors' knowledge, few interventions targeting recurrence (FCR) have been developed date. current pilot study examined feasibility, acceptability, and preliminary efficacy a home‐delivered cognitive bias modification intervention reduce FCR. intervention, called Attention Interpretation Modification for Fear Breast Cancer Recurrence (AIM‐FBCR), targeted 2 types...
Chemotherapy-induced peripheral neuropathy (CIPN) is a common, debilitating side effect that worsens quality of life and increases the risk falls in cancer survivors. Evidence yoga's safety efficacy treating CIPN lacking.In randomized controlled study, we assigned breast gynecological survivors with persistent moderate-to-severe pain, numbness, or tingling score 4 greater (0-10 numeric rating scale [NRS]) for at least 3 months after chemotherapy to 8 weeks usual care yoga focused on...
Abstract Purpose: Tumor-associated macrophages correlate with increased invasiveness, growth, and immunosuppression. Activation of the colony-stimulating factor-1 receptor (CSF-1R) results in proliferation, differentiation, migration monocytes/macrophages. This phase I study evaluated immunologic clinical activity, safety profile CSF-1R inhibition mAb LY3022855. Patients Methods: advanced refractory metastatic breast cancer (MBC) or castration-resistant prostate (mCRPC) were treated...