- Traumatic Brain Injury and Neurovascular Disturbances
- Intracranial Aneurysms: Treatment and Complications
- Spinal Fractures and Fixation Techniques
- Cancer-related molecular mechanisms research
- Cerebrospinal fluid and hydrocephalus
- Meningioma and schwannoma management
- Medical Imaging and Analysis
- Head and Neck Surgical Oncology
- Spinal Dysraphism and Malformations
- MicroRNA in disease regulation
- Pituitary Gland Disorders and Treatments
- Pelvic and Acetabular Injuries
- Intracerebral and Subarachnoid Hemorrhage Research
- Glioma Diagnosis and Treatment
- TGF-β signaling in diseases
- Pharmacological Effects and Toxicity Studies
- Natural Compounds in Disease Treatment
- Impact of Technology on Adolescents
- Urban Stormwater Management Solutions
- Lipid metabolism and disorders
- Medical Research and Treatments
- Neurofibromatosis and Schwannoma Cases
- Acute Kidney Injury Research
- Kruppel-like factors research
- Emotion and Mood Recognition
Shanxi Medical University
2015-2025
Beijing University of Civil Engineering and Architecture
2024
Shaanxi Provincial People's Hospital
2011-2022
National Yang Ming Chiao Tung University
2019-2020
Shanxi Province Hospital of Traditional Chinese Medicine
2011-2018
The direct effect of macroscopic loads on the microstructure bone tissue in a vibration environment is not yet known. Therefore, this study aims to investigate macro- and micro-biomechanical properties lumbar spine system under dynamic loading such an environment. We analyzed characteristics osteon by establishing micro-scale model spine, using submodel-specific boundary displacement method based St. Venant's principle. Utilizing results from transient analysis entire as conditions,...
Renal-targeted delivery of triptolide by entrapment in pegylated TRX-20-modified liposomes Zhi-xiang Yuan,1,* Lu Jia,2,* Lee Yong Lim,3 Ju-chun Lin,1 Gang Shu,1 Ling Zhao,1 Ye,1 Xiao-xia Liang,1 Hongming Ji,2 Hua-lin Fu1 1Department Pharmacy, College Veterinary Medicine, Sichuan Agricultural University, Chengdu, Sichuan, 2Department Neurosurgery, Shanxi Provincial People' Hospital, Taiyuan, China; 3Pharmacy, Centre for Optimization Medicines, School Allied Health, The University Western...
In recent years, the extensive use of organophosphorus pesticides, especially unreasonable use, has brought great safety risks to environment. Organic phosphorus pollution become a hotspot, and there are large number microorganisms in soil water body that can degrade pesticides. The degradation performance pesticides is applied variety remediation practices. This paper summarizes current situation pesticide residues, species degrading bacteria its separation screening characteristics...
Abstract Glioblastoma (GBM) is one of the most common aggressive cancers central nervous system in adults with a high mortality rate. Bortezomib boronic acid–based potent proteasome inhibitor that has been actively studied for its anti‐tumour effects through inhibition proteasome. The key component ubiquitin‐proteasome pathway critical protein homeostasis, regulation cellular growth, and apoptosis. Overexpression polo‐like kinase 4 (PLK4) commonly reported tumour cells increases their...
Alzheimer’s disease (AD) is the most common neurodegenerative disease, which associated with extracellular deposition of amyloid-β proteins (Aβ). It has been reported that triptolide (TP), an immunosuppressive and anti-inflammatory agent extracted from a Chinese herb Tripterygium wilfordii, shows potential neuroprotective effects pertinent to AD. However, clinical use TP for AD could be hampered due its high toxicity, instability, poor water solubility, nonspecific biodistribution after...
Determining the nerve of origin for vestibular schwannoma (VS), as a method predicting hearing prognosis, has not been systematically considered. The test can be used to investigate function superior (SVN) and inferior (IVN). This study aimed preoperatively distinguish VS patients using test, determine if this correlated with preservation.A total 106 unilateral were enrolled in prospectively. Each patient received caloric vestibular-evoked myogenic potential (VEMP) cochlear (hearing) before...
Subarachnoid hemorrhage (SAH) is a cerebral disease that severely damages the brain and causes cognitive impairment (CI). Therefore, accurate appropriate treatment strategies are urgently needed. The application of nimodipine can not only improve blood circulation in patients with SAH but also repair ischemic neuron injury.To investigate effects lncRNA nuclear paraspeckle assembly transcript 1 (NEAT1)/miR-27a/microtubule-associated protein tau (MAPT) axis on CI after SAH.One hundred twenty...
1Since Internet addiction (IA) was reported in 1996, research on IA assessment has attracted considerable interest. The development of a real-time detector system can help communities, educational institutes, or clinics immediately assess the risk users. However, current questionnaires were designed to ask users self-report their experiences for at least 6 months. Physiological measurements used assist short-term IA, but physiological properties cannot due lack algorithms. Therefore,...
Endovascular coil occlusion is a successful and rapidly evolving strategy used to treat patients who present with intracranial aneurysms. This study aimed compare the safety efficacy of Avenir® AxiumTM passive mechanically detachable systems.A prospective, multicenter, randomized controlled was carried out at ten medical centers from March 2018 December 2019. A series consecutive diagnosed aneurysms were randomly assigned undergo endovascular treatment either or systems. The short-term...
Intracranial aneurysms (IAs) are bulges of blood vessels in the cerebral area. The development and progression IAs associated with proliferation vascular smooth muscle cells (VSMCs) during phenotypic modulation under environmental cues. MicroRNA-29b (miR-29b) has been studied extensively demonstrated to reduce cell various diseases by binding 3'-untranslated region (3'-UTR) a variety target messenger RNAs (mRNAs), thereby inhibiting their translation. present study aimed investigate role...
This study investigated potential markers for predicting nonfunctioning pituitary adenoma (NFPA) invasion and recurrence by high-throughput tissue microarray analyses. We retrospectively studied two groups of patients: 60 nonrecurrent NFPA cases that included noninvasion subtypes 43 recurrent primary NFPA. A total 31 paired patient samples were evaluated (12 patients with one surgery who had undergone operations, both tumors analyzed). Expressions nuclear receptor subfamily 2 group C member...
Background Valproic acid (VPA) has been widely used to prevent epileptic seizures after neurosurgery in China. We have found that the incidence of liver injury (LI) patients using VPA is higher than other patients. Objective The objective this study was investigate risk factors LI neurosurgery. Methods A nested case-control conducted between September 2019 and March 2021. Cases were matched controls by age body mass index (BMI). Conditional logistic regression estimate odds ratios...
This study investigates the biokinetics of LGT proteome, a potential biomarker severe TBI, in serum TBI patients. The proteome presents abundance diversity is closely associated with pathologic condition Serum may be used as promising marker for evaluating severity TBI.
The occurrence and ecological risks of 16 polycyclic aromatic hydrocarbons (PAHs) in different types urban road runoff Beijing during two typical rainfall events were studied. average concentration PAHs particulate was the order Guanyuanqiao Road (ring road, 15,175 ng/L) > Huayuanqiao (primary 4,792 Dongcheng Alley (alley, 4,774 Nansihuan Viaduct (viaduct, 770 ng/L), much higher than dissolved PAHs. total ∑16PAHs decreased with scouring. Rainfall conditions accumulation early period show a...