- Radiomics and Machine Learning in Medical Imaging
- MRI in cancer diagnosis
- Advanced MRI Techniques and Applications
- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease Diagnosis and Treatment
- Lanthanide and Transition Metal Complexes
- Advanced Neuroimaging Techniques and Applications
- Venous Thromboembolism Diagnosis and Management
- Endometrial and Cervical Cancer Treatments
- Medical Imaging and Analysis
- Axon Guidance and Neuronal Signaling
- Acute Ischemic Stroke Management
- Renal cell carcinoma treatment
- Advanced X-ray and CT Imaging
- Functional Brain Connectivity Studies
- Pancreatic and Hepatic Oncology Research
- Trace Elements in Health
- Liver Disease and Transplantation
- Medical Imaging Techniques and Applications
- Cardiac Imaging and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Osteomyelitis and Bone Disorders Research
- Liver physiology and pathology
- Maternal and fetal healthcare
- Aldose Reductase and Taurine
Asan Medical Center
2012-2024
Ulsan College
2008-2022
University of Ulsan
2008-2022
Samsung (South Korea)
2020
Ulsan National Institute of Science and Technology
2014-2019
University of Pittsburgh Medical Center
2011-2013
University of Pittsburgh
2010-2012
Resonance Research (United States)
2012
Research Institute of Radiology
2011
Abstract Purpose To evaluate whether measurement of apparent diffusion coefficient (ADC) and pure ( D ) can help to characterize solid pancreatic masses. Materials Methods Diffusion‐weighted MR imaging was performed in both a patient group n = 71; cancer [ 47], mass‐forming pancreatitis 13], pseudopapillary neoplasm 6], neuroendocrine tumor 5]) normal control 11) by applying three b‐factors 0, 500, 1000 sec/mm 2 . ADC 500 , (ADC using b ), perfusion fraction f 1‐ exp [‐500 × – )]) pancreas,...
To assess the correlation between volumetric measurements of clot, semiquantitative clot burden indexes, and signs right heart dysfunction at computed tomographic (CT) pulmonary angiography in patients with acute embolism (PE) to determine whether are associated short-term mortality.This retrospective study was institutional review board approved HIPAA compliant. CT angiographic studies (January 2007 through December 2007) findings positive for PE were retrieved. Two readers evaluated...
Abstract Purpose To investigate the feasibility of diffusion‐weighted imaging (DWI) in differentiation metastatic from nonmetastatic lymph nodes. Materials and Methods In 125 patients who underwent node dissection for uterine cervical cancer, DWI was performed at b value 0 1000 s/mm 2 . By referring to surgical maps pelvic nodes, apparent diffusion coefficient (ADC) compared receiver‐operating‐characteristics analysis evaluate diagnostic performance ADC differentiating Results The were...
To prospectively evaluate the reproducibility of apparent diffusion coefficient (ADC) measurement in malignant hepatic tumors and to examine influence imaging methods, lesion location, size on ADC measurement.The institutional review board approved study protocol, informed consent was obtained. Forty-nine patients underwent both breath-hold respiratory-triggered diffusion-weighted (DW) magnetic resonance a 1.5-T system twice. Two independent readers measured largest tumor for each patient...
Purpose To develop and validate a radiomics-based model for staging liver fibrosis by using gadoxetic acid–enhanced hepatobiliary phase MRI. Materials Methods In this retrospective study, 436 patients (mean age, 51 years; age range, 18–86 319 men [mean years]; 117 women 50 18–79 years]) with pathologic analysis–proven who underwent MRI from June 2015 to December 2016 were randomized in three-to-one ratio into development (n = 329) test 107) cohorts, respectively. the cohort, was developed...
Abstract Purpose To evaluate diagnostic performance of apparent diffusion coefficient (ADC) in differentiating prostate cancer from noncancerous tissue according to anatomical region. Materials and Methods In 47 patients with diffusion‐weighted‐MR (b‐value, 0 1000 sec/mm 2 ) on a 1.5 T unit, ADCs were measured three tissues (transitional zone, peripheral prostatic base). Diagnostic ADC for was evaluated using receiver‐operating‐characteristics (ROC) analysis. Results Mean (0.963 × 10 −3 mm...
Abstract Purpose To determine the reference site for relative apparent diffusion coefficient (rADC) and to evaluate benefit of rADC detecting metastatic lymph nodes in uterine cervical cancer. Materials Methods Two observers independently measured ADCs spleen, liver, renal cortex, lumbar spine, spinal cord, gluteus maximus on diffusion‐weighted images (b value, 0 1000 mm/sec 2 ) 50 patients. The was determined using intra‐ interobserver variation (CV) ADC these organs. calculated by lesion...
Abstract Purpose: To evaluate the effect of diffusion‐weighted imaging (DWI) methods, apparent diffusion coefficient (ADC) calculation and selection b‐values on ADCs measurement reproducibility malignant hepatic tumors. Materials Methods: Nineteen patients with pathologically confirmed tumors underwent breath‐hold DWI (b‐values = 0, 50, 500 s/mm 2 ) respiratory‐triggered (0, 300, 500, 1000 twice a 1.5 T magnetic resonance (MRI) scanner. were calculated using two b‐value and/or multiple...
To evaluate the performance of a semi-automated method for segmentation individual renal cysts from magnetic resonance (MR) images in patients with autosomal dominant polycystic kidney disease (ADPKD).
OBJECTIVE. The purpose of this article is to quantitatively assess the rate resolution clot burden detected on pulmonary CT angiography (CTA) in patients with acute embolism (PE).
Scientific Report17 September 2018free access Source DataTransparent process Netrin-1/DCC-mediated PLCγ1 activation is required for axon guidance and brain structure development Du-Seock Kang orcid.org/0000-0002-3688-1087 School of Life Sciences, Ulsan National Institute Science Technology, Ulsan, Korea College & Bioengineering, Advanced Technology (KAIST), Daejeon, Search more papers by this author Yong Ryoul Yang Cheol Lee BumWoo Park Kwang IL Jeong Kon Seo UNIST Central Research Facility,...
Abstract The isotope effect is studied in the magneto‐electroluminescence (MEL) and pulsed electrically detected magnetic resonance of organic light‐emitting diodes based on thermally activated delayed fluorescence (TADF) from donor–acceptor exciplexes that are either protonated (H) or deuterated (D). It found at ambient temperature, exchange H to D has no spin‐dependent current MEL responses devices. However, cryogenic temperatures, where reverse intersystem crossing (RISC) triplet singlet...
We aimed to develop and test a deep learning algorithm (DLA) for fully automated measurement of the volume signal intensity (SI) liver spleen using gadoxetic acid-enhanced hepatobiliary phase (HBP)-magnetic resonance imaging (MRI) evaluate clinical utility DLA-assisted assessment functional capacity.The DLA was developed HBP-MRI data from 1014 patients. Using an independent dataset (110 internal 90 external MRI data), segmentation performance measured Dice similarity score (DSS), agreement...
The purpose of this study was to compare quantitative and visual assessments regional heterogeneity emphysema investigate the influence on pulmonary function in smoking-related emphysema.We developed an automatic computerized algorithm quantitatively assess upper-lower, anterior-posterior, central-peripheral directions. index plotted with a linear (emphysema slopes: slope upper-lower direction, anterior-posterior direction) for consecutive 1-pixel-thick slices using volumetric CT data 59...
Oxidative stress is a key mediator of neuronal death in acute brain injuries, such as epilepsy, trauma, and stroke. Although it accompanied by diverse cellular changes, increases levels intracellular zinc ion (Zn2+) calcium (Ca2+) may play critical causative role oxidative death. However, the mechanistic link between Zn2+ Ca2+ dyshomeostasis neurons during not well-understood. Here, we show that exposure cortical to H2O2 led zinc-triggered influx, which resulted The cyclin-dependent kinase...
The purpose of our study was to assess the accuracy and reproducibility clot burden quantification with pulmonary CT angiography (CTA).A semiautomated program developed for segmentation volumetric embolus CTA. this measurement method assessed using two phantoms. Reproducibility clinical CTA in 30 patients (16 women, 14 men; mean age, 62 years) embolism (PE). Two observers segmented measured volume blood from images twice at separate sessions. Accuracy evaluated by relative error. Intra-...