A5072877743- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Corneal surgery and disorders
- Ophthalmology and Eye Disorders
- Ophthalmology and Visual Impairment Studies
- Optical Coherence Tomography Applications
- Cerebral Venous Sinus Thrombosis
- Ocular Surface and Contact Lens
- Retinal and Optic Conditions
- Retinal and Macular Surgery
- Neurological Disorders and Treatments
- Retinal Development and Disorders
- Intraocular Surgery and Lenses
- Ocular Oncology and Treatments
- Older Adults Driving Studies
- Traffic and Road Safety
- Cerebrovascular and Carotid Artery Diseases
- Corneal Surgery and Treatments
- Healthcare and Venom Research
- Ophthalmology and Visual Health Research
- Proteoglycans and glycosaminoglycans research
- Ergonomics and Musculoskeletal Disorders
- Visual perception and processing mechanisms
- Retinopathy of Prematurity Studies
Dalhousie University
2016-2025
Nova Scotia Health Authority
2019-2023
Foundation Fighting Blindness
2023
Health Sciences Centre
2022
Capital District Health Authority
2013-2014
Queen Elizabeth II Health Sciences Centre
2012-2013
Universidade de São Paulo
1994-2012
North Toronto Eye Care
2003
Universidade Federal de São Paulo
2003
University of Miami
1998-2002
We previously demonstrated that most eyes have regionally variable extensions of Bruch's membrane (BM) inside the clinically identified disc margin (DM) are and photographically invisible. studied impact these findings on DM- BM opening (BMO)-derived neuroretinal rim parameters.Disc stereo-photography spectral domain optical coherence tomography (SD-OCT, 24 radial B-scans centered optic nerve head) were performed 30 glaucoma patients 10 age-matched controls. Photographs colocalized to SD-OCT...
purpose. To investigate the risk of falls and motor vehicle collisions (MVCs) in patients with glaucoma. methods. The sample comprised 48 glaucoma (mean visual field mean deviation [MD] better eye = −3.9 dB; 5.1 dB SD) 47 age-matched normal control subjects, who were recruited from a university-based hospital care clinic are enrolled an ongoing prospective study factors for falls, MVCs, on-road driving performance Main outcome measures at baseline previous self-reported police-reported MVCs....
Purpose.: To determine the rate of glaucomatous visual field change in routine clinical care.
To investigate the on-road driving performance of patients with glaucoma.The sample comprised 20 glaucoma and subjects normal vision, all licensed drivers, matched for age sex. Driving was tested over a 10-km route incorporating 55 standardized maneuvers skills through residential business districts Halifax, Nova Scotia, Canada. Testing conducted by professional instructor assessed an occupational therapist certified in driver rehabilitation, masked to participant group membership level...
To compare test results from second-generation Frequency-Doubling Technology perimetry (FDT2, Humphrey Matrix; Carl-Zeiss Meditec, Dublin, CA) and standard automated (SAP) in patients with glaucoma. Specifically, to examine the relationship between visual field sensitivity test-retest variability total pattern deviation probability maps both techniques.Fifteen glaucoma who had early moderately advanced loss SAP (mean MD, -4.0 dB; range, +0.2 -16.1) were enrolled study. Patients attended...
Objective: To investigate the efficacy and safety of adjunctive mitomycin when used during a primary trabeculectomy within series 89 consecutive patients at 1 2 years postoperatively.Design: A cohort study all who underwent trabeculectomy, performed by one us (P.F.P.), between April 1, 1991, December 31, 1994.Patients received topical in conjunction with corneal valve incision.A was considered "successful" if it resulted an intraocular pressure (IOP) 21 mm Hg or lower 30% greater reduction...
To determine rates of visual field change associated with risk factors for progression in the Canadian Glaucoma Study (abnormal anticardiolipin antibody level, age, female sex, and mean follow-up intraocular pressure [IOP]), to evaluate effect IOP reduction on subsequent progressing patients.Two hundred sixteen patients (median 65.2 years) were followed up at 4-month intervals perimetry monitored progression. Patients reaching an end point based total deviation analysis underwent 20% or...
To study changes in lamina cribrosa position and prelaminar tissue thickness (PTT) after surgical IOP reduction glaucoma patients.Twenty-two patients (mean age, 71.4 years) were imaged with spectral domain optical coherence tomography (SD-OCT; 24 radial B-scans centered on the optic nerve head [ONH]) before trabeculectomy or tube shunt implantation. Follow up images acquired 1 week, month, 3 months, 6 months postsurgery. Bruch's membrane opening (BMO), internal limiting (ILM) anterior...
Purpose.: To compare the properties of visual field index (VFI) to those mean deviation (MD) in patients with glaucoma. Methods.: MD and VFI were calculated data obtained from an ongoing longitudinal study which glaucoma (N = 109, 204 eyes) observed for 9.8 years (median, 21 tests) static automated perimetry. compared one test each eye, a subset 30 tests selected judgments eight experts who judged percentage remaining field. In series over time, rates change, statistical significance,...
To examine peripapillary choroidal thickness in healthy controls and patients with glaucoma who have focal, diffuse, sclerotic optic disc damage.Healthy (n=92) focal (n=34), diffuse (n=35), (n=34) damage were imaged spectral-domain optical coherence tomography (12° circular scan protocol centered on nerve head). Peripapillary was measured as the distance between automatically segmented retinal pigment epithelium/Bruch's membrane manually outlined interface posterior choroid anterior border...
To evaluate the intraocular pressure (IOP)-lowering efficacy and safety of 10 15 µg bimatoprost implant in patients with open-angle glaucoma (OAG) or ocular hypertension (OHT). This randomized, 20-month, multicenter, masked, parallel-group, phase 3 trial enrolled 528 OAG OHT an open iridocorneal angle inferiorly study eye. Study eyes were administered on day 1, week 16, 32, twice-daily topical timolol maleate 0.5%. Primary endpoints IOP change from baseline through 12. Safety measures...
Vasospasm has been associated with glaucoma, but its mechanisms have not elucidated. The present study was designed to evaluate the role of endothelin (ET)-1, a potent endogenous vasoconstrictor, in genesis vasospasm glaucoma.Our sample contained patients open-angle glaucoma (n = 43) and subjects normal nonglaucomatous eyes without acral 27). After eligibility visit, all underwent provocative cooling test, consisting wearing for 30 minutes head-vest garment containing coolant fluid. Blood...
To compare visual field progression with total and pattern deviation analyses in a prospective longitudinal study of patients glaucoma healthy control subjects.A group 101 (168 eyes) early to moderately advanced loss at baseline (average mean [MD], -3.9 dB) no clinical evidence media opacity were selected from on glaucoma. Patients examined static automated perimetry 6-month intervals for median follow-up 9 years. At each test location, change was established event trend deviation. The...