A5017749040- Colorectal Cancer Surgical Treatments
- Colorectal and Anal Carcinomas
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Screening and Detection
- Anorectal Disease Treatments and Outcomes
- Diverticular Disease and Complications
- Colorectal Cancer Treatments and Studies
- Stoma care and complications
- Genetic factors in colorectal cancer
- Radiomics and Machine Learning in Medical Imaging
- Cardiac, Anesthesia and Surgical Outcomes
- Clinical practice guidelines implementation
- Bladder and Urothelial Cancer Treatments
- Cancer-related molecular mechanisms research
- Multiple and Secondary Primary Cancers
- Metastasis and carcinoma case studies
- Head and Neck Surgical Oncology
- Tumors and Oncological Cases
- Glioma Diagnosis and Treatment
- Prostate Cancer Diagnosis and Treatment
- Brain Metastases and Treatment
- Circular RNAs in diseases
- Radiopharmaceutical Chemistry and Applications
- Cancer Research and Treatments
- MRI in cancer diagnosis
Peking Union Medical College Hospital
2015-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2015-2024
Union Hospital
2021-2022
Academy of Medical Sciences
2014-2022
The extent of lymphadenectomy during laparoscopic right colectomy can affect the oncological outcome and safety surgery. principle complete mesocolic excision (CME) has been gradually accepted increasingly applied by colorectal surgeons. aim this study is to investigate whether extended in could improve outcomes patients with right-sided colon cancers, compared D2 lymphadenectomy. Radical Extent lympadenectomy: dissection versus LAparoscopic Right Colectomy for cancer (RELARC) a prospective,...
There is concern regarding the possibility of postoperative complications for laparoscopic right colectomy.
Transanal total mesorectal excision (taTME) has recently emerged as a promising novel surgical procedure for rectal cancer. It is believed to hold the potential advantage of providing better access mobilize distal rectum and achieving pathologic results. This study aimed evaluate feasibility taTME cancer summarize preliminary experience in 10 Chinese hospitals.A 211 patients were enrolled this study. Variables evaluation safety, feasibility, oncologic outcomes retrospectively collected...
Our aim was to compare short- and long-term oncological outcomes between laparoscopic open colectomy in T4 colon cancer.We retrospectively analysed of 94 patients who underwent surgery December 2010 2016 for pT4 cancer, with propensity score matching. All were treated curative intent, by either or en bloc resection.The conversion rate the group 17.0%. Blood loss, time flatus postoperative hospitalization significantly less group. Postoperative morbidity mortality within 30 days did not...
Introduction: People with metastatic gastric cancer (GC) have a poor prognosis. The study aims to investigate the efficacy of multi-modality treatment for patients GC. Methods: We retrospectively identified 267 stage IV who were treated systemic chemotherapy: 114 received treatments, 153 systematic chemotherapy alone. survival these two groups was compared by log rank test, independent prognostic factors investigated using univariate and multivariate analyses. Results: median GC...
Both loop ileostomy (LI) and transverse colostomy (LTC) could achieve absolute fecal diversion have several advantages. This study compared LI LTC following laparoscopic low anterior resection for rectal cancer after neoadjuvant chemoradiotherapy.Between January 2009 December 2016, 186 patients who underwent ostomy were included. All received preoperative chemoradiotherapy. Of these, 77 109 LTC. Demographic characteristics, operative details, complications analyzed.In the period, group...
Platelet-derived growth factor receptor (PDGFR) signaling pathway was involved in the progress of colorectal cancer (CRC).By using bioinformatic system online, we found that PDGFRα is a potential target miR-219-5p.However, expression pattern and underlying mechanisms miR-219-5p had not been elucidated CRC.Herein, first evaluated tumor tissues by real-time polymerase chain reaction.Next, confirmed luciferase report.And then, investigated biological functions vitro cell proliferation apoptosis...
This study was to compare the prevalence of stoma-related complications and stoma reversal perioperative patients with low-lying rectal cancer who received preventative loop ileostomy those underwent transverse colostomy.This retrospective single-center analyzed clinicopathologic surgical data 288 pathologically proven primary anterior resection either (n = 82) or colostomy. To achieve comparability a propensity score matching method used match from each group in 1:2 ratio. Determinants were...
Background:The purpose of this study was to assess the efficacy and safety rectal modular dissection (RMD) in male patients with middle low cancer.RMD is a technique used guide surgical procedure for mobilization, ultimate goal achieving total mesorectal excision.In order evaluate effectiveness RMD, single-center, non-inferiority randomized clinical trial carried out.Methods: Eligible were randomly assigned into two groups: RMD group traditional mobilization (TRM) group.Demographic...
3544 Background: Signet-ring cell carcinoma (SRCC) of the rectum and sigmoid colon is a rare highly malignant challenge in clinical practice. Although high PD-1+CD8+ tumor-infiltrating lymphocyte (TIL) infiltration has been reported as positive prognostic factor gastric cancer, pancreatic etc., its role colorectal SRCC remains unclear. This study aims to explore immune landscape implications. Methods: The included 34 patients with stage II-IV colon. contextures tumor tissues were...
To investigate the clinical characteristics of brain metastases after radical surgery for locally advanced rectal cancer (LARC).
Objective: To investigate whether protective colostomy and ileostomy have different impact on anastomotic leak for rectal cancer patients after neoadjuvant chemoradiotherapy (nCRT) radical surgery. Methods: A retrospectively cohort study was conducted. Inclusion criteria: (1) Standard therapy before operation; (2) Laparoscopic resection performed; (3) During the operation, enterostomy performed including transverse ileostomy; (4) The were followed up regularly; (5) Clinical data complete....
e15616 Background: Following neoadjuvant chemoradiotherapy (nCRT), total mesorectal excision surgery used to be the standard therapy for locally advanced rectal cancer (LARC). However, radical is associated with high complication rates and impairs patients' quality of life, especially non-sphincter preservation procedures. For past two decades, nCRT followed by organ strategies like watch-and-wait (W&W) or local resection offers an alternative patients being clinically evaluated complete...
To explore the impact on safety and prognosis in patients with right-sided colon cancer participating surgical clinical research.
To evaluate the feasibility, short- and long-term outcomes, safety of laparoscopic resection for advanced colorectal cancer (CRC) in solid organ transplant recipients.Between September 2001 April 2016, five patients who underwent laparoscopic-assisted CRC after transplantation were included this study. Their clinical data retrospectively analyzed with regard to patient demographics, immunosuppressive therapy, tumor characteristics, surgical follow-up data.Four kidney one heart recipients...
Background: Previous studies have described diversities in biology and prognosis for colon cancer based on whether the primary is right-sided or left-sided. Recently, there an ongoing debate as to tumor location itself represents independent prognostic factor. We aimed evaluate clinicopathologic features survival between (RCC) left-sided (LCC) stage III cancer.