Hongbin Xu

ORCID: 0000-0003-2665-2720
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About
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Research Areas
  • Intraperitoneal and Appendiceal Malignancies
  • Appendicitis Diagnosis and Management
  • Ovarian cancer diagnosis and treatment
  • Pharmacological Effects of Medicinal Plants
  • Drug Transport and Resistance Mechanisms
  • Tuberculosis Research and Epidemiology
  • Hernia repair and management
  • Inflammatory Biomarkers in Disease Prognosis
  • Omental and Epiploic Conditions
  • Adrenal and Paraganglionic Tumors
  • Healthcare professionals’ stress and burnout
  • Mycobacterium research and diagnosis
  • Trace Elements in Health
  • Inflammatory mediators and NSAID effects
  • Liver Disease and Transplantation
  • Health and Wellbeing Research
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Cancer Mechanisms and Therapy
  • Infectious Diseases and Tuberculosis
  • Obesity, Physical Activity, Diet
  • Neurological Disease Mechanisms and Treatments
  • Organ Transplantation Techniques and Outcomes
  • Pharmacological Effects of Natural Compounds
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Liver Disease Diagnosis and Treatment

Aerospace Center Hospital
2017-2025

Huazhong University of Science and Technology
2011-2024

Zhengzhou University
2024

Ningbo University
2023-2024

Ningbo First Hospital
2022-2024

Hainan Medical University
2020-2023

Nanchang Center for Disease Control and Prevention
2020-2023

Nanjing University of Chinese Medicine
2020-2023

Beijing Shijitan Hospital
2020-2021

Capital Medical University
2020-2021

Abstract Stringent COVID-19 control measures were imposed in Wuhan between January 23 and April 8, 2020. Estimates of the prevalence infection following release restrictions could inform post-lockdown pandemic management. Here, we describe a city-wide SARS-CoV-2 nucleic acid screening programme May 14 June 1, 2020 Wuhan. All city residents aged six years or older eligible 9,899,828 (92.9%) participated. No new symptomatic cases 300 asymptomatic (detection rate 0.303/10,000, 95% CI...

10.1038/s41467-020-19802-w article EN cc-by Nature Communications 2020-11-20

High occupational burnout among general practitioners (GPs) is an important challenge to China's efforts strengthen its primary healthcare delivery; however, data help understand this issue are unavailable. This study aimed investigate the prevalence of and associated factors GPs.A cross-sectional design was used collect from December 12, 2014, March 10, 2015, with a self-administered structured questionnaire 1015 GPs (response rate, 85.6%) in Hubei Province, Central China. Burnout measured...

10.1186/s12889-019-7755-4 article EN cc-by BMC Public Health 2019-12-02

10.1111/j.1469-0691.2011.03716.x article EN publisher-specific-oa Clinical Microbiology and Infection 2011-11-07

Abstract Background P21 (WAF1/Cip1) binds to cyclin-dependent kinase complexes and inhibits their activities. It was originally described as an inhibitor of cancer cell proliferation. However, many recent studies have shown that p21 promotes tumor progression when accumulated in the cytoplasm. So far, little is known about correlation between cytoplasmic drug resistance. This study aimed investigate role cisplatin resistance ovarian cancer. Methods RT-PCR, western blot immunofluorescence...

10.1186/1471-2407-11-399 article EN cc-by BMC Cancer 2011-09-21

Journal of Palliative MedicineVol. 23, No. 7 Letters to the EditorA Survey on Physical and Mental Distress among Cancer Patients during COVID-19 Epidemic in Wuhan, ChinaYu Qian, Kun Wu, Hongbin Xu, Dan Bao, Fengming Ran, Wei Wei, Tiancui Cheng, Dingfeng Huang, Xi Lin, Eduardo Bruera, Desheng Hu, Yuan WuYu QianDepartment Medical Oncology Tongji College, Huazhong University Science Technology, Hubei Hospital, Hubei, China.*Co-first authors.Search for more papers by this author, WuDepartment...

10.1089/jpm.2020.0240 article EN Journal of Palliative Medicine 2020-05-15

Abstract Chromium compounds are important basic chemicals essential to many industries. In the traditional process for manufacturing these compounds, utilization efficiency of resources and energy is quite low. Large amounts chromium‐containing toxic solid wastes exhaust gas discharged, resulting in serious pollution problems. A green chromium has been developed by Institute Process Engineering, Chinese Academy Sciences Beijing, China. With design objective eliminating at source, this...

10.1002/ep.10033 article EN Environmental Progress 2004-11-19

<b><i>Background:</i></b> Multidrug resistance (MDR) presents a problem in cancer chemotherapy, and developing new agents to overcome MDR is important. This study intends investigate the reversal effect of β-elemene on human breast carcinoma MCF-7 doxorubicin-resistant cells. <b><i>Methods:</i></b> MTT cytotoxicity assays, flow cytometry, Western blot analysis were performed antiproliferative effects combination anticancer drugs with β-elemene,...

10.1159/000337178 article EN Pharmacology 2012-01-01

Abstract Background Mesenchymal stem cells (MSCs) have been considered to be the attractive vehicles for delivering therapeutic agents toward various tumor diseases. This study was explore distribution pattern, kinetic delivery of adenovirus, and efficacy MSC loading E1A mutant conditionally replicative adenovirus Adv-Stat3(-) which selectively replicated expressed high levels anti-sense Stat3 complementary DNA in breast cancer melanoma cells. Methods We assessed release ability (CRAd) from...

10.1186/1476-4598-10-134 article EN cc-by Molecular Cancer 2011-11-03

Summary Studies on turnover intention among Chinese general practitioners (GPs) at the national level are limited. This study aimed to assess leave and its associated factors a nationally representative sample of GPs. The participants were selected using multistage stratified random sampling method. A self‐administered structured questionnaire was used collect data from 3236 GPs in China between October 2017 February 2018. multiple linear stepwise regression analysis identify with intention....

10.1002/hpm.2921 article EN The International Journal of Health Planning and Management 2019-11-27

Two patients presenting with subcutaneous nodules, plaques, papules and ulceration caused by Trichophyton rubrum are described in this report. The first case was a 46-year-old woman referred erythema desquamation over her trunk, hands feet for 30 years, progressing to nodules arms scalp the last 2 years. second 34-year-old man who presented 2-year-history of itchy, papules, cyst around his ear, on neck 1 year. diagnoses were suspected after direct microscopical examinations discharge...

10.1111/j.1439-0507.2006.01324.x article EN Mycoses 2006-11-28
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