A5050390575- COVID-19 Clinical Research Studies
- Radiomics and Machine Learning in Medical Imaging
- Palliative Care and End-of-Life Issues
- COVID-19 diagnosis using AI
- Immune Cell Function and Interaction
- Pain Management and Opioid Use
- Immunotherapy and Immune Responses
- Biosensors and Analytical Detection
- COVID-19 and healthcare impacts
- SARS-CoV-2 detection and testing
- SARS-CoV-2 and COVID-19 Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Respiratory Support and Mechanisms
- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Advanced biosensing and bioanalysis techniques
- T-cell and B-cell Immunology
- Sepsis Diagnosis and Treatment
- Cancer survivorship and care
- Long-Term Effects of COVID-19
- Thermal Regulation in Medicine
- Pediatric health and respiratory diseases
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Asthma and respiratory diseases
- Advanced X-ray and CT Imaging
Hubei Cancer Hospital
2017-2024
Shanghai Medical College of Fudan University
2024
Fudan University Shanghai Cancer Center
2019-2024
Dalian Medical University
2016-2024
Chongqing Medical University
2016-2024
Second Affiliated Hospital of Chongqing Medical University
2016-2024
Chung-Ang University
2021-2024
Stony Brook University
2024
Second Affiliated Hospital of Zhejiang University
2024
Hubei University
2024
Background: The coronavirus disease 2019 (COVID-19) has become a global challenge since the December 2019. hospital stay is one of prognostic indicators, and its predicting model based on CT radiomics features important for assessing patients' clinical outcome. study aimed to develop test machine learning-based models in patients with COVID-19 pneumonia. Methods: This retrospective, multicenter enrolled laboratory-confirmed SARS-CoV-2 infection their initial images from 5 designated...
Abstract Background Interleukin-6 (IL-6) was proposed to be associated with the severity of coronavirus disease 2019 (COVID-19). The present study aimed explore kinetics IL-6 levels, validate this association in COVID-19 patients, and report preliminary data on efficacy receptor blockade. Methods We conducted a retrospective single-institutional 901 consecutive confirmed cases. Serum concentrations were tested admission and/or during hospital stay. Tocilizumab given 16 patients elevated...
Abstract Objectives To develop and test machine learning-based CT radiomics models for predicting hospital stay in patients with pneumonia associated SARS-CoV-2 infection. Design Cross-sectional Setting Multicenter Participants A total of 52 laboratory-confirmed infection their initial images were enrolled from 5 designated hospitals Ankang, Lishui, Zhenjiang, Lanzhou, Linxia between January 23, 2020 February 8, 2020. As 20, remained or non-findings excluded. Therefore, 31 72 lesion segments...
Rationale: Chest computed tomography (CT) has been used for the coronavirus disease 2019 (COVID-19) monitoring. However, imaging risk factors poor clinical outcomes remain unclear. In this study, we aimed to assess characteristics and associated with adverse composite endpoints in patients COVID-19 pneumonia. Methods: This retrospective cohort study enrolled laboratory-confirmed from 24 designated hospitals Jiangsu province, China, between 10 January 18 February 2020. Clinical initial CT...
Abstract Background In January 19, 2020, first case of 2019 novel coronavirus (2019-nCoV) pneumonia (COVID-19) was confirmed in Chongqing municipality, China. Methods this retrospective, descriptive, multiple-center study, total 267 patients with COVID-19 by real-time RT-PCR from Jan 19 to Feb 16, 2020 were recruited. Epidemiological, demographic, clinical, radiological characteristics, laboratory examinations, and treatment regimens collected on admission. Clinical outcomes followed up...
One of the main aims research on nonmedical opioid use (NMOU) is to reduce frequency NMOU behaviors through interventions such as universal screening, reduced exposure, and more intense follow-up patients with elevated risk. The absence data behavior major barrier conducting NMOU.To determine overall independent predictors for behavior.In this prognostic study, 3615 cancer were referred supportive care center at MD Anderson Cancer Center from March 18, 2016, June 6, 2018. Patients eligible...
Anion exchange membrane (AEM) water electrolyser provides a promising alternative to proton electrolysis due the relative cheap of AEM and no-need expensive platinum group catalysts. However, development is hampered by low alkaline dimensional stability AEMs, especially in highly concentrated solution at elevated temperatures. Recently we synthesized poly(triphenyl N-methylquinuclidinium) with excellent stability. To further improve mechanical strength this kind AEM, work, added...
Mechanical ventilation (MV) is the main supportive treatment of acute respiratory distress syndrome (ARDS), but it may lead to ventilator-induced lung injury (VILI). Large epidemiological studies have found that obesity was associated with lower mortality in mechanically ventilated patients injury, which known as “obesity paradox.” However, effects on VILI are unknown. In present study, wild-type mice were fed a high-fat diet (HFD) and high tidal volume investigate vivo, pulmonary...
To determine the patterns of chest computed tomography (CT) evolution according to disease severity in a large coronavirus 2019 (COVID-19) cohort Jiangsu Province, China.This retrospective study was conducted from January 10, 2020, February 18, 2020. All patients diagnosed with COVID-19 Province were included, retrospectively. Quantitative CT measurements pulmonary opacities including volume, density, and location extracted by deep learning algorithm. Dynamic these investigated symptom onset...
This paper is responding to the MIA-COV19 challenge classify COVID from non-COVID based on CT lung images. The COVID-19 virus has devastated world in last eighteen months by infecting more than 182 million people and causing over 3.9 deaths. overarching aim predict diagnosis of chest radiographs, through development explainable vision transformer deep learning techniques, leading population screening a rapid, accurate transparent way. In this competition, there are 5381 three-dimensional...
Abstract Background Inflammation and endothelial barrier dysfunction are the major pathophysiological changes in acute respiratory distress syndrome (ARDS). Sphingosine-1-phosphate receptor 3 (S1PR3), a G protein-coupled receptor, has been found to mediate inflammation cell (EC) integrity. However, function of S1PR3 ARDS not fully elucidated. Methods We used murine lipopolysaccharide (LPS)-induced model an LPS- stimulated ECs investigate role anti-inflammatory effects protection during ARDS....
Journal of Palliative MedicineVol. 23, No. 7 Letters to the EditorA Survey on Physical and Mental Distress among Cancer Patients during COVID-19 Epidemic in Wuhan, ChinaYu Qian, Kun Wu, Hongbin Xu, Dan Bao, Fengming Ran, Wei Wei, Tiancui Cheng, Dingfeng Huang, Xi Lin, Eduardo Bruera, Desheng Hu, Yuan WuYu QianDepartment Medical Oncology Tongji College, Huazhong University Science Technology, Hubei Hospital, Hubei, China.*Co-first authors.Search for more papers by this author, WuDepartment...
Patients with HCC receiving TACE have various clinical outcomes. Several prognostic models been proposed to predict outcomes for patients hepatocellular carcinomas (HCC) undergoing transarterial chemoembolization (TACE), but establishing an accurate model remains necessary. We aimed develop a radiomics signature from pretreatment CT establish combined radiomics-clinic (CRC) survival these patients. compared this CRC the existing in predicting patient survival. This retrospective study...
We report the development of a reproducible and highly sensitive surface-enhanced Raman scattering (SERS) substrate using butanol-induced self-assembly gold nanoparticles (AuNPs) its application as rapid diagnostic platform for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The process was used to generate uniform assembly AuNPs, with multiple hotspots, achieve high reproducibility. When an aqueous droplet containing AuNPs target DNAs dropped onto butanol droplet, dehydration...
Cytokine memory for IFN ‐γ production by effector/memory T h1 cells plays a key role in both protective and pathological immune responses. To understand the epigenetic mechanism determining ontogeny of characterized stable effector functions, we identified ‐cell‐specific methylation pattern at IFNG promoter CNS ‐1 ex vivo cells, investigated dynamics these regions during development cells. During differentiation, demethylation occurred as early 16 h, this process was independent cell...