A5101762076- Corneal surgery and disorders
- Hemoglobinopathies and Related Disorders
- Ophthalmology and Visual Impairment Studies
- Intraocular Surgery and Lenses
- Advanced biosensing and bioanalysis techniques
- Pharmacological Effects and Toxicity Studies
- Gastric Cancer Management and Outcomes
- Electrochemical sensors and biosensors
- Antifungal resistance and susceptibility
- Advanced Nanomaterials in Catalysis
- Infectious Diseases and Tuberculosis
- Glaucoma and retinal disorders
- Blood groups and transfusion
- Gastrointestinal motility and disorders
- Lymphoma Diagnosis and Treatment
- Fungal Infections and Studies
- Iron Metabolism and Disorders
- Genomics and Rare Diseases
- Gastrointestinal Tumor Research and Treatment
- Dietary Effects on Health
- Acupuncture Treatment Research Studies
- Lung Cancer Diagnosis and Treatment
- Multiple and Secondary Primary Cancers
- Chronic Kidney Disease and Diabetes
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Tongji Hospital
2024-2025
Huazhong University of Science and Technology
2024-2025
Zhuhai People's Hospital
2017-2025
Jinan University
2017-2024
Nantong University
2024
Soochow University
2021-2024
Nanjing Medical University
2016-2023
First Automotive Works (China)
2022
He Eye Hospital
2022
Chinese Academy of Medical Sciences & Peking Union Medical College
2020
The antiexcitotoxic efficacy of melatonin, a putative endogenous hydroxyl radical scavenger, was studied in primary cultures rat cerebellar granule neurons. Excitotoxicity induced 7- to 9-day-old by an exposure glutamate (15 min the absence magnesium) or receptor agonists, kainate (30 min), and N-methyl-d-aspartate (60 magnesium). Thereafter, were returned culture-conditioned medium for 18 h at end which time viability assessed quantitative staining with...
Abstract Immediate adequacy assessment (IADA) during fine‐needle aspiration (FNA) is not universal and the optimal numberof passes has been well determined. The aim of this study was to evaluate nondiagnostic rates (NDR) with without IADA forthyroid aspirates. Subsequent cytological surgical follow‐upwere reviewed for cases. In addition, we evaluated performed in each FNA determine number. Retrospective analysis NDR on 883 thyroid specimens retrievedthrough a Computer SNOMED Search from our...
Tropical Candida spondylitis is an uncommon cause of lower back pain in patients, especially non-tropical areas or patients not at risk immunocompromise. A 65-year-old woman presented with a six-month history poorly managed low pain, now accompanied by numbness and both extremities. Her medical was significant for tertiary hypertension. Inflammatory markers were mildly elevated. MRI fluid sequences revealed lamellar enhancement the L4-5 vertebral bodies, narrowing intervertebral space,...
<title>Abstract</title> Primary gastro-intestinal lymphomas are the most common extra-nodal but there is no widely-accepted survival prognosis model. We interrogated data from 1 023 consecutive newly-diagnosed people with primary lymphoma. The sites were stomach (55%). Diffuse large B-cell lymphoma (DLBCL) was diagnosis (65%) followed by mucosa associated (MALT) (20%). In DLBCL, of those or intestine better compared small (P = 0.03) and multiple < 0.01). People DLBCL receiving R-CHOP...
Aspergillus fumigatus spondylitis is a rare fungal infection, primarily occurring in immunocompromised patients, although cases immunocompetent individuals have also been reported. While commonly associated with pulmonary infections, it can cause spondylitis. Patients typically present back pain, limb numbness, and neurological compression symptoms. Imaging findings often show vertebral destruction, reduced disk height, paraspinal abscesses, potentially accompanied by characteristic...
Abstract Thalidomide induces γ-globin expression in erythroid progenitor cells, but its efficacy on patients with transfusion-dependent β-thalassemia (TDT) remains unclear. In this phase 2, multi-center, randomized, double-blind clinical trial, we aimed to determine the safety and of thalidomide TDT patients. A hundred 14 years or older were randomly assigned receive placebo for 12 weeks, followed by an extension at least 36 weeks. The primary endpoint was change hemoglobin (Hb) level...
Abstract The distinction between metastatic adenocarcinomas of lung (LAC), breast (BAC), and ovary (OAC) in serous effusions can be very difficult since they all present as tight cell clusters. This is particularly challenging when the malignant effusion patient's initial presentation or patient has a history more than one primary. aim this study to evaluate usefulness WT1, monoclonal CEA (mCEA), TTF1, CA125 antibodies differential diagnosis adenocarcinoma from lung, effusions. Forty‐six...
Abstract Background To describe the very early vault changes in first month after Implantable Collamer Lens (ICL) implantation and to evaluate effect of preoperative biometric factors on vault. Methods Eighty-three eyes from eighty-three subjects with complete data who met follow-up requirements were recruited this retrospective study between May 2019 March 2020. We quantitatively assessed postoperative at 2 h, 1 day, week, following implantation. Associations age, ICL size, spherical...
To ascertain the prevalence of carcinoma in esophagi resected for high-grade dysplasia (HGD) using current criteria and to evaluate histologic features that may predict concurrent carcinoma, we studied specimens from 127 esophagectomies performed HGD, or HGD "suspicious" (HGD/S) Barrett mucosa. Corresponding biopsy 69 cases were reviewed reclassified. Based on original diagnoses, was present 15 (17%) 89 28 (74%) 38 HGD/S cases. By reclassification, only 1 (5%) 21 with had resection specimen....
Abstract Objective This study aimed to evaluate the clinical and laboratory outcomes of a group patients with β‐thalassaemia major or intermedia treated thalidomide. Methods Clinical data were obtained by analysing medical records patients. Using self‐control method, levels haemoglobin (Hb), foetal (HbF), white blood cells ( WBC ) platelets detected before after treatment, adverse reactions recorded. Results Data from 9 analysed. The median these increased 5.13 ± 2.15 g/dL treatment 10.38...
Background. Hydrogen (H2) reportedly produces an antioxidative effect by quenching cytotoxic oxygen radicals. We studied the biological effects of water with dissolved H2 on ischemia-induced cardio-renal injury in a rat model chronic kidney disease (CKD).
Objective: To investigate the principles of differential diagnosis pulmonary infiltrates in cancer patients during outbreak novel coronavirus (2019-nCoV) by analyzing one case lymphoma who presented ground-glass opacities (GGO) after courses chemotherapy. Methods: Baseline demographics and clinicopathological data eligible were retrieved from medical records. Information clinical manifestations, history epidemiology, lab tests chest CT scan images visiting February 13 to 28 collected....
Background. Accelerated burst of polymorphonuclear leukocytes (PMNs) may be involved in the primary pathology enhanced oxidative stress patients with chronic kidney disease (CKD); however, precise mechanism remains unknown. Methylglyoxal (MGO), an α-oxoaldehyde reportedly elevated CKD, could induce apoptosis several cell lines, and generates radicals by reaction hydrogen peroxide (H 2 O ). Thus, we tested if a high MGO uraemic milieu play role PMN injury interaction H .
Objective: We evaluated the long-term safety and efficacy of thalidomide in treatment transfusion-dependent β-thalassemia (TDT). Methods: Fifty patients with TDT were treated followed-up for 5 years. Thalidomide at a 50 mg dose was administered once day after dinner. The increased to 150 mg/d 3 d if well tolerated. After 1 year treatment, hemoglobin (Hb) level stabilized its maximum, gradually reduced maintained minimum dose. hematological response, transfusion dependence, haemolytic...
Background: Telomerase plays a role in the immortalization of cells and carcinogenesis. Previous studies have yielded conflicting results on whether human telomerase RNA (hTER) expression differs nevi, atypical nevi melanomas using polymerase chain reaction‐based telomeric repeat amplification protocol or situ hybridization assays. The aim this study was to evaluate reverse transcriptase (hTERT) staining melanocytic lesions paraffin‐embedded tissues. Methods: Paraffin‐embedded sections from...