A5101859470- Lipoproteins and Cardiovascular Health
- Immune Cell Function and Interaction
- Cancer Immunotherapy and Biomarkers
- Pediatric health and respiratory diseases
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Asthma and respiratory diseases
- Immune Response and Inflammation
- Gut microbiota and health
- Neurological Disease Mechanisms and Treatments
- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- Intensive Care Unit Cognitive Disorders
- Venous Thromboembolism Diagnosis and Management
- Immunotherapy and Immune Responses
- Cancer, Lipids, and Metabolism
- Colorectal Cancer Treatments and Studies
- Lubricants and Their Additives
- MicroRNA in disease regulation
- Advanced Welding Techniques Analysis
- Heparin-Induced Thrombocytopenia and Thrombosis
- Drug Transport and Resistance Mechanisms
- Natural Antidiabetic Agents Studies
- Advanced Biosensing Techniques and Applications
- Osteomyelitis and Bone Disorders Research
- IL-33, ST2, and ILC Pathways
Second Affiliated Hospital of Xi'an Jiaotong University
2025
Fu Wai Hospital
2016-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2015-2024
Affiliated Hospital of Guizhou Medical University
2021-2024
Guiyang Medical University
2021-2024
Chiang Mai University
2024
Shunde Polytechnic
2024
Jinan University
2023
Taiyuan University of Science and Technology
2023
Hebei Medical University
2023
Despite the widespread use of colistin sulfate (CS) in clinical settings China over recent years, supported by several studies demonstrating its efficacy, there remains a lack comparative data on efficacy and safety polymyxin B (PMB) versus CS, specifically for carbapenem-resistant Acinetobacter baumannii (CRAB)-caused nosocomial pneumonia. To compare PMB CS intensive care unit (ICU) patients with pneumonia caused CRAB. We conducted multicenter retrospective cohort study, including diagnosed...
Group 1 CD1 (CD1a, CD1b, and CD1c)–restricted T cells recognize mycobacterial lipid antigens are found at higher frequencies in Mycobacterium tuberculosis (Mtb)–infected individuals. However, their role dynamics during infection remain unknown because of the lack a suitable small animal model. We have generated human group transgenic (hCD1Tg) mice that express all three isoforms support development CD1–restricted with diverse cell receptor usage. Both immunization Mtb lipids elicit...
Aim. To evaluate the relation of proprotein convertase subtilisin-kexin type 9 (PCSK9) levels to coronary artery disease (CAD).
Interleukin-9 (IL-9) was reported as an active participant in the pathogenesis of allergic asthma. This study aimed to investigate major source ofIL-9 and its effect on interferon γ (IFN-γ) immunoglobulin (Ig) secretion by B cells. We isolated peripheral blood mononuclear cells from children with asthma healthy children. IL-9, IL-4 IFN-γ expression were detected ELISA, ELISpot Flowcytometry. Expression transcription factor PU.1 measured Western Blot. evaluated IL-9 cell activation Ig...
Human microbiota influence the response of malignancies to treatment with immune checkpoint blockade; however, their impact on other forms immunotherapy is poorly understood. This study explored effect blood clinical efficacy, represented by progression-free survival (PFS) and overall (OS), combined chemotherapy adoptive cellular therapy (ACT) in advanced colon cancer patients. Plasma was collected from colorectal patients (CRC) treated either alone (oxaliplatin capecitabine) (XELOX CT...
Abstract The process of myocardial hypertrophy in hypertension can lead to excessive activation oxidative stress. Lipoamide (ALM) has significant antioxidant and anti-inflammatory effects. This study aimed investigate the effects ALM on hypertension-induced cardiac hypertrophy, as well explore its underlying mechanisms. We evaluated spontaneously hypertensive rats rat cardiomyocytes treated with Ang II. found that was not effective lowering blood pressure SHR, but it attenuated...
Corrugated-flat rolling (CFR) process was employed to manufacture the Mg/Al clad plate at 400°C. The CFR can produce flat with excellent shape and corrugated interface. EBSD analysis tensile-shear tests were conducted study interface characteristics of plate, revealing its strengthening mechanism. After second-pass process, intermetallic compounds (IMCs) layer formed by heat treatment between passes broke, causing new bonding observed in gap fractured IMCs. Intermittently distributed IMCs...
Increased d-dimer is indicative of a hypercoagulable state and found to be associated with acute coronary syndromes. The present study aimed evaluate whether plasma levels could predict subsequent major clinical events in patients artery disease (CAD). First, 2209 angiographic-proven CAD were consecutively enrolled. Then, all subjected follow up for an average 18 months (ranged from 14 1037 days). relationships the severity future outcomes evaluated. We that was higher prior myocardial...
Background There is growing concern regarding elevated levels of circulating unmetabolized folic acid (UMFA) due to excessive intake (FA). However, no randomized clinical trial has been conducted examine the FA-UMFA dose-response relationship. Objective This study aimed investigate relationship in Chinese adults with hypertension and homocysteine (H-type hypertension), a population clear indication for FA treatment. Methods The data this were derived from randomized, double-blind,...
This study aimed to investigate the correlation between CT features and liver function p53 expression in hepatitis, cirrhosis hepatocellular carcinoma (HCC). Forty patients with HCC, 30 chronic hepatitis were enrolled December, 2015 2016. At same time, normal tissues collected from hepatic hemangioma used as control group. All scanned by CT. Average body surface area, left outer lobe caudate volume, proportions of whole calculated. Biochemical indexes determined. The pathological all...
Malachite green (MG), a triphenylmethane dye, is used in the aquaculture industry as disinfectant and insect repellent due to its potent bactericidal pesticidal properties. However, use poses potential environmental health risks. This study analyzed designed two haptens using computer simulation. Serum data confirmed feasibility of introducing an arm at dimethylamine group. Subsequently, highly selective monoclonal antibody strain was successfully prepared based on hapten. After optimizing...
Lipoprotein(a) [Lp(a)] is an emerging predictor for atherosclerotic cardiovascular disease (ASCVD) but the association from a perspective on current risk stratification was unknown. A cohort of 9944 Chinese patients with ASCVD recruited and refined into very-high-risk (VHR) non-VHR subgroups according to guideline. Lp(a) plasma levels were divided by its concentration (<30, 30-50, 50-75, ≥75 mg/dL) percentile zones (<25th, 25-50th, 50-75th, 75-90th, ≥90th). Cardiovascular events (CVEs)...