- Organ Transplantation Techniques and Outcomes
- Pancreatic and Hepatic Oncology Research
- Liver Disease and Transplantation
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease Diagnosis and Treatment
- Gallbladder and Bile Duct Disorders
- Gastric Cancer Management and Outcomes
- Neuroendocrine Tumor Research Advances
- Esophageal and GI Pathology
- Congenital Anomalies and Fetal Surgery
- Metastasis and carcinoma case studies
- Surgical Simulation and Training
- Abdominal Trauma and Injuries
- Renal Transplantation Outcomes and Treatments
- Pediatric Hepatobiliary Diseases and Treatments
- COVID-19 Clinical Research Studies
- Liver physiology and pathology
- Peptidase Inhibition and Analysis
- SARS-CoV-2 detection and testing
- Biliary and Gastrointestinal Fistulas
- Xenotransplantation and immune response
- COVID-19 diagnosis using AI
- Minimally Invasive Surgical Techniques
- Biomedical Research and Pathophysiology
Kyungpook National University
1999-2023
Kyungpook National University Hospital
2004-2022
Kyungpook National University Medical Center
2011-2017
The detoxification capacities of single-pass albumin dialysis (SPAD), the molecular adsorbents recirculation system, (MARS) and continuous veno-venous hemodiafiltration (CVVHDF) were compared in vitro . In each experiment 4,100 mL toxin-loaded human plasma was processed for 6.5 hours. MARS treatment (n = 6) undertaken combination with CVVHDF. For SPAD CVVHDF a high-flux hollow fiber hemodiafilter (identical to filter) used. Levels ammonia, urea, creatinine, bilirubin, bile acids determined....
We performed gene expression profiling of normal and hepatocellular carcinoma (HCC) liver tissues using a high-density microarray that contained 3,063 human cDNA. The results hybridization experiment from eight different HCC were analyzed classified by the Cluster program. Among these differentially-expressed genes, galectin-3, serine/threonine kinase SGK, translation factor eIF- 4A, -4B, -3, fibroblast growth receptor, ribosomal protein L35A up-regulated; mRNAs Nip3, decorin, insulin-like...
The prognosis of the patients with early recurrence after curative hepatectomy for hepatocellular carcinoma (HCC) is usually dismal.One hundred twenty-four underwent resection HCC at Kyungpook National University Hospital from January 2002 to December 2006. An was defined as a within 2 years resection. risk factors associated an were analyzed well other correlated survival recurrence.Early disease developed in 56 (45.2%). tumor size larger than 5 cm (P = 0.001) and presence micrometastasis <...
There is no consensus on the optimal treatment of T1b gallbladder cancer (GBC) due to lack evidence and difficulty anatomy pathological standardization.A total 272 patients with GBC who underwent surgical resection at 14 centers specialized hepatobiliary-pancreatic surgeons pathologists in Korea, Japan, Chile, United States were studied. Clinical outcomes including disease-specific survival (DSS) rates according types surgery analyzed.After excluding patients, 237 qualifying consisted 90 men...
Background The clinical course and viral detection period in mild or asymptomatic coronavirus disease 2019 (COVID-19) patients are not yet known. presumed low diagnostic sensitivity of upper respiratory specimens for Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) makes it difficult to confirm infection recommend de-isolation.
Introduction: Data on the clinical course and duration of viral RNA detection in patients with mild or asymptomatic coronavirus disease 2019 are limited.
 Methodology: In this retrospective analysis, characteristics serial real-time reverse transcriptase-polymerase chain reaction (RT-PCR) results were reviewed a cohort 1186 mildly symptomatic South Korea. Factors associated prolonged RT-PCR positivity for severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) also evaluated....
Anatomic resection (AR) is preferred for eradicating portal tributaries in patients with hepatocellular carcinoma (HCC). However, the extent of influenced by underlying liver disease and tumor location. We compared surgical outcomes recurrence pattern between non-anatomic (NR) AR.From March 2009 to February 2012, 184 underwent HCC. Among these, 79 who were primarily treated a single without rupture or macroscopic vascular invasion enrolled. The divided into 2 groups based on resection: AR...
Backgrounds/Aims Intraductal papillary mucinous neoplasm (IPMN) of the pancreas has malignant potential. Predicting invasive IPMN proven difficult and controversial. We tried to identify predictive factors for IPMN. Methods Thirty six patients underwent resection from February 2001 July 2011. Clinicopathological features including demographic, imaging, microscopic, serological findings were retrospectively reviewed. Receiver operating characteristic (ROC) curve analysis was used analyze...
ERK1 and ERK2 share a great deal of homology have been presumed to similar functions. Available antibodies recognize both isoforms making the elucidation functional differences challenging. Mitogen-activated protein (MAP) kinase networks are commonly depicted in literature as linear sequential phosphorylation cascades; however, activation these pathways is not mutually exclusive. Little doubt exists that MAP kinases engage crosstalk, but extent or direct effect "conversations" unclear. Here,...
Purpose: Biliary tract disease is one of the most common causes acute abdominal pain in elderly patients, but there still some debate over treatment. The aim this study to determine safety and surgical outcomes laparoscopic cholecystectomy (LC) for benign gallbladder octogenarian patients. Methods: We selected 42 patients 80 years or older who underwent LC open-converted cholecystectomy(OC) from February 1992 November 2006. evaluated clinicopathological features, treatment modalities,...
Objectives: Because biliary complications in living donor liver transplantation are most common and troubled problem to transplant surgeons, various method decease has been studied determining the optimal bile duct division point is important decrease complication rate. Intraoperative cholangiogram standard determine for conventional hepatectomy, but laparoscopic indocyanine green (ICG) near-infrared fluorescence alternative option of intraoperative cholangiogram. We compared pure...
Jae Min Chun, M.D., Heontak Ha, Young Yeon Choi, Hyung Jun Kwon, Sang Geol Kim, Yoon Jin Hwang, Hunkyu Ryeom, M.D. and Seok Han, M.D.. J Korean Soc Transplant 2016;30:89-93. https://doi.org/10.4285/jkstn.2016.30.2.89