- Advanced Radiotherapy Techniques
- Advances in Oncology and Radiotherapy
- Breast Cancer Treatment Studies
- Lung Cancer Diagnosis and Treatment
- Global Cancer Incidence and Screening
- Economic and Financial Impacts of Cancer
- Cancer survivorship and care
- Radiation Dose and Imaging
- Palliative Care and End-of-Life Issues
- Chemotherapy-induced cardiotoxicity and mitigation
- Cardiac Imaging and Diagnostics
- Lung Cancer Treatments and Mutations
- Radiomics and Machine Learning in Medical Imaging
- Health Systems, Economic Evaluations, Quality of Life
- Cardiovascular Function and Risk Factors
- Clinical practice guidelines implementation
- Medical Imaging Techniques and Applications
- Breast Lesions and Carcinomas
- AI in cancer detection
- Endometrial and Cervical Cancer Treatments
- Patient-Provider Communication in Healthcare
- Childhood Cancer Survivors' Quality of Life
- Breast Implant and Reconstruction
- Cancer Genomics and Diagnostics
- Management of metastatic bone disease
UNSW Sydney
2016-2025
Liverpool Hospital
2016-2025
South Western Sydney Local Health District
2016-2025
Ingham Institute
2016-2025
Cancer Australia
2010-2024
The University of Sydney
2015-2023
Sciences, Philosophie, Histoire
2023
Migration Institute of Australia
2022
Macquarie University
2020
Camden and Campbelltown Hospitals
2006-2020
Abstract Radiotherapy utilization rates for cancer vary widely internationally. It has previously been suggested that approximately 50% of all patients should receive radiation. However, this estimate was not evidence‐based. The aim study to the ideal proportion new cases radiotherapy at least once during course their illness based on best available evidence. An optimal tree constructed each upon indications taken from evidence‐based treatment guidelines. with clinical attributes indicated a...
To determine the clinical utility of intrinsic molecular phenotype after breast-conserving therapy (BCT) with lumpectomy and whole-breast irradiation or without a cavity boost.Four hundred ninety-eight patients invasive breast cancer were enrolled into randomized trial BCT tumor bed radiation boost. Tumors classified by as luminal A B, HER-2, basal-like, unclassified using five-biomarker panel: estrogen receptor, progesterone CK5/6, epidermal growth factor receptor. Kaplan-Meier Cox...
A major challenge in value-based health care is the lack of standardized outcomes measurements, hindering optimal monitoring and comparison quality across different settings globally. The International Consortium for Health Outcomes Measurement (ICHOM) assembled a multidisciplinary international working group, comprised 26 providers patient advocates, to develop standard set patient-centered breast cancer (BC). group convened via 8 teleconferences completed follow-up survey after each...
Management of patients with ductal carcinoma in situ (DCIS) is a dilemma, as mastectomy provides nearly 100% cure rate but at the expense physical and psychologic morbidity. It would be helpful if we could predict which DCIS are sufficiently high risk local recurrence after conservative surgery (CS) alone to warrant postoperative radiotherapy (RT) sufficient CS + RT mastectomy. The authors reviewed published studies identified factors that may predictive management by mastectomy, alone, or...
Background Proposed causes for increased mortality following weekend admission (the ‘weekend effect’) include poorer quality of care and sicker patients. The aim this study was to analyse the 7 days post-admission time patterns excess identify whether distinct exist patients depending upon relative contribution (care effect) or a case selection bias presenting on weekends (patient effect). Methods Emergency department admissions all 501 hospitals in New South Wales, Australia, between 2000...
Despite accumulating evidence indicating that collecting patient-reported outcomes (PROs) and transferring results to the treating health professional in real time has potential improve patient well-being cancer outcomes, this practice is not widespread.The aim of study was test feasibility acceptability PROMPT-Care (Patient Reported Outcome Measures for Personalized Treatment Care), a newly developed electronic (eHealth) system facilitates PRO data capture from patients, linkage retrieval...
Abstract Aim Clinical trials play a critical role in advancing cancer care, but international research shows that few patients, particularly culturally and linguistically diverse (CALD) participate trials. This limits generalizability of trial results increases health disparities. study aimed to establish rates correlates participation among CALD patients South Western Sydney Local Health District (SWSLHD), highly area. Methods Data from all diagnosed and/or treated SWSLHD January 2006 July...
Background Despite the acceptability and efficacy of e–patient-reported outcome (ePRO) systems, implementation in routine clinical care remains challenging. Objective This pragmatic trial implemented PROMPT-Care (Patient Reported Outcome Measures for Personalized Treatment Care) web-based system into existing workflows evaluated its effectiveness among a diverse population patients with cancer. Methods Adult solid tumors receiving active treatment or follow-up four cancer centers were...
Radiotherapy for thoracic and breast tumours is associated with a range of cardiotoxicities. Emerging evidence suggests cardiac substructure doses may be more predictive specific outcomes, however, quantitative data necessary to develop clinical planning constraints lacking. Retrospective analysis patient required, which relies on accurate segmentation substructures. In this study, novel model was designed deliver reliable, accurate, anatomically consistent 18 substructures computed...
Abstract BACKGROUND Radiotherapy utilization rates for breast carcinoma vary widely, both within and between countries. Current estimates of the proportion patients with who optimally should receive radiotherapy are based either on expert opinion or measurement actual rates, not best scientific evidence. METHODS To develop an evidence‐based benchmark in carcinoma, authors undertook a systematic review treatment guidelines use carcinoma. A decision tree was constructed, proportions clinical...
Multidisciplinary meetings (MDMs) are increasingly being mandated as essential to oncology practice. However, there is a paucity of data on their effectiveness. The aim this study was assess whether MDM recommendations were concordant with guidelines in the treatment lung cancer.The Lung Cancer Meeting South West Sydney, Australia, prospectively collects all patients whose cases have been presented. New cancer who presented between December 1, 2005, and 31, 2007, reviewed. Patients assigned...