A5100606565- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
- Animal Virus Infections Studies
- Thermal Regulation in Medicine
- Virus-based gene therapy research
- Plant and Fungal Interactions Research
- Immunodeficiency and Autoimmune Disorders
- Aerodynamics and Acoustics in Jet Flows
- Acoustic Wave Phenomena Research
- CAR-T cell therapy research
- Retinal Diseases and Treatments
- Gut microbiota and health
- Human Motion and Animation
- Plant Virus Research Studies
- Microbial infections and disease research
- Viral gastroenteritis research and epidemiology
- Remote Sensing in Agriculture
- Retinal Imaging and Analysis
- Immune responses and vaccinations
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- vaccines and immunoinformatics approaches
- Eosinophilic Disorders and Syndromes
- Smart Agriculture and AI
- Clostridium difficile and Clostridium perfringens research
- Bacteriophages and microbial interactions
Heilongjiang Bayi Agricultural University
2023-2024
Xuzhou Medical College
2023-2024
Yangzhou University
2016-2022
Ministry of Agriculture and Rural Affairs
2022
Renji Hospital
2020
Shanghai Jiao Tong University
2020
Shanghai Normal University
2007
Academy of Military Medical Sciences
2006
Variants of coronavirus porcine epidemic diarrhea virus (PEDV) frequently emerge, causing an incomplete match between the vaccine and variant strains, which affects efficacy. Designing vaccines with rapidly replaceable antigens high efficacy is a promising strategy for prevention infection PEDV strains. In our study, three different types self-assembled nanoparticles (nps) targeting receptor-binding N-terminal domain (NTD) C-terminal (CTD) S1 protein, named NTDnps, CTDnps, NTD/CTDnps, were...
Bovine tuberculosis (bTB) caused by Mycobacterium bovis is an important zoonotic disease. This infection difficult to control because of the limited ability tuberculin skin test (TST) and ancillary IFN-γ release assay detect all infected animals. In this study, we aimed develop efficient based on enzyme-linked immunospot (ELISpot) technique for diagnosis bTB, with monoclonal antibodies 3E9 Bio-labeled 6F8 used as capture detection antibodies, respectively. As expected, there were...
ABSTRACT Limited information on the virome and bacterial community hampers our ability to discern systemic ecological risk factors that cause cattle diarrhea, which has become a pressing issue in control of disease. A total 110 viruses, 1,011 genera, 322 complete viral genomes were identified from 70 sequencing samples mixed with 1,120 fecal 58 farms northeast China. For diarrheic samples, varied terms composition, abundance, diversity, geographic distribution relation different...
An airfoil with a porous trailing edge has low noise emission; thus, using medium is good technique for further reduction of wind turbine noise. In this paper, to reduce while minimizing the negative influence on aerodynamic performance, new filling method proposed such that only used in suction side half edge, which more sensitive generation. The large eddy simulation (LES) flow and Ffowcs Williams Hawkings (FW-H) acoustics are used. At Reynolds number 2.63 × 105 various angles attack, an...
To investigate the correlation of clinical characteristics, fever serum biomarkers with cytokine release syndrome (CRS) in patients relapsed/refractory multiple myeloma (R/R MM) treated chimeric antigen receptor T cell (CAR-T) immunotherapy.
Objective To express the murine Flt3 ligand (FL) protein in a prokaryotic expression system and to evaluate its application vitro preparation of different dendritic cell (DC) subsets. Methods A fragment flt3l gene was amplified by PCR then used construct recombinant plasmid pCold-flt3l. The transformed E. coli BL21(DE3) carrying were induced IPTG FL protein. expressed fusion purified using His bind purification kit. SDS-PAGE Western blot assay performed for further analysis. Bone...
To investigate the safety and efficacy of novel CD19-KIRS2/Dap12-BB chimeric antigen receptor T cells (CAR-T cells) in treatment relapsed/refractory B-cell malignancy (R/R BCM).Three patients with R/R BCM treated CAR-T from June 2020 to November were enrolled, including 1 case acute lymphoblastic leukaemia (B-ALL) 2 cases non-Hodgkin's lymphoma (NHL), adverse reactions observed.After infusion, patient B-ALL achieved complete remission (CR) minimal residual disease (MRD) turned negative, NHL...