A5100686513- Influenza Virus Research Studies
- Tuberculosis Research and Epidemiology
- SARS-CoV-2 and COVID-19 Research
- Mycobacterium research and diagnosis
- COVID-19 Clinical Research Studies
- Pediatric health and respiratory diseases
- Medical Research and Treatments
- CAR-T cell therapy research
- COVID-19 diagnosis using AI
- Mosquito-borne diseases and control
- Diagnosis and treatment of tuberculosis
- Inflammation biomarkers and pathways
- Immunotherapy and Immune Responses
- Clostridium difficile and Clostridium perfringens research
- Respiratory viral infections research
- Fungal Infections and Studies
- Lung Cancer Treatments and Mutations
- Immune Cell Function and Interaction
- vaccines and immunoinformatics approaches
- Gut microbiota and health
- Acute Lymphoblastic Leukemia research
- Studies on Chitinases and Chitosanases
- Vector-borne infectious diseases
- Antifungal resistance and susceptibility
- Viral Infections and Vectors
University of Science and Technology of China
2025
Sun Yat-sen University
2009-2021
Fifth Affiliated Hospital of Sun Yat-sen University
2009-2021
The University of Sydney
2021
Centenary Institute
2021
Metagenomic next-generation sequencing (mNGS) is an effective diagnostic method for infectious diseases, however, its clinical utility tuberculosis (TB) diagnosis remains to be demonstrated.A total of 322 bronchoalveolar lavage fluid (BALF) samples were collected from 311 suspected and confirmed pulmonary TB patients tested by mNGS, acid-fast bacillus (AFB) smear microscopy, Xpert® MTB/RIF (Xpert), mycobacterium culture bacterial/fungal culture. Diagnostic performance mNGS was compared with...
Abstract Background There is an urgent need to better understand the novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), for that disease 2019 (COVID-19) continues cause considerable morbidity and mortality worldwide. This paper was differentiate COVID-19 from other infectious diseases such as avian-origin influenza A (H7N9) (H1N1) virus infections. Methods We included patients who had been hospitalized with laboratory-confirmed infection by SARS-CoV-2 ( n = 83),...
Understanding the dynamics of lung microbiota in tuberculosis patients, especially those who cannot be confirmed bacteriologically clinical practice, is imperative for accurate diagnosis and effective treatment. This study aims to characterize distinct microbial features between negative patients understand influence on patients. We collected specimens bronchoalveolar lavage fluid from 123 Samples were subjected metagenomic next-generation sequencing reveal signatures. By combining...
Abstract Triggering receptor expressed on myeloid cells 1 (TREM-1) is a mainly cells, and it plays an important role in modulating immune response against infectious agents. The function of TREM-1 nonmyeloid such as Vδ2 T has not been characterized, their pulmonary tuberculosis (TB) remains unclear. To assess the expression blood from TB patients investigate its mechanism induction, we exploited flow cytometry analysis to study active control subjects. In this demonstrate that (TREM-1+)...
Histoplasmosis is an endemic disease mainly occurring in North America and rare China. Confirmation of histoplasmosis should be based on a compatible clinical scenario positive culture or histopathology. However, there are still many cases that misdiagnosed missed, especially individuals from non-endemic areas. In recent years, metagenomic next-generation sequencing (mNGS) has led to the accurate timely diagnosis some complicated infectious diseases. We describe case 27-year-old Chinese man...
Background: An outbreak of SARS-CoV-2 infections began in Wuhan, China, and quickly spread to the entire country. We sought delineate time features clinical symptoms, virological conversion, chest radiological abnormalities individuals infected with this virus Zhuhai, China. Methods: In retrospective study, we assessed 85 confirmed cases COVID-19 Fifth Hospital Sun Yat-sen University, from 17th January 11th February 2020. Outcomes were followed up until 24th Results: The median age patients...
Objective To investigate the apearance and characteristics of skin rashes in patients suffering from dengue fever.Methods Clinical data were retrospectively analyzed for 126 hospitalized with fever collected August to October,2007.Results Out fever,69.0% (87/126)had rashes,which usually developed day 1 11 after fever.About 59.7%(52/87)of these 3 7 fever.No eruption order was evidenced 59(67.8%)patients.Skin located both trunk limbs 38(43.7%)patients,and only 30 (34.5%)patients.The incidence...