- MRI in cancer diagnosis
- Advanced MRI Techniques and Applications
- HER2/EGFR in Cancer Research
- Monoclonal and Polyclonal Antibodies Research
- Cancer-related gene regulation
- Radiopharmaceutical Chemistry and Applications
- Ovarian cancer diagnosis and treatment
- Retinal and Macular Surgery
- Esophageal Cancer Research and Treatment
- Peripheral Neuropathies and Disorders
- Glaucoma and retinal disorders
- NMR spectroscopy and applications
- Hereditary Neurological Disorders
- Renal cell carcinoma treatment
- Advanced Neuroimaging Techniques and Applications
- Peripheral Nerve Disorders
- Characterization and Applications of Magnetic Nanoparticles
- Advanced X-ray Imaging Techniques
- Colorectal Cancer Surgical Treatments
- Retinal Imaging and Analysis
- Corneal Surgery and Treatments
- Atomic and Subatomic Physics Research
- Obstructive Sleep Apnea Research
- Dermatology and Skin Diseases
- Colorectal and Anal Carcinomas
Sichuan University
2023
West China Hospital of Sichuan University
2023
Shandong Provincial QianFoShan Hospital
2019-2023
Shandong First Medical University
2023
Canadian Nuclear Laboratories
2023
University of Ottawa
2023
Peking University Shenzhen Hospital
2020-2022
Hong Kong University of Science and Technology
2020-2022
University of Hong Kong - Shenzhen Hospital
2020-2022
Nankai University
2022
Chronic inflammatory demyelinating polyradiculoneuropathy is an autoimmune disease characterized by recurrent demyelination and remyelination with resultant thickening of the peripheral nerves. We report a case in which sonography was instrumental demonstrating diffuse nerve hypertrophy. On sonography, both brachial plexuses were found to be diffusely hypertrophic hypoechoic. Similar findings noted for median, sciatic, femoral The plexus confirmed MRI. © 2000 John Wiley & Sons, Inc. J Clin...
Abstract Magnetic resonance (MR) phase‐difference methods work well for measuring volumetric flow rates when the vessel diameter is large compared with in‐plane voxel dimensions. For small vessels (eg, coronary arteries), partial‐volume effects introduce substantial errors in measured volume rate. To correctly measure through a voxel, both fraction of containing moving spins and phase shift imparted to those must be known. The authors propose measurement method that combines information...
Han-Mei Zhang, Da-Guang Wen, Jie Chen, Yun-Tian Meng Yin, Yi Wang, Wei, Yi-Ge Bao, Ying-Hua Wu, Bin Song
Objective: To examine the potential of intravoxel incoherent motion (IVIM) and blood oxygen level-dependent (BOLD) magnetic resonance imaging for detecting renal changes after iodinated contrast-induced acute kidney injury (CI-AKI) development in a diabetic rabbit model.Materials Methods: Sixty-two rabbits were randomized into 2 groups: with contrast agent (DCA) healthy (NCA).In each group, 6 underwent IVIM BOLD at 1 hour, day, days, 3 4 days an iohexol injection while 5 selected to undergo...
The perceived acuity of intracerebral hemorrhage (ICH) impacts the management patients, both within emergent and outpatient/urgent settings. Morphology enabled dipole inversion (MEDI) quantitative susceptibility imaging (QSM) has improved characterization ICH acuity, despite outstanding limitations in distinguishing blood products.Using quantification, novel postprocessing QSM method from multiecho complex total field (mcTFI) may better discriminate between acute subacute ICH, compared to...
Magnetization prepared segmented acquisition requires a view order that maximizes signal contrast during the of central portion k-space. Steady state free precession (SSFP) further minimizes changes in phase-encoding gradients from one repetition to next minimize eddy current artifacts. In this article, optimal ordering schemes satisfying these two requirements are formulated and applied inversion 3D SSFP contrast-enhanced MR angiography (MRA). Experiments on phantoms pigs demonstrated...
To evaluate the targeting property in vitro and vivo of two tumor-associated glycoprotein 72 (TAG-72) binding peptides, previously identified this laboratory by phage selection using different elution conditions.The peptides GGVSCMQTSPVCENNL (A2-6) NPGTCKDKWEICLLNGG (A3-10) were radiolabeled with technetium-99m ((99m)Tc) N-hydroxysuccinimidyl-S-acetyl-mercaptoacetyltriglycine (NHS-MAG(3)) as a chelator or biotinylated. The specificity for TAG-72 positive LS-174T cancer cells was demonstrated...
A technique is described for angiographic imaging of the renal arteries with acquisition performed over several periods suspended respiration. The 3D Fourier transform (FT) gradient-echo sequence uses magnetization preparation and appropriately chosen delay times background nulling time-of-flight enhancement vasculature. was applied to 10 volunteers, each whom imaged in three ways: (i) a series breathholds which feedback provided enable reproducible breathholding; (ii) no feedback; (iii)...
Abstract Background This study evaluated the vascular changes in macular and peripapillary regions before after silicone oil (SO) removal patients with rhegmatogenous retinal detachment. Methods single-center case series assessed who underwent SO at one hospital. Patients pars plana vitrectomy perfluoropropane gas tamponade (PPV + C 3 F 8 ) were selected as controls. Superficial vessel density (SVD) superficial perfusion (SPD) by optical coherence tomography angiography (OCTA)....
ABSTRACT Aims: The goal of this study is to create and verify a nomogram estimate operating time in rectal cancer (RC) patients based on clinicopathological factors MRI/CT measurements before surgery. Materials Methods: was developed cohort who underwent laparoscopic anterior resection (L-AR) for RC. pelvis parameters were collected. Risk long determined by univariate multivariate logistic regression analyses, established with independent risk factors. performance the evaluated. An...
Trophoblast cell-surface antigen 2 (Trop-2) is a tumor-associated that connected with the development of various tumors and has been identified as promising target for tumor immunotherapy. To date, immunotherapy against Trop-2 mainly relies on specific targeting by monoclonal antibody in antibody-drug conjugate (ADC). Alternatively, single domain antibodies nanobodies (Nbs) possesses unique properties such smaller size, better tissue penetration, etc., to make them good candidates targeting....
Abstract Thick slab two‐dimensional phase contrast (2D PC) angiography provides a large amount of anatomical information in short acquisition time. Quantitative velocity is, however, destroyed by the necessary projection dephasing gradient. We present 2D PC scheme which retains quantitative thick acquisition. A produces an image is through entire vessel. Accurate measurements must take into account intravoxel cancellation caused distribution velocities within In addition to description data...
Abstract A receive‐only phased‐array coil was designed to image the lower extremities. The array consists of four volume coils placed on two cylindrical formers. has ability both legs simultaneously over a 40 cm longitudinal field view (FOV). Experiments using phantoms show an increase in signal‐to‐noise ratio (SNR) regions interest through center by average factor 2.8 body and 1.5 GE 4‐channel torso array. In vivo data acquired from 10 subjects that X provided similar SNR improvement...
To determine whether electroacupuncture (EA) or moxibustion-like stimulation (MLS) can affect the cutaneous and/or systemic hypothalamic-pituitary-adrenal (HPA) axes.Rats were divided into Control, EA, 37°C MLS and 43.5°C groups. EA performed at bilateral ST36 LI4. The expression of corticotropin-releasing factor (CRF), adrenocorticotropic hormone (ACTH) glucocorticoid receptor (GR) was detected in local tissues site LI4 by immunohistochemical staining. In addition, levels CRF, ACTH...
Chronic inflammatory demyelinating polyradiculoneuropathy is an autoimmune disease characterized by recurrent demyelination and remyelination with resultant thickening of the peripheral nerves. We report a case in which sonography was instrumental demonstrating diffuse nerve hypertrophy. On sonography, both brachial plexuses were found to be diffusely hypertrophic hypoechoic. Similar findings noted for median, sciatic, femoral The plexus confirmed MRI. © 2000 John Wiley & Sons, Inc. J Clin...
This prospective study evaluated the performance of 3D magnetic resonance elastography imaging for predicting microvascular invasion(MVI) T1 staging renal clear cell carcinoma. 80 consecutive patients were enrolled. The mean MRE stiffness value has significant difference between tumor with MVI (5.4±0.6 Kpa) or without (4.1±0.3 (p<0.05). sensitivity, specificity, positive predictive value, negative AUC to predict 100%, 75%, 63%, 96%, 0.87, respectively. promising...
Objective To observe the refractive changes and visual function recovery of patients after various types vitrectomy,and provide basis for late optical correction.Methods It was a retrospective case-control study.Two hundred fifty postvitrectomy patients,including 147 males 103 females,were followed up from January 2009 to February 2011.The ranged in age 3 78 years (mean 48.6±16.4 years).They were divided into groups based on type surgical technique: including simple vitrectomy,87 patients;...