- Essential Oils and Antimicrobial Activity
- Insect Pest Control Strategies
- Allelopathy and phytotoxic interactions
- Parasites and Host Interactions
- Phytochemistry Medicinal Plant Applications
- Helminth infection and control
- Synthesis of heterocyclic compounds
- Insect and Pesticide Research
- Multicomponent Synthesis of Heterocycles
- Research on Leishmaniasis Studies
- Piperaceae Chemical and Biological Studies
- Oral microbiology and periodontitis research
- Phytochemistry and Bioactivity Studies
- Dental Anxiety and Anesthesia Techniques
- Medicinal Plants and Neuroprotection
- Trypanosoma species research and implications
- Molecular spectroscopy and chirality
- Traditional and Medicinal Uses of Annonaceae
- Phytochemical compounds biological activities
- Synthesis and biological activity
- Plant-derived Lignans Synthesis and Bioactivity
- Natural product bioactivities and synthesis
- Parasite Biology and Host Interactions
Universidade de Ribeirão Preto
2022-2024
Universidade de São Paulo
2022-2024
Zero to Three
2022
This study aimed to investigate the chemical composition as well antibacterial, antiparasitic, and cytotoxic potentialities of Brazilian Chrysopogon zizanioides root essential oil (CZ-EO) In addition, CZ-EO cytotoxicity LLCMK2 adherent epithelial cells was assessed. The major compounds identified in were khusimol (30.0 ± 0.3%), β-eudesmol (10.8 α-muurolene (6.0 0.1%), patchouli alcohol (5.6 0.2%). displayed optimal antibacterial activity against Prevotella nigrescens, Fusobacterium...
Chagas disease is a neglected tropical that affects more than 8 million people. Although there are therapies against this disease, the search for new drugs important because current treatments show limited effectiveness and high toxicity. In work, eighteen dihydrobenzofuran-type neolignans (DBNs) two benzofuran-type (BNs) were synthesized evaluated amastigote forms of Trypanosoma cruzi strains. The in vitro cytotoxicity hemolytic activity most active compounds also their relationships with...
The current trend toward using natural food additives, cosmetics, and medicines has motivated industries to substitute synthetic compounds for products. Essential oils (EOs) from medicinal plants are a well-known source of chemical that display several interesting biological activities, including antimicrobial action. In this study, we investigated the antibacterial activity EOs extracted three Piperaceae species collected in Brazilian Amazon region against representative panel cariogenic...
HIGHLIGHTS The sesquiterpene germacrene D was the major constituent in three EOs under investigation. EO from Campomanesia adamantium considered active against Malassezia furfur. All exhibited vitro anti-inflammatory activity by chemotaxis model. most abundant metabolite class of all study formed hydrocarbons.
We have synthesized 22 symmetric and asymmetric 4-aryl-1,4-dihydropyridines (1,4-DHPs) by a “green” microwave-assisted one-pot multicomponent Hantzsch reaction evaluated their cytotoxicity to three human cancer cell lines regarding U-251MG (human glioblastoma), HeLa 229 cervical adenocarcinoma), MCF-7 breast carcinoma). None of the 1,4-DHPs were cytotoxic cells. Most did not affect or viability. On other hand, 18 (diethyl...