A5043022227- Peroxisome Proliferator-Activated Receptors
- Adolescent and Pediatric Healthcare
- Human-Animal Interaction Studies
- Blood properties and coagulation
- Platelet Disorders and Treatments
- Cholesterol and Lipid Metabolism
- Orthopedic Surgery and Rehabilitation
- Gestational Trophoblastic Disease Studies
- Hematological disorders and diagnostics
- Uterine Myomas and Treatments
- Venous Thromboembolism Diagnosis and Management
- Infant Health and Development
- Global Cancer Incidence and Screening
- Caveolin-1 and cellular processes
- Heparin-Induced Thrombocytopenia and Thrombosis
- Pediatric Pain Management Techniques
- Venomous Animal Envenomation and Studies
- Data-Driven Disease Surveillance
- Parvovirus B19 Infection Studies
- PI3K/AKT/mTOR signaling in cancer
- Infrared Thermography in Medicine
- Methemoglobinemia and Tumor Lysis Syndrome
- Hemophilia Treatment and Research
- Inflammatory Biomarkers in Disease Prognosis
- Mobile Health and mHealth Applications
Government Medical College
2023-2025
University of California, Davis
2014-2023
California State University, Sacramento
2022
Whipps Cross University Hospital
2021
University of Iowa
2020
Beth Israel Deaconess Medical Center
2020
UC Davis Health System
2019
UC Davis Comprehensive Cancer Center
2017
UC Davis Children's Hospital
2014
Michigan State University
2003-2010
Peroxisome proliferator-activated receptors (PPARs α, β, γ1, and γ2) are widely regarded as monitors of intracellular nonesterified fatty acid (NEFA) levels. As such, binding to PPAR leads changes in the transcription many genes involved lipid metabolism storage. Although composition NEFA pool is likely an important factor controlling activity, little information available on factors affecting its composition. Accordingly, we have examined effects exogenous acids PPARα activity rat primary...
This multicenter, parallel-group, randomized trial examined the effects of an animal-assisted intervention on stress, anxiety, and health-related quality life for children diagnosed with cancer their parents.Newly patients, aged 3 to 17 years (n = 106), were receive either standard care plus regular visits from a therapy dog (intervention group), or only (control group). Data collected at set points over 4 months child's treatment. Measures included State-Trait Anxiety Inventory™, Pediatric...
Liver X receptors (LXR) α and β play an important role in regulating the expression of genes involved hepatic bile fatty acid synthesis, glucose metabolism, as well sterol efflux. Studies with human embryonic kidney 293 cells indicate that unsaturated acids interfere oxysterols binding to LXR antagonize oxysterol-induced LXRα activity. In this report, we evaluated effects on LXR-regulated gene expression. The agonist, T1317, induced mRNAs encoding regulatory element-binding protein 1c...
Rabies is a fatal infectious disease caused by rabies lyssavirus, mainly transmitted to humans the bite of rabid mammals. can present in encephalitic and paralytic types. Paralytic presents with acute flaccid transverse myelitis. We report rare case inadequate post-exposure prophylaxis (PEP). A 19-year-old male was admitted paraplegia associated bladder bowel incontinence for 2 days. He had history Category III street stray dog received PEP 3 months back which revealed later. On imaging...
Fatty acids bind to and regulate the activity of peroxisome proliferator-activated (PPAR) liver X receptors (LXR). However, role lipid metabolism plays in control intracellular fatty acid ligands is poorly understood. We have identified two strains HEK293 cells that display differences regulation nuclear receptors. Using full-length Gal4-LBD chimeric functional assays, 20:4,n6 induced PPARα ∼2.2-fold suppressed LXRα by 80% (ED50 ∼25–50 μm) HEK293-E (early passage) but had no effect on or...
Summary. This study examined the effect of menorrhagia on quality life (QOL) adolescents. We used data from a survey 45 Using Pictorial Blood Assessment Chart (PBAC) and PBAC score ≥100 we identified adolescents likely to have menorrhagia. Our statistical analysis indicated that adversely affects QOL In this article discuss implications our future research avenues.
Increased awareness of von Willebrand Disease (VWD) has led to more frequent diagnostic laboratory testing, which insurers often dictate be performed at a facility with off-site processing, instead coagulation onsite processing. Off-site processing is prone preanalytical variables causing falsely low levels Factor (VWF) due the additional transport required. Our aim was determine percentage discordance between and specimen for VWD in this multicenter, retrospective study. We enrolled females...
Abstract Growing teratoma syndrome (GTS) is a condition in which mature with negative tumor markers arises at the site of treated malignant germ cell tumor. Pathogenic variants PTEN have been reported to cause autosomal dominant cancer predisposition syndromes and are associated tumors. We report association novel heterozygous pathogenic variant very early onset ovarian complicated by GTS as well overgrowth syndrome. This marks youngest patient developed following treatment her primary
The vitellointestinal/omphalomesenteric duct is embryonic structure connecting primary yolk sac to the midgut which obliterates by 10 th week of gestation. It may persist or incompletely obliterate form anomalies like Meckel’s diverticulum that most common and usually asymptomatic. Symptoms develop when involves complications such as hemorrhage, inflammation, perforation, it causes intussusception bowel obstruction. modalities useful in diagnosing are ultrasonography (USG) computed...
Kidney disease is a significant cause of mortality and morbidity worldwide. Important aspect reducing kidney health burden entails awareness about disease, for early detection management. Various organizations around the world have developed campaigns to increase awareness. The aim our study was find out public using Google Trends.
Venous thoracic outlet syndrome commonly results in arm swelling and pain as the subclavian vein is obstructed within inlet. We report use of ferumoxytol-enhanced contrast MRI diagnosis venous a male adolescent. In this patient who presented with right upper extremity thrombosis, chest was able to show both chronic thromboses dynamic occlusion veins abduction consistent Paget-Schroetter syndrome.
Background: MRI is an efcient approach for assisting in the diagnosis of chronic wrist pain. Due to its high resolution, multiplanar imaging capabilities & no use ionizing radiation, useful evaluating different ligaments, tendons, carpal tunnel, articular cartilage, and bone marrow joint. identication, characterization, staging osseous damage illness. This Material methods: cross sectional descriptive study performed tertiary care hospital during year 2021-22. In this study, 50...