Samuel MacKeith

ORCID: 0000-0002-1499-649X
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About
Contact & Profiles
Research Areas
  • Ear Surgery and Otitis Media
  • Vestibular and auditory disorders
  • Hearing, Cochlea, Tinnitus, Genetics
  • Meningioma and schwannoma management
  • Neurofibromatosis and Schwannoma Cases
  • Tracheal and airway disorders
  • Respiratory and Cough-Related Research
  • Hearing Loss and Rehabilitation
  • Essential Oils and Antimicrobial Activity
  • Olfactory and Sensory Function Studies
  • Advanced Chemical Sensor Technologies
  • Glaucoma and retinal disorders
  • Migraine and Headache Studies
  • Facial Nerve Paralysis Treatment and Research
  • Ophthalmology and Eye Disorders
  • Bone Tumor Diagnosis and Treatments
  • Ear and Head Tumors
  • Cerebrospinal fluid and hydrocephalus
  • Fetal and Pediatric Neurological Disorders
  • Cardiovascular Syncope and Autonomic Disorders
  • Vascular Malformations Diagnosis and Treatment
  • Hip disorders and treatments
  • Orthopaedic implants and arthroplasty
  • Musculoskeletal synovial abnormalities and treatments
  • Neurological disorders and treatments

Oxford University Hospitals NHS Trust
2017-2025

John Radcliffe Hospital
2011-2024

University of Oxford
2022

Texas Neurofibromatosis Foundation
2021

University of Cambridge
2018

Addenbrooke's Hospital
2018

Oxford Centre for Computational Neuroscience
2018

Royal Berkshire Hospital
2013-2014

Milton Keynes Hospital
2011-2012

Milton Keynes Hospital NHS Foundation Trust
2011

With the increase in shift pattern work for junior doctors NHS, accurate handover of patient clinical information is great importance. There no published method that forms gold standard and there are large variations practice. This study aims to compare reliability three different methods.We observed 12 simulated patients over five consecutive cycles between SHOs on a one-to-one basis. Three styles were used numerical scoring system assessed lost per cycle.After cycles, only 2.5% was...

10.1308/003588407x168352 article EN Annals of The Royal College of Surgeons of England 2007-03-25

<h3>​Background</h3> The clinical severity of disease in neurofibromatosis type 2 (NF2) is variable. Patients affected with a constitutional truncating <i>NF2</i> mutation have severe disease, while missense mutations or mosaic present milder attenuated phenotype. Genotype-derived natural history data are important to inform discussions on prognosis and management. <h3>Methods</h3> We assessed NF2 phenotype 142 patients relation the UK Genetic Severity Score validate its use as research...

10.1136/jmedgenet-2017-104519 article EN cc-by-nc Journal of Medical Genetics 2017-08-28
D. Gareth Evans Dorothy Halliday Rupert Obholzer Shazia Afridi Claire Forde and 95 more Scott Rutherford Charlotte Hammerbeck-Ward Simon Lloyd Simon Freeman Omar Pathmanaban Owen Thomas Roger Laitt Stavros Stivaros John‐Paul Kilday Grace Vassallo Catherine McBain Timothy Lavin Chay Paterson Gillian Whitfield Martin G. McCabe Patrick Axon Jane Halliday Samuel MacKeith Allyson Parry Patrick Axon Juliette Buttimore James R. Tysome Neil Donnelly Daniele Borsetto James Whitworth Anke Hensiek R. Jena Mathew R. Guilfoyle Richard Mannion James Nicholson Brinda Muthusamy Amy Taylor Richard D. Price Karine Edme Nicola Gamazo Zebunnisa Vanat Daniel Scoffings Josh Scott Sarah Jefferies Richard Knight Tamara Lamb Yu Chuen Tam K. Foweraker Fiona Harris Paul Sanghera Sara Meade Richard Irving Peter Monksfield Nicola Ragge Melanie Murrell Julian Barwell Martin English Rikin Trivedi Shazia Afridi Rosalie E. Ferner Rupert Obholzer Victoria Williams Chris Hammond Karine Lascelles Chris Skilbeck Adam Shaw Angela Swampillai Suki Thomson Nicholas J. Thomas Eleni Maratos Sinan Barazi Rebecca Mullin Susie M.D. Henley Natalie Smith Lal Carlton-Jones Alison Baker Mandy Myers Terry Nunn Charles Nduka Raji Anup Chris Duff Simon Freeman Nicola Jarvis Ian Kamaly-Asl Andrew T. King Mark Kellett John‐Paul Kilday Simon Lloyd Catherine McBain Roger Laitt Martin O’Driscoll Martin G. McCabe Mary Perry Scott Rutherford K. Henshaw Stavros Stivaros Owen Thomas Grace Vassallo Charlotte Hammerbeck-Ward Omar Pathmanaban

Abstract Background Radiation treatment of benign tumors in tumor predisposition syndromes is controversial, but short-term studies from centers suggest safety despite apparent radiation-associated malignancy being reported. We determined whether radiation NF2-related schwannomatosis patients associated with increased rates subsequent (M)/malignant progression (MP). Methods All UK NF2 were eligible if they had a clinical/molecular diagnosis. Cases treated for tumors. Controls matched...

10.1093/noajnl/vdad025 article EN cc-by Neuro-Oncology Advances 2023-01-01

Aims: Macroscopic "gross total resection" was the traditional goal for patients undergoing resection of vestibular schwannoma. There has been a shift toward "subtotal" in an attempt to mitigate risk cranial nerve injury, reserving radiotherapy and/or revision surgery growing residual tumors. The decision subtotal versus may be made preoperatively. Additionally, "near-total" acknowledged as microscopic disease, which is often intraoperatively when encountered. In recent years, some centers...

10.1055/s-0045-1803282 article EN Journal of Neurological Surgery Part B Skull Base 2025-02-01

Accurate and precise measurement of vestibular schwannoma (VS) size is key to clinical management decisions. Linear measurements are used in routine practice but prone error. This study aims compare a semi-automated volume segmentation tool against standard linear method for measuring small VS. also examines whether oblique tumour orientation can contribute Experimental comparison observer agreement using two techniques. Tertiary skull base unit. Twenty-four patients with unilateral sporadic...

10.1007/s00405-018-4865-z article EN cc-by European Archives of Oto-Rhino-Laryngology 2018-01-15

Abstract Objectives: To measure the thermal properties of operative endoscopes used in otorhinolaryngological practice. Methods: A series varying diameters and angulations were attached to a light source temperature measurements taken their shaft tip; measurement was also 5 mm front endoscope tip. Results: Temperature changes took place rapidly. The amount heat produced by maximal at tip, with larger diameter attaining higher temperature. Temperatures on tip reached relatively constant...

10.1017/s0022215107000734 article EN The Journal of Laryngology & Otology 2007-10-17
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