- Essential Oils and Antimicrobial Activity
- Natural product bioactivities and synthesis
- Insect Pest Control Strategies
- Piperaceae Chemical and Biological Studies
- Plant Parasitism and Resistance
- Toxin Mechanisms and Immunotoxins
- Phytochemistry Medicinal Plant Applications
- Phytochemistry and Biological Activities
- Research on Leishmaniasis Studies
- Drug Transport and Resistance Mechanisms
- Phytochemical compounds biological activities
- Venomous Animal Envenomation and Studies
- Plant Diversity and Evolution
- Mycorrhizal Fungi and Plant Interactions
- Ethnobotanical and Medicinal Plants Studies
- Erythrocyte Function and Pathophysiology
- Plant tissue culture and regeneration
- Autoimmune Bullous Skin Diseases
- Plant Pathogens and Fungal Diseases
- Carbohydrate Chemistry and Synthesis
- Myxozoan Parasites in Aquatic Species
- Palliative and Oncologic Care
- Skin Protection and Aging
- Bee Products Chemical Analysis
- Medicinal Plants and Neuroprotection
Universidade Federal do Amazonas
2009-2024
Fundação de Amparo à Pesquisa do Estado do Amazonas
2006-2007
Fundação Oswaldo Cruz
2003
Abnormal multiplication of oral bacteria causes dental caries and plaque. These diseases continue to be major public health concerns worldwide, mainly in developing countries. In this study, the chemical composition antimicrobial activity essential oil Vitex agnus-castus leaves (VAC‒EO) collected North Brazil against a representative panel cariogenic were investigated. The VAC-EO was evaluated terms its minimum inhibitory concentration (MIC) values by using broth microdilution method 96-well...
The Myrtaceae family has 121 genera and about 3800 to 5800 species distributed throughout the world, especially in tropical subtropical countries. Many plants this found Amazon region produce essential oils with antioxidant, antimicrobial, antiparasitic activities. In general, from Amazonian of contain substances terpene class, including monoterpene α-pinene sesquiterpene β-caryophyllene, addition phenylpropanoids such as eugenol. However, chemical composition concentration major compounds...
ABSTRACT Introduction Non‐volatile oleoresins from neotropical Burseraceae are traditionally used for craft, technological and medicinal purposes. The crude resin is usually sold in popular markets of the forest communities. Adding value to this rainforest raw material requires establishing its composition. Objective To analyse composition different species establish a minimally reproducible profile by gas chromatography, order parameterise quality control. Methodology Crude oleoresin...
Abstract Objective The Amazon has a rich biodiversity where many different plant species can be found. This diversity is an important source of bioactive substances, mainly due to the structural components their phytometabolites. Research for natural products strategy development new agents in therapeutic applications, especially cosmetic that have better pharmacological potential. Within this perspective, objective study was investigate application (anti‐aging potential) stem‐bark extract...
Abstract The composition of essential oils from two sources oleoresins Protium heptaphyllum were analyzed by GC/MS and Retention Index. the varied according to fresh or aged resin. oil resin was rich in α-terpinene (18.0%), p-cymene (36.0%) γ-terpinene (12.0%), whereas contained (11.0%), terpinolene p-cymen-8-ol (11.0%) dillapiole (16.0%).
The essential oils of Piper marginatum Jacq and callosum Ruiz & Pav were obtained by hydrodistillation tested in vitro against the adult worms Schistosoma mansoni species. chemical constituents evaluated Gas chromatography / Mass spectrometry. main oil leaves P. 3,4- (methylenedioxy) propiophenone (10.41 %), bicyclogermacrene (10.16 %) germacrene D (9.93 %). extraction aerial parts (branches, inflorescences) from provided two oils, one them being transparent greater density than water...
During grain storage, a considerable amount of product is lost because insects, such as Zabrotes subfasciatus. Currently, to mitigate these risks, studies are searching for plants with potential the control agricultural pests, also known botanical insecticides. In this study, fumigant toxicity essential oils Piper callosum (PC-EO), marginatum (PM-EO) and Vitex agnus-castus (VA-EO) against subfasciatus was investigated. The PC-EO, PM-EO VA-EO were analysed by gas chromatography (GC-MS), major...
The current trend toward using natural food additives, cosmetics, and medicines has motivated industries to substitute synthetic compounds for products. Essential oils (EOs) from medicinal plants are a well-known source of chemical that display several interesting biological activities, including antimicrobial action. In this study, we investigated the antibacterial activity EOs extracted three Piperaceae species collected in Brazilian Amazon region against representative panel cariogenic...
Bertholletia excelsais native to the Amazon Rainforest and is popularly known as Brazil nut. It has socioeconomic importance due its nuts being a great export product. There are fewstudies in literature regarding biotechnological potential of bark, although it used folk medicine. The aim this study was determine chemical constituents, anti-inflammatory antioxidant properties B. excelsabark extract(BEB). Twelve substances were identified by LC/MS/MS, cytotoxicity tests carried out, well...
Endophytic fungi were identified from different parts of the medicinal parasitic mistletoe Cladocolea micrantha and its host Anacardium occidentale, suggesting a strict host-parasite relationship. Eight fungal endophytes isolated morphologically characterized. The ascomycete Guignardia mangiferae strains Mycelia sterilia prevalent in isolations. unequivocal identification at probabilistic degree close to 100% was carried out by DNA extraction followed PCR analyses ITS-1 ITS-2 regions...
Eleven known triterpenes (alpha-amyrin, beta-amyrin, lupeol, and their respective acetates, 3-O-acetyl derivatives of betulinic, oleanolic, ursolic acids, cycloartenol, tirucall-7,24-dienol), two new flavonols presenting an uncommon interglycosidic O-(1-->3) linkage (kaempferol 3-O-alpha-L-arabinofuranosyl(1-->3)-alpha-L-rhamnoside quercetin 3-O-alpha-L-arabinofuranosyl-(1-->3)-alpha-L-rhamnoside), beta-sitosterol, stigmasterol, quercetin, gallic acid were isolated from the Amazonian...
O presente estudo apresenta um levantamento completo das espécies epífitas parasitas medicinais famílias Loranthaceae e Viscaeace, conhecidas no Brasil com o nome genérico popular de “erva-de-passarinho”. São apresentados os usos tradicionais descritos na literatura, associados às alguma atividade terapêutica, assim como as substâncias isoladas, listadas por grupos químicos.
Abstract Neutrophils are the first cells recruited to site of an infected sand fly bite and interact with Leishmania parasites. Here we investigate effect salivary proteins on neutrophil recruitment. We purified bone marrow neutrophils from C57BL/6 mice or peripheral blood healthy human dog donors. Chemotaxis driven by saliva vectors visceral (Lutzomyia longipalpis) cutaneous (Phlebotomus duboscqi) disease was measured modified Boyden chamber assay imaging EZTAXIScan assay. migrated towards...
Abstract Neutrophils are the first cells recruited to site of an infected sand fly bite and interact with Leishmania parasites. It has been proposed that recruitment neutrophils increases ability establish infection. Here we investigate effect salivary proteins on neutrophil recruitment. We purified bone marrow from C57BL/6 mice or peripheral blood healthy human donors. Chemotaxis driven by saliva vectors visceral (Lutzomyia longipalpis) cutaneous (Phlebotomus duboscqi) disease was measured...