A5050501153- Immune Cell Function and Interaction
- 3D Printing in Biomedical Research
- Cellular Mechanics and Interactions
- Malaria Research and Control
- Asymmetric Synthesis and Catalysis
- Atherosclerosis and Cardiovascular Diseases
- T-cell and B-cell Immunology
- Ginseng Biological Effects and Applications
- ATP Synthase and ATPases Research
- Synthetic Organic Chemistry Methods
- Cancer, Hypoxia, and Metabolism
- Medical Imaging and Analysis
- Planarian Biology and Electrostimulation
- Advanced Neuroimaging Techniques and Applications
- Immunotherapy and Immune Responses
- Laser Applications in Dentistry and Medicine
- Viral Infections and Vectors
- Parasitic Diseases Research and Treatment
- Marine Sponges and Natural Products
- Scoliosis diagnosis and treatment
- Glutathione Transferases and Polymorphisms
- vaccines and immunoinformatics approaches
- Spine and Intervertebral Disc Pathology
- Macrophage Migration Inhibitory Factor
- Pharmacological Effects of Natural Compounds
Gyeongsang National University
2024-2025
Seoul National University Hospital
2024
Seoul National University
2017-2021
Pusan National University
2011-2021
Georgia State University
2014
Kangwon National University
1999-2001
The application of light-emitting diode (LED)-dependent photobiomodulation (PBM) in promoting post-tendon injury healing has been recently reported. Despite establishing a theoretical basis for ligament restoration through PBM, identifying effective LED wavelength combinations and ensuring safety animal models remain unresolved challenges. In our previous study, we demonstrated that combined irradiation at 630 nm 880 promotes cell proliferation migration, which are critical processes during...
Among diverse helper T-cell subsets, Th17 cells appear to be pathogenic in autoimmune diseases, and thus, targeting could beneficial for the treatment of diseases humans. Ginsenoside Rg3 is one most potent components Korean Red Ginseng (KRG; Panax ginseng Meyer) ameliorating inflammatory responses. However, role Th17-mediated autoimmunity unclear. We found that significantly inhibited differentiation from naïve precursors a dendritic cell (DC)–T co-culture system. While minimally affected...
Abstract Pathogenic conversion of Th17 cells into multifunctional helper T or Th1 contributes to the pathogenesis autoimmune diseases; however, mechanism regulating plasticity remains unclear. Here, we found that expressed latent TGF-β1 in a manner dependent on autocrine TGF-β1. By employing IL-17-producing cell-specific Tgfb1 conditional knockout and fate-mapping systems, demonstrated TGF-β1-deficient are relatively susceptible becoming IFN-γ producers through IL-12Rβ2 IL-27Rα upregulation....
Korean Red Ginseng (KRG; Panax ginseng Meyer) is a widely used medicinal herb known to exert various immune modulatory functions. KRG and one of its purified components, ginsenoside Rg3, are possess anti-inflammatory activities. How they impact helper T cell-mediated responses not fully explored. In this study, we attempted evaluate the effect extract (KRGE) Rg3 on Th1 cell responses. Using well-characterized in vitro differentiation systems, examined effects KRGE or enhanced Th1-inducing...
This study assessed automated bone density measurement technologies in pediatric groups, focusing on lumbar spine localization and segmentation models initially trained adult data. The research involved three phases: training using YOLOv5 U-Net images, adapting these with data via transfer learning, external validation categorized by age to account for anatomical variances. adult-trained model showed decreased sensitivity younger ages, the lowest performance youngest group. Conversely,...
Ling Jin, Minkyoung Cho, Bo-Sung Kim, Jung Ho Han, Sungmi Park, In-Kyu Lee, Dongryeol Ryu, Jae Sung-Jin Bae & Ki-Tae Ha. BMB Reports 2021;54:563-8. https://doi.org/10.5483/BMBRep.2021.54.11.101
Neurogenesis can be induced by pathological conditions such as cerebral ischemia. However the molecular mechanisms or modulating reagents of reactive neurogenesis after ischemia are poorly characterized. Retinoic acid (RA) has been shown to increase enhancing proliferation and neuronal differentiation forebrain neuroblasts. Here, we examined whether RA modulate In contrast our expectation, treatment decreased in subventricular zone (SVZ), subgranular (SGZ) penumbral region. Furthermore, also...
An important paradigm in 3D object detection is the use of multiple modalities to enhance accuracy both normal and challenging conditions, particularly for long-tail scenarios. To address this, recent studies have explored two directions adaptive approaches: MoE-based fusion, which struggles with uncertainties arising from distinct configurations, late fusion output-level relies on separate pipelines limits comprehensive understanding. In this work, we introduce Cocoon, an object-...
Galectins are generally believed to be potential candidates for use in the development of novel antiinflammatory agents or as selective modulators immune response. In particular, galectin-9 exhibits some extracellular functions, including cell aggregation, adhesion, chemoattraction, activation, and apoptosis. Tl-galectin (Tl-gal, homologue gene) was isolated from an adult worm Toxascaris leonina. The full-length Tl-gal gene, which incorporated into pET-28a, overexpressed E. coli purified by...
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at glance that was extracted from about 100 leading journals. To access of an article which published elsewhere, please select “Full Text” option. The original trackable via the “References”
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at glance that was extracted from about 100 leading journals. To access of an article which published elsewhere, please select “Full Text” option. The original trackable via the “References”