A5101768994- Cardiovascular Issues in Pregnancy
- Pregnancy and preeclampsia studies
- Pulmonary Hypertension Research and Treatments
- Mesenchymal stem cell research
- Maternal and fetal healthcare
- Psoriasis: Treatment and Pathogenesis
- Cardiac Structural Anomalies and Repair
- Tissue Engineering and Regenerative Medicine
- Mast cells and histamine
- Skin and Cellular Biology Research
- Electrospun Nanofibers in Biomedical Applications
- Congenital Heart Disease Studies
- Nerve injury and regeneration
- Immune cells in cancer
- Lipid metabolism and disorders
- Skin Protection and Aging
- Corneal Surgery and Treatments
- Pharmacological Effects of Natural Compounds
- Spinal Cord Injury Research
- Multiple Sclerosis Research Studies
- Neuroinflammation and Neurodegeneration Mechanisms
- Head and Neck Cancer Studies
- Connective tissue disorders research
- Traditional Chinese Medicine Analysis
- Galectins and Cancer Biology
Jinan University
2025
Shanghai Jiao Tong University
2014-2024
Renji Hospital
2005-2024
State Key Laboratory of Oncogene and Related Genes
2021
Shanghai Cancer Institute
2021
Xi'an Jiaotong University
2020
Central South University
2020
China Rehabilitation Research Center
2007
Peroxisome proliferator-activated receptor γ (PPARγ) has been shown to be a therapeutic target for preeclampsia (PE). Angiopoietin-like protein 4 (ANGPTL4) is multifunctional secretory involved in regulating lipid metabolism and angiogenesis various tissues. However, the expression of PPARγ ANGPTL4 their interaction PE remain elusive. Here we showed that agonist rosiglitazone upregulated secretion dose-dependent manner HTR8/SVneo cells, human umbilical vein endothelial cells (HUVECs)...
Studies focused on pregnant women with congenital heart disease (CHD)-associated pulmonary hypertension (PH) are scarce and limited by small sample sizes single-center design. This study sought to describe the pregnancy outcomes in CHD without PH.
Allergic conjunctivitis (AC) is the most prevalent form of mucosal allergy, and conditioned medium (CM) from mesenchymal stem cells has been reported to attenuate some allergic diseases. However, therapeutic effects CM different tissue (TSC-CM) on diseases have not tested. Here, we studied topical administration human TSC-CM experimental AC (EAC) mice. Only amniotic epithelial cell-CM (AECM) significantly attenuated eye symptoms reduced infiltration immune levels local inflammatory factors...
Abstract Background Psoriasis is a chronic inflammatory skin disease. Tissue stem cells have exhibited therapeutic effect on psoriatic mice. However, the of topical administration secretome derived from tissue psoriasis has not been reported. Methods The human amniotic epithelial (AEC-SC) and umbilical cord mesenchymal (UMSC-SC) was topically administrated back imiquimod-induced psoriasis-like Subsequently, we observed lesions inflammation Next, further analyzed paracrine factors in AEC-SC...
Although human umbilical cord mesenchymal stem cells (hUC-MSCs) have been identified as a new source of MSCs for potential application in regenerative medicine, their full differentiation has not determined. In particular, whether they the capability to differentiate into epithelial endodermal origin such prostate is unknown. Here we report that when hUC-MSCs were combined with rat urogenital sinus stromal (rUGSSs) and transplanted renal capsule vivo, could epithelial-like be verified by...
Mesenchymal stem cells (MSCs) have been extensively used for the treatment of various diseases in preclinical and clinical trials. In vitro propagation is needed to attain enough use. However, cell aging viability reduction caused by long-time culture not thoroughly investigated, especially function mitochondria lysosomes. Therefore, this study was designed detect mitochondrial lysosomal activity, morphological functional changes human umbilical cord MSCs (UMSCs) after culture.First, we...
Objective: To investigate and analyze disease status risk factors of venous thromboembolism (VTE) during pregnancy puerperium in our country. Methods: Clinical datas were collected from 575 patients diagnosed with VTE hospitalized nine medical institutions country January 1, 2015 to November 30, 2019, retrospectively analyzed it's factors. Results: (1) The proportion was 50.6% (291/575) 49.4% (284/575), respectively. Four died, the mortality rate 0.7% (4/575). cause death pulmonary embolism....
In this study, we aim to find out maternal and fetal outcomes in women with PH resulting from different causes try determine the risk factors related adverse outcomes. 684 were included final analysis, who mainly had pulmonary hypertension secondary congenital heart disease (65.4%). Patients idiopathic have highest mortality (35.3%) lowest live birth rate (82.4%). Mortality is similar between moderate severe women(5.3% vs 9.7%, P=0.17), but much lower (78.6% 89.9%, P＜0.01). The overall was...
The purpose of this study was to observe the influence duration time isometric contraction on blood pressure healthy young males. 16 normal males measured before and after 3 sessions push-up exercise. All subjects did hold for 5 seconds (T5), 10 (T10) 15 (T15), respectively. results indicate that only systolic increased irrespective exercise time, no significant difference found in pressures among times. Also change pulse between T5 T10 groups, but there a remarkable both group T15, T15...