A5066203275- Medical Device Sterilization and Disinfection
- Gastroesophageal reflux and treatments
- Gastrointestinal disorders and treatments
- Gallbladder and Bile Duct Disorders
- Helicobacter pylori-related gastroenterology studies
- Esophageal and GI Pathology
- Pediatric Hepatobiliary Diseases and Treatments
- Eosinophilic Esophagitis
- Pharmacological Effects and Toxicity Studies
- Pancreatic and Hepatic Oncology Research
- Retinoids in leukemia and cellular processes
- Management of metastatic bone disease
- Multiple Myeloma Research and Treatments
- Diverticular Disease and Complications
- Cancer-related molecular mechanisms research
- Ubiquitin and proteasome pathways
- Diagnosis and treatment of tuberculosis
- Colorectal Cancer Screening and Detection
- Histone Deacetylase Inhibitors Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Glioma Diagnosis and Treatment
- Bone Tumor Diagnosis and Treatments
- Cancer Mechanisms and Therapy
- MicroRNA in disease regulation
- Microtubule and mitosis dynamics
First Affiliated Hospital of Nanchang University
2013-2023
Nanchang University
2013-2023
Shaanxi Provincial People's Hospital
2016-2022
Shanxi Medical University
2016-2022
Shanxi Province Hospital of Traditional Chinese Medicine
2017
Royal Gwent Hospital
2015
Platelet decline is a frequent side effect of valproic acid, medication commonly prescribed to prevent seizures in neurosurgical patients. However, the risk factors for acid-associated platelet remain poorly understood, and it remains unknown whether linezolid or levetiracetam combination with acid associated thrombocytopenia, as both drugs could lead decrease count. This three center, retrospective nested case–control study aimed develop predictive model prediction acid-induced cohort 356...
We evaluate the efficacy of concomitant therapy for Helicobacter pylori infection and associated factors that influence it in China, where has not previously been investigated. In this prospective study, 374 consecutive patients with H. were randomly assigned to 10 day regimens different proton pump inhibitors: esomeprazole (20 mg)/omeprazole mg), amoxicillin (1000 clarithromycin (500 mg) metronidazole (400 mg). All drugs administered twice daily. A [13C]urea breath test was performed at...
Abstract Glioblastoma (GBM) is one of the most common aggressive cancers central nervous system in adults with a high mortality rate. Bortezomib boronic acid–based potent proteasome inhibitor that has been actively studied for its anti‐tumour effects through inhibition proteasome. The key component ubiquitin‐proteasome pathway critical protein homeostasis, regulation cellular growth, and apoptosis. Overexpression polo‐like kinase 4 (PLK4) commonly reported tumour cells increases their...
Studies have indicated that endoscope reprocessing failure might be attributed to internal damage or residual liquid in endoscopes. However, large-sample survey data on the conditions of endoscopic channels after are lacking. This study used a borescope investigate cleanliness and 213 biopsy at endoscopy center First Affiliated Hospital Nanchang University, provided theoretical basis for efficacy maintenance.A was observe analyze inside channel reprocessed endoscopes (in accordance with...
Abstract It remains challenging for endoscopists to manage pancreaticobiliary diseases in patients with ectopic papilla of Vater by endoscopic retrograde cholangiopancreatography (ERCP). The present study sought evaluate the efficacy and safety ERCP this issue. Consecutive who underwent initial due were retrospectively analyzed. One hundred seven included. success rate cannulation was 83.2%. Endoscopic sphincterotomy, papillary balloon dilation, mechanical lithotripsy performed 12 (11.2%),...
Abstract Addressing pancreaticobiliary disorders concomitant with gastroesophageal varices remains challenging. The goal of this study was to evaluate and compare the efficacy safety endoscopic retrograde cholangiopancreatography (ERCP) in cirrhotic noncirrhotic patients varices. We retrospectively analyzed data consecutive who underwent ERCP. Two hundred seventy ERCP procedures were performed on 208 patients. overall technical success rate 98.5%, no difference found between (98.7% vs 97.7%,...
Background Valproic acid (VPA) has been widely used to prevent epileptic seizures after neurosurgery in China. We have found that the incidence of liver injury (LI) patients using VPA is higher than other patients. Objective The objective this study was investigate risk factors LI neurosurgery. Methods A nested case-control conducted between September 2019 and March 2021. Cases were matched controls by age body mass index (BMI). Conditional logistic regression estimate odds ratios...
In cases of ascites unknown etiology, tuberculosis peritonitis (TBP) is a possible cause but diagnostic challenge. This retrospective case series assessed the effectiveness and safety natural orifice translumenal endoscopic surgery (NOTES(®); American Society for Gastrointestinal Endoscopy [Oak Brook, IL] Endoscopic Surgeons [Los Angeles, CA]) in 7 consecutive patients with suspected TBP.Between September 2011 August 2012, peritoneal biopsy was performed using transgastric NOTES subsequent...
<h3>Introduction</h3> Laparoscopic Nissen’s fundoplication (LNF) is the procedure of choice in surgical management refractory gastroesophageal reflux disease (GORD). Few studies have reported subjective symptomatic outcome and objective investigative postoperatively. The correlation between these two measurements unclear. this study to evaluate a hundred consecutive LNFs relation patient’s anatomic physiologic status after procedure, functional outcome, rate pattern failures. <h3>Method</h3>...
Objective To discuss the application effects of trinitarian visualization teaching model in endoscopy reprocessing practice. Methods Subjects study were divided into group (n=40) and traditional (n=43) by random number table method; Compliance credibility rating endoscope procedures compared between 2 groups. weeks after training, objectives examined assessed questionnaires separately. Results Compliance was higher than (χ2=10.501, P=0.033). The had a compliance, with 47.47...
Objective The study aimed to observe the influence of Puritybile capsules combined with different doses Compound polyethylene glycol (PEG) in bowel preparation. Methods 120 patients were set into three groups (group A, B and C) randomly (40 each). Group A take routine treatment orally. On basis same treat-ment, group added regular dose capsules. C took half The cleaning effect adverse reaction compared among groups. Results According Ottawa Scale, effects as well existing air...
Objective To investigate the operation process, extent of resection, protection function, tumor recurrence and clicical value neuronavigation with intraoperative ultrasound for treating functional glioma; significance correcting brain shift. Methods We analyzed cliclical materical 24 case gliomas which were resected by ultrasound. Results The accuracy localization glioma was 100%. The distance shift 2 to 10mm, an average 4.7mm. After hours MRI confirmed that total removal...
Over the past decade, infections linked to duodenoscopes have become a significant concern, primarily due intricate design of elevator mechanism. Currently, there is limited evidence regarding bacterial contamination level mechanism after clinical use and throughout its various reprocessing stages. This study utilized swab culture technique examine on duodenoscope three stages at Center tertiary hospital. Our findings revealed sever usage, emphasizing that effectiveness manual cleaning...
Objective To investigate the factors related to Department of Neurosurgery, postoperative recurrence WHO grade Ⅱ meningiomas. Methods A total 84 pathologically confirmed cases meningiomas admitted People`s Hospital Shanxi Province between January 2008 and December 2014 were enrolled in this study. The patients followed up for possible studied by using single factor Kaplan-Meier survival analysis multivariate Cox regression analysis. Results The follow-up time ranged from 24 105...
This study aimed to investigate the relationship between gene polymorphisms and clinical factors with concentrations of valproic acid (VPA) in adult patients who underwent neurosurgery China.A total 531 serum concentration samples at steady state were collected from 313 develop a population pharmacokinetic (PPK) model. Data analysis was performed using nonlinear mixed effects modeling. Covariates included demographic parameters, biological characteristics, genetic polymorphism. Bootstrap...