Fuquan Liu

ORCID: 0000-0001-6192-5419
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About
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Research Areas
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Liver Disease Diagnosis and Treatment
  • Liver Disease and Transplantation
  • Advanced X-ray and CT Imaging
  • MRI in cancer diagnosis
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Liver physiology and pathology
  • Radiomics and Machine Learning in Medical Imaging
  • Immune Cell Function and Interaction
  • Cancer Immunotherapy and Biomarkers
  • Polyomavirus and related diseases
  • Remote-Sensing Image Classification
  • 3D Modeling in Geospatial Applications
  • Liver Diseases and Immunity
  • Phagocytosis and Immune Regulation
  • Geographic Information Systems Studies
  • Obsessive-Compulsive Spectrum Disorders
  • Organ Transplantation Techniques and Outcomes
  • Power Systems and Renewable Energy
  • Remote Sensing and Land Use
  • International Science and Diplomacy
  • Ovarian function and disorders
  • Uterine Myomas and Treatments
  • Reproductive tract infections research
  • Science, Research, and Medicine

Capital Medical University
2014-2025

Beijing Shijitan Hospital
2007-2025

Peking University
2020-2023

Beijing Jishuitan Hospital
2023

Beijing University of Chinese Medicine
2022

Capital University
2021

Inner Mongolia University of Technology
2020

Yuhuangding Hospital
2018

Creative Research Enterprises (United States)
2018

Qingdao University
2018

Wedged hepatic venous pressure (WHVP) is a crucial variable for accurately assessing the gradient (HVPG) and vital diagnosis prognostic evaluation of patients with portal hypertension (PH). To investigate anatomical characteristics balloon-occluded angiography in PH analyze relationship between WHVP (PVP). This retrospective study included 877 who met inclusion criteria from January 2020 to June 2024. Routine innovative was performed during transjugular intrahepatic portosystemic shunt...

10.3748/wjg.v31.i9.103068 article EN World Journal of Gastroenterology 2025-02-18

Invariant NKT cells (iNKT) are CD1d-restricted T with the capacity of antitumor immunity. The safety autologous iNKT cell treatment in hepatocellular carcinoma (HCC) has been verified. This study aimed to investigate its efficacy advanced HCC after transarterial chemoembolization (TACE) failure.This open-label, randomized, controlled, trial enrolled 60 patients unresectable TACE failure at three centers. Transarterial embolization (TAE) was used instead protect function. Patients were...

10.2147/jhc.s416933 article EN cc-by-nc Journal of Hepatocellular Carcinoma 2023-08-01

Nod-like receptor (NLR) family pyrin domain containing 3 (NLRP3) has been regarded as an important initiator or promoter in multiple inflammatory diseases. However, the relationship between cannabinoid 1 (CB1) and macrophage NLRP3 inflammasome corresponding molecular mechanism liver inflammation remain unclear. Mouse injury models were induced by carbon tetrachloride (CCl4) methionine-choline-deficient high fat (MCDHF) diet. Human tissues obtained from patients with different chronic CB1...

10.1016/j.omtn.2020.04.010 article EN cc-by-nc-nd Molecular Therapy — Nucleic Acids 2020-04-28

Early treatment of potato diseases can increase the yield in later stage, so correct diseased areas identification leaves is great significance. Deep learning effectively obtain invariant features and avoid limitations artificial feature extraction, it gradually applied to hyperspectral image classification. Aiming at local disease spots with different diseases, this paper used 1D-CNN adaptively extract features, as realize diseases. In order verify accuracy algorithm, labels calibration...

10.1109/icaica50127.2020.9182577 article EN 2022 IEEE International Conference on Artificial Intelligence and Computer Applications (ICAICA) 2020-06-01

To evaluate the efficacy of main portal vein stents combined with iodine-125 (125I) to treat tumor thrombus.From January 1, 2010 2015, 111 patients were diagnosed liver cancer thrombus. They non-randomly assigned undergo treatment transarterial chemoembolization (TACE)/transarterial embolization (TAE) + 125I implantation (Group A) and TACE/TAE only B). After operation, scheduled follow-up was performed at 6, 12 24 mo. The recorded information included clinical manifestations, survival rate,...

10.4251/wjgo.v10.i12.496 article EN cc-by-nc World Journal of Gastrointestinal Oncology 2018-12-14

Management of elderly patients with hepatocellular carcinoma (HCC) has become a major concern. Some data suggest that cryoablation improves the outcomes HCC, but its efficacy and safety remain unknown. This study aimed to evaluate compare percutaneous those radiofrequency ablation (RFA) for HCC patients.In all, 223 small aged ≥70 years, treatment-naïve, without metastasis were enrolled randomized into group (n = 112) or RFA 111) from July 2015 October 2018. The primary endpoint was local...

10.1111/liv.15169 article EN Liver International 2022-01-22

Abstract Objective To investigate the prognostic value of baseline magnetic resonance imaging (MRI) texture analysis hepatocellular carcinoma (HCC) treated with transcatheter arterial chemoembolization (TACE) and microwave ablation (MWA). Methods MRI was performed on 102 patients HCC before receiving TACE combined MWA in this retrospective study. The best 10 features were screened as a feature group for each sequence by MaZda software using mutual information coefficient (MI), nonlinear...

10.1007/s00261-020-02891-y article EN cc-by Abdominal Radiology 2021-01-01

IQ motif-containing guanosine triphosphatase (GTPase)-activating protein 1 (IQGAP1) is a cytosolic scaffolding involved in cell migration. Our previous studies suggest sphingosine 1-phosphate (S1P) triggers bone marrow (BM) mesenchymal stromal cells (BMSCs) to damaged liver, thereby promoting liver fibrosis. However, the role of IQGAP1 S1P-induced BMSC migration and fibrogenesis remains unclear. Chimeric mice BM labeled by EGFP were used build methionine-choline-deficient high-fat...

10.1016/j.omtn.2021.12.020 article EN cc-by-nc-nd Molecular Therapy — Nucleic Acids 2021-12-17

Background: Transarterial chemoembolization (TACE) is widely used for patients with unresectable hepatocellular carcinoma (HCC); however, previous studies have demonstrated that conventional TACE (cTACE) might affect hepatic hemodynamics, which both associate liver cirrhosis and survival.Drugeluting bead (DEB-TACE) improves treatment efficacy safety, but its effects on the hemodynamics of HCC remain unknown.Methods: This retrospective cohort study included treated DEB-TACE from April 2018 to...

10.21037/jgo-23-76 article EN Journal of Gastrointestinal Oncology 2023-02-01

Objective Schizophrenia is a debilitating mental disorder with high disability rate that characterized by negative symptoms such as apathy, hyperactivity, and anhedonia can make daily life challenging impair social functioning. In this study, we aim to investigate the effectiveness of homestyle rehabilitation in mitigating these associated factors. Methods A randomized controlled trial was conducted compare efficacy hospital for 100 individuals diagnosed schizophrenia. The participants were...

10.3389/fpsyt.2023.1138794 article EN cc-by Frontiers in Psychiatry 2023-04-17

This article analyses the pre-management methods and measures for youth science fund projects granted by National Natural Science Foundation of China.Systematic procedures include mobilization,preliminary research preparation,professional training counseling,modifying application,form content examination,which can improve efficiency China project management. Key words: National China;  Youth project;  Pre-management

10.3760/cma.j.issn.1006-1924.2014.02.016 article EN Zhonghua yixue keyan guanli zazhi 2014-04-21

Transarterial chemoembolization (TACE) is an effective treatment for primary hepatocellular carcinoma (PHC). Radioactive iodine therapy has been used in the of advanced PHC, especially patients with portal vein tumor thrombosis. However, data on therapeutic effect TACE combined radioactive PHC are scarce.To investigate clinical efficacy implantation via perfusion computed tomography (CT).For this study, 98 were recruited and divided randomly into study control groups. Patients group treated...

10.4240/wjgs.v15.i1.105 article EN World Journal of Gastrointestinal Surgery 2023-01-17

<h3>Background</h3> Hepatocellular carcinoma remains a leading cause of mortality worldwide, accounting for over three quarter million deaths annually.<sup>1</sup> While transarterial chemoembolization (TACE) therapy is the current first-line intervention roughly 70–80% cases which are non-resectable,<sup>2–6</sup> repeated treatments quickly lead to recalcitrance in recurring tumors, and 5-year survival rates linger at an abysmal 18%.<sup>7</sup> The results our phase 1 trial indicated that...

10.1136/jitc-2023-sitc2023.0593 article EN cc-by-nc Regular and Young Investigator Award Abstracts 2023-10-31

Objective: To investigate self-stigma’s influence on schizophrenia patients’ quality of life and its mediated impact by various factors. Methods: This study adopted a cross-sectional design randomly selected 170 hospitalized patients with for evaluation. The assessment tools included the Positive Negative Syndrome Scale (PANSS), Self-Esteem Inventory (SEI), Connor-Davidson Resilience (CD-RISC), Internalized Stigma Mental Illness (ISMI), Schizophrenia Quality Life (SQLS), Coping Questionnaire...

10.22541/au.170019936.66965830/v1 preprint EN Authorea (Authorea) 2023-11-17
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