A5067267797- Colorectal Cancer Surgical Treatments
- Gastric Cancer Management and Outcomes
- Advanced biosensing and bioanalysis techniques
- Biosensors and Analytical Detection
- Cardiac Valve Diseases and Treatments
- Cardiac and Coronary Surgery Techniques
- Cancer-related molecular mechanisms research
- Metabolism, Diabetes, and Cancer
- Atrial Fibrillation Management and Outcomes
- Metastasis and carcinoma case studies
- Cancer Genomics and Diagnostics
- Cancer, Hypoxia, and Metabolism
- Colorectal Cancer Treatments and Studies
- Lipoproteins and Cardiovascular Health
- Cardiac Imaging and Diagnostics
- RNA modifications and cancer
- Advanced Biosensing Techniques and Applications
- 14-3-3 protein interactions
- Genetic factors in colorectal cancer
- Diverticular Disease and Complications
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Intraperitoneal and Appendiceal Malignancies
- Surgical site infection prevention
- Anatomy and Medical Technology
- Esophageal Cancer Research and Treatment
Fujian Medical University
2017-2024
Fujian Provincial Hospital
2017-2024
Fuzhou University
2020-2024
Southern Medical University
2019-2022
Nanfang Hospital
2019-2022
International Culture University
2020
Tongji University
2009-2011
Tongji Hospital
2011
Abstract The current tumour-node-metastasis (TNM) staging system alone cannot provide adequate information for prognosis and adjuvant chemotherapy benefits in patients with gastric cancer (GC). Pathomics, which is based on the development of digital pathology, an emerging field that might improve clinical management. Herein, we propose a pathomics signature (PS GC ) derived from multiple features haematoxylin eosin-stained slides. We find PS independent predictor prognosis. A nomogram...
Lymph node status is the primary determinant in treatment decision making early gastric cancer (EGC). Current evaluation methods are not adequate for estimating lymph metastasis (LNM) EGC.To develop and validate a prediction model based on fully quantitative collagen signature tumor microenvironment to estimate individual risk of LNM EGC.This retrospective study was conducted from August 1, 2016, May 10, 2018, at 2 medical centers China (Nanfang Hospital Fujian Provincial Hospital)....
Background: Atrial fibrillation (AF) after coronary artery bypass grafting (CABG) is still the most common postoperative arrhythmic complication. Previous studies report that patients undergoing preoperative statin therapy had a lower incidence of AF. This study aimed to assess effect atorvastatin on preventing AF following off-pump CABG in randomized, controlled trial. Methods and Results: The 140 consecutive elective CABG, without history or previous treatment, were enrolled randomly...
Atrial fibrillation (AF) is one of the most common postoperative arrhythmias in patients who undergo coronary artery bypass grafting (CABG). The aim this study was to evaluate effect preoperative atorvastatin on atrial following with cardiopulmonary (CCABG). One hundred consecutive undergoing elective CCABG, without history AF or previous statin treatment, were enrolled and randomly assigned a group (atorvastatin 20 mg/d, n = 49) control (placebo, 51) starting 7 days preoperatively. primary...
An innovative quartz crystal microbalance immunoassay was designed for detection of carcinoembryonic antigen using horseradish peroxidasenanoparticle as the enhancer, accompanying enzymatic biocatalytic precipitation toward 4-chloro-1-naphthol.
The current TNM staging system provides limited information for prognosis prediction and adjuvant chemotherapy benefits patients with gastric cancer (GC).To develop a tumor-associated collagen signature of GC (TACSGC) in the tumor microenvironment to predict GC.This retrospective cohort study included training 294 consecutive treated between January 1, 2012, December 31, 2013, from Nanfang Hospital, Southern Medical University, People's Republic China, validation 225 October 2010, Fujian...
Herein, we reported a novel photoelectrochemical immunoassay method based on target-triggered on/off signal of the ultra-structured Bi2O2S (BOS) photoanode system for sensitive testing carcinoembryonic antigens (CEAs) in serum samples. Well-defined three-dimensional sheet-like self-assembled flower-like superstructures were obtained using time-controlled hydrothermal method. Such well-shaped multifaceted surfaces considered to be good laser cavity mirror reflection and refraction excitation...
Gastric cancer is one of the most common and deadly types worldwide, which brings millions dollars economic loss each year. Patients diagnosed with early-onset gastric were reported to have a worse prognosis compared other patients, while mechanisms behind such phenomenon are unknown. To identify age-dependent somatic alternations in cancer, next-generation sequencing targeting 425 genes was performed on 1688 tumor tissues corresponding plasma samples. In our study, microsatellite...
Background: FNDC5 belongs to the family of proteins called fibronectin type III domain-containing which carry out a variety functions. The expression is associated with occurrence and development tumors. However, role in gastric cancer remains relatively unknown. Methods: In research, its value for prognosis patients were observed TCGA database GEO datasets patients. regulation cells proliferation, invasion, migration was determined. WGCNA Enrichment analysis performed on genes co-expressed...
The present study aimed to investigate the expression and prognostic significance of insulin-like growth factor binding protein 6 (IGFBP-6) in gastric adenocarcinoma. IGFBP-6 was examined 263 specimens from adenocarcinoma patients using reverse transcription-quantitative polymerase chain reaction (RT-qPCR), western blotting immunohistochemical (IHC) staining. association between expression, clinicopathological factors clinical outcomes investigated. Akaike information criterion (AIC)...
The present study was aimed to investigate the value of serum amyloid A in early diagnosis infection patients with extracorporeal circulation and evaluate prognosis patients. This a prospective observational study. Patients admitted intensive care unit after cardiopulmonary bypass surgery between January 2017 2019 were continuously collected. Daily blood traditional inflammatory markers (white cell, C-reactive protein procalcitonin) monitored 1 day before 3 days surgery. efficacy indicators...
e15222 Background: Multiple biomarkers are thought to be effective guides in selecting immune checkpoint inhibitors, such as Tumor mutational burden (TMB), PD-L1 and MSI/dMMR. Immunotherapy may miraculous some patients but many other experienced poor prognosis even tumor overgrowth after immunotherapy real practice. Previous studies have reported that 11q13 (CCND1, FGF3, FGF4, FGF19) amplifications were associated with HPD. However, the characterization of chromosome amplification Chinese...
Objective To investigate the safety and feasibility of laparoscopic appendectomy (LA) in patients with high-risk complicated appendicitis. Methods The clinical data 1 032 appendicitis, who were treated between June 2008 2015, analyzed retrospectively. Based on American Association Anesthesiologists (ASA) scoring criteria, 168 ASA score 3-4 included. According to surgical options, all divided into LA group (n=98) open (OA group, n=70) . The preoperative preparation time, operation...