Lu Shi

ORCID: 0000-0002-2114-6389
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About
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Research Areas
  • Plant Stress Responses and Tolerance
  • Plant-Microbe Interactions and Immunity
  • High Altitude and Hypoxia
  • Plant Pathogens and Fungal Diseases
  • Plant Molecular Biology Research
  • Cancer, Hypoxia, and Metabolism
  • Fibroblast Growth Factor Research
  • Phytochemistry and Biological Activities
  • Plant responses to water stress
  • Phytochemicals and Antioxidant Activities
  • Cancer-related molecular mechanisms research
  • Environmental Changes in China
  • Genomics, phytochemicals, and oxidative stress
  • Rice Cultivation and Yield Improvement
  • Remote-Sensing Image Classification
  • Environmental and Agricultural Sciences
  • Thermal Regulation in Medicine
  • Kruppel-like factors research
  • Genetics, Aging, and Longevity in Model Organisms
  • RNA Research and Splicing
  • Advanced Image Fusion Techniques
  • Plant Gene Expression Analysis
  • Cardiac Ischemia and Reperfusion
  • Genomics and Phylogenetic Studies
  • Polyamine Metabolism and Applications

Wenzhou Medical University
2009-2025

First Affiliated Hospital of Wenzhou Medical University
2016-2025

Yibin University
2017-2024

Nanjing Agricultural University
2012-2023

Jiangsu Academy of Agricultural Sciences
2023

Chinese Academy of Sciences
2017-2022

Zhejiang University
2022

Aerospace Information Research Institute
2022

Institute of Zoology
2017-2020

State Key Laboratory of Membrane Biology
2018-2019

In eukaryotes, mechanisms such as alternative splicing (AS) and translation initiation (ATI) contribute to organismal protein diversity. Specifically, factors play crucial roles in responses environment development cues; however, the underlying are not well investigated plants. Here, we report parallel employment of short-read RNA sequencing, single molecule long-read sequencing proteomic identification unravel AS isoforms previously unannotated proteins response abscisic acid (ABA)...

10.1111/tpj.13571 article EN The Plant Journal 2017-04-13

Proanthocyanidins (PAs) are the main products of flavonoid biosynthetic pathway in seeds, but their biological function during seed germination is still unclear. We observed that delayed with increase exogenous PA concentration Arabidopsis. A similar inhibitory effect occurred peeled Brassica napus which was by measuring radicle elongation. Using abscisic acid (ABA), a and metabolic inhibitor, gene expression analysis real-time polymerase chain reaction, we found PAs on due to promotion ABA...

10.1111/j.1744-7909.2012.01142.x article EN Journal of Integrative Plant Biology 2012-07-06

Abstract Paenibacillus polymyxa (P. ) NSY50, isolated from vinegar residue substrate, suppresses the growth of Fusarium oxysporum in cucumber rhizosphere and protects host plant pathogen invasion. The aim present study was to evaluate effects NSY50 application on growth, soil properties composition rhizospheric microbial community after exposure oxysporum. Bacterial fungal communities were investigated by Illumina sequencing 16S rRNA gene internal transcribed spacer (ITS) regions (ITS1...

10.1038/srep41234 article EN cc-by Scientific Reports 2017-02-13

In the current research experiment, a sensitive, precise and rapid bioanalytical approach involving detection of fedratinib concentrations in rat plasma by ultra performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) technique was optimized established, it employed to describe changes after oral treatment with various antifungal drugs (isavuconazole, posaconazole, fluconazole itraconazole). An Acquity UPLC BEH reverse-phase C18 column (2.1 mm × 50 mm, 1.7 μm) used for...

10.3389/fphar.2020.626897 article EN cc-by Frontiers in Pharmacology 2021-02-05

Summary Rice ( Oryza sativa L.) has two ecotypes, upland and lowland rice, that have been observed to show different tolerance levels under flooding stress. In this study, rice cultivars, (Up221, flooding‐intolerant) (Low88, flooding‐tolerant), were initially used study their molecular mechanisms in response germination. We variations the Os CBL 10 promoter sequences these cultivars might contribute divergence tolerance. Further analysis using another eight revealed could be classified as...

10.1111/tpj.13881 article EN The Plant Journal 2018-03-01

To explore biocontrol potential of 39 DAEB isolates (doubly antagonistic towards both Verticillium dahliae Kleb and Fusarium oxysporum) against verticillium wilt cotton to elucidate colonization category characteristics an endophytic bacterium with significant activity.Thirty-nine bacteria strains were tested for their ability control in plants caused by a defoliating pathotype V. 107 under controlled conditions. The trial revealed that bacterium, designated HA02, showed activity 107. After...

10.1111/j.1365-2672.2012.05371.x article EN Journal of Applied Microbiology 2012-06-25

Lowland rice (Nipponbare) and upland (Gaoshan 1) that are comparable under normal moderate drought conditions showed dramatic differences in severe conditions, both naturally occurring long-term simulated rapid water deficits. We focused on their root response found enhanced tolerance of to was mainly due the lower level ABA its roots than those lowland rice. first excluded effect biosynthesis catabolism root-accumulated levels types by monitoring expression four OsNCED genes two OsABA8ox...

10.1093/pcp/pcv022 article EN Plant and Cell Physiology 2015-03-02

Exposure to spaceflight and microgravity causes physiologic psychologic changes including bone loss, cardiovascular dysfunction, immune dysfunction. Anemia hematopoietic disorders are observed in astronauts after spaceflight. Hematopoietic stem progenitor cells (HSPCs), which can self-renew give rise all blood cells, play vital roles hematopoiesis homeostasis; however, the molecular mechanisms responsible for impacts of on proliferation HSPCs remain unclear. We maintained mouse marrow...

10.1096/fj.201802413r article EN The FASEB Journal 2019-02-05

The effects of rose-flower extract on antioxidant enzymes were studied. activities catalase (CAT) and glutathione peroxidase (GPx) in 9-month-old senescence-accelerated mice (SAM mice) lower than those 6-month-old SAM mice. Therefore, the most appropriate targets for treatment with extract. CAT GPx treated showed a marked increase whole blood liver. At same time, gene-expression level was upregulated liver, while malondialdehyde content liver brain decreased. Male more sensitive female mean...

10.1139/o04-100 article EN Biochemistry and Cell Biology 2005-02-01

Dual-specificity protein phosphatases (DsPTPs) target both tyrosine and serine/threonine residues play roles in plant growth development. We have characterized an Arabidopsis mutant, dsptp1, which shows a higher seed germination rate better root elongation under osmotic stress than the wild type. By contrast, its overexpression line, DsPTP1-OE, inhibited elongation; complemented DsPTP1-Com, resembles type rescues DsPTP1-OE stress. Expression of AtDsPTP1 is enhanced by coats, bases rosette...

10.1093/jxb/eru484 article EN cc-by Journal of Experimental Botany 2014-12-24

Plant-growth-promoting rhizobacteria (PGPR) can both improve plant growth and enhance resistance against a variety of environmental stresses. To investigate the mechanisms that PGPR use to protect plants under pathogenic attack, transmission electron microscopy analysis proteomic approach were designed test effects new potential strain Paenibacillus polymyxa NSY50 on cucumber seedling roots after they inoculated with destructive phytopathogen Fusarium oxysporum f. sp. cucumerinum (FOC)....

10.3389/fpls.2016.01859 article EN cc-by Frontiers in Plant Science 2016-12-14

It has previously been shown that proanthocyanidins (PAs) in the seed coat of Arabidopsis thaliana have ability to scavenge superoxide radicals (O2−). However, physiological processess PA-deficit seeds are not clear. is hypothesized there exist alternative ways PA-deficient cope with oxidative stress. The content hydrogen peroxide (H2O2) and its relevance activities dismutase (SOD), catalase (CAT) peroxidases was investigated both wild-type mutant seeds. A biochemical staining approach used...

10.1093/aob/mct045 article EN Annals of Botany 2013-02-28

Hull-less pumpkins (Cucurbita pepo L.) are naturally occurring novel variants known as oilseed or naked-seeded pumpkins, and characterized by the absence of a normal lignified seed coat. Due to specialized coat structure, these serve good model for studying formation simplify processing pumpkin seeds. However, causal genes this hull-less trait still remain unknown. Here, bulked segregant analysis fine mapping, we found that mutation single gene, NAC SECONDARY WALL THICKENING PROMOTING FACTOR...

10.1093/hr/uhac136 article EN cc-by Horticulture Research 2022-01-01

Cloud detection is of great significance for optical remote sensing images. Most existing cloud approaches often rely on many thresholds among multiple bands with a wide spectrum range, and normally just can be applied to specific satellite data. difficult in some sensor data limited number available spectral bands. To tackle this challenge, we propose method based random forest (RFCD) only the most common RGB NIR The RFCD normalizes different by calculating top-of-atmosphere (TOA)...

10.1080/22797254.2021.2025433 article EN cc-by-nc European Journal of Remote Sensing 2022-01-12
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