A5102724737- Genomics and Phylogenetic Studies
- Microbial Community Ecology and Physiology
- Bacterial biofilms and quorum sensing
- Bacterial Genetics and Biotechnology
- Microbial Natural Products and Biosynthesis
- Mycorrhizal Fungi and Plant Interactions
- Tea Polyphenols and Effects
- Aquaculture disease management and microbiota
- Soil Carbon and Nitrogen Dynamics
- Fermentation and Sensory Analysis
- Plant Pathogens and Fungal Diseases
- Biological Activity of Diterpenoids and Biflavonoids
- Nerve injury and regeneration
- Plant tissue culture and regeneration
- Probiotics and Fermented Foods
- Phytoestrogen effects and research
- Plant chemical constituents analysis
- Marine Sponges and Natural Products
- Photodynamic Therapy Research Studies
- Skin Protection and Aging
- Environmental and Agricultural Sciences
- Plant-Microbe Interactions and Immunity
- Nerve Injury and Rehabilitation
- Protist diversity and phylogeny
- Bacteriophages and microbial interactions
Ocean University of China
2013-2024
Heilongjiang Academy of Sciences
2024
Hefei University of Technology
2023-2024
Shenzhen University
2022-2023
Fujian Agriculture and Forestry University
2023
Peking University
2009
Northwest A&F University
2009
Marine microorganisms are an important source of new drug leads. However, the discovery and sustainable production these compounds often hampered due to unavailable expression cryptic biosynthetic gene clusters or limited titer. Ribosome engineering response surface methodology (RSM) integrated strategy was developed in this study activate cluster deepsea-derived Streptomyces somaliensis SCSIO ZH66, subsequently isolation, structural analysis, yield enhancement activated compound, anticancer...
Bacillaenes are a class of poly-unsaturated enamines produced by Bacillus strains that notoriously unstable toward light, oxygen, and normal temperature. Herein, in an in-depth study this highly chemotype, the stability biological function bacillaenes were investigated. The structure change bacillaene scaffold was tracked time-course 1H NMR data analysis coupled with differential 2D-NMR spectra method, which demonstrated to be "domino" effect triggered 4′,5′-cis (2 3) configuration...
A filamentous actinomycete strain, designated GW9-2(T), was isolated from a soil sample collected the Fildes Peninsula, King George Island, West Antarctica. The strain identified using polyphasic taxonomic approach. grew slowly on most media tested, producing small amounts of aerial mycelia and no diffusible pigments tested. in presence 0-12 % (w/v) NaCl (optimum, 2-4 %), at pH 9.0-11.0 9.0) 10-37 °C 28 °C). isolate contained meso-diaminopimelic acid, diagnostic sugars MK-9(H4) as...
Summary Clarifying glycosyltrasferases (GTs) function is of significance for the development GT inhibitors as drugs, and use GTs to glycodiversify small molecules in search drug leads. While many Actinomyces natural‐product had been functionally characterized, our understanding towards Bacillus so far very limited. Herein, genome‐wide identification macrolide genes from marine‐derived methylotrophicus B‐9987 revealed presence three bmmGT1 −3. was previously be involved biosynthesis trans...
A Gram-stain-negative, motile, aerobic and rod-shaped bacterial strain, designated T17T, was isolated from benthic sediment sampled at Jiaozhou Bay, Bohai Sea, China, its taxonomic position investigated. The 16S rRNA gene sequence of strain T17T exhibited the highest similarity values to those type Marinobacter lacisalsi FP2.5 (96.2 %) koreensis DD-M3T %). Strain grew optimally 35 °C, pH 7.0-8.0 in presence 6.0-10.0 % (w/v) NaCl. predominant ubiquinone identified as Q-9. major fatty acids...
Bacillus strains are widely distributed in terrestrial and marine environments, some of them used as biocontrol organisms for their biofilm-formation ability. In subtilis, biofilm formation is fine-tuned by a complex network, clear understanding which still requires study. bacteria, tmRNA, encoded the ssrA gene, catalyzes trans-translation that can rescue ribosomes stalled on mRNA transcripts lacking functional stop codon. tmRNA also affects physiological bioprocesses bacteria. this study,...
Successive planting is the main pattern for cultivating Chinese fir (Cunninghamia. lanceolata (Lamb.) Hook.). However, influence of this management has not been totally investigated, especially with respect to changes in soil microbial community and relationship properties. This study investigated physical chemical properties soil, its enzyme activities, diversity three adjoining plantations managed different successive models (long-term continuous growth without harvest, M1; single harvest...
Exploration of unstable compounds is a rarely explored area natural product research. We describe the integration genomic and metabolomic analyses with bioassay-guided compound mining to effectively explore bacillaenes. New bacillaene structures (2, 4, 5) were identified from mixtures using DANS-SVI (differential analysis 2D NMR spectrum–single spectrum variable intensities) method, which further verified by isolation pure under strictly controlled conditions. Compound 1 exhibited...
A Gram-stain-negative, non-motile, aerobic and ovoid-rod-shaped bacterial strain, designated as 2C3345T, was isolated from soil of a mangrove nature reserve in Shenzhen, PR China its taxonomic position investigated. The 16S rRNA gene sequence strain 2C3345T exhibited the highest similarity value to that type strains Thermomonas aquatica NBRC 113114T (98.4 %), carbonis KCTC 42013T (98.1 brevis DSM 15422T (98.0 %) haemolytica 13605T (97.9 %). Strain grew optimally at 28-30 °C, pH 7.0 without...
Daqu, integral to Baijiu production, substantially dictates the sensory characteristics of final product. GuaYi, denoted by white colonies on significantly influences its microbial composition and physicochemical attributes. The Daqu flavor quality are intrinsically linked extent GuaYi manifestation.In this study, we found Thermoascus Staphylococcus were enriched in LGY (Light Daqu), which thrived low moisture conditions primarily contributed degradation macromolecules like starch, reducing...