A5032299417- Asthma and respiratory diseases
- Allergic Rhinitis and Sensitization
- Food Allergy and Anaphylaxis Research
- Drug-Induced Adverse Reactions
- Dermatology and Skin Diseases
- Pharmaceutical studies and practices
- Child Nutrition and Water Access
- Contact Dermatitis and Allergies
- Respiratory and Cough-Related Research
- Inhalation and Respiratory Drug Delivery
- SARS-CoV-2 and COVID-19 Research
- Pediatric health and respiratory diseases
- Birth, Development, and Health
- Gut microbiota and health
- Respiratory viral infections research
- Dermatological diseases and infestations
- Urticaria and Related Conditions
- Global Maternal and Child Health
- Transgenic Plants and Applications
- Pharmacovigilance and Adverse Drug Reactions
- Immunotherapy and Immune Responses
- Child and Adolescent Health
- Probiotics and Fermented Foods
- Infant Health and Development
- Obesity, Physical Activity, Diet
Prince of Songkla University
2016-2025
Siriraj Hospital
2021
Pediatrics and Genetics
2019
Songklanagarind Hospital
2013-2015
Mahidol University
2000
Effective vaccine coverage is urgently needed to tackle the COVID-19 pandemic. Inactivated vaccines have been introduced in many countries for emergency usage, but only provided limited protection. Heterologous vaccination a promising strategy maximise immunogenicity. Here, we conducted phase I, randomised control trial observe safety and immunogenicity after an intradermal boost, using fractional dosage (1:5) of BNT162b2 mRNA healthy participants Songkhla, Thailand. In total, 91 volunteers...
Atopic dermatitis (AD), a chronic, relapsing dermatitis, is characterized by dry and pruritus skin in patients with personal or family history of atopy. It affects up to 20% children 1-3% adults most countries worldwide, leads significant treatment costs morbidity. These guidelines are developed accordance evidence-based publications expert opinions. Following simple algorithms, the aim assist adult pediatric physicians better care AD. As other diseases, there have been several diagnosis...
Fish allergy is the third most common food after milk and egg in parts of Europe, but there little data about prevalence South East Asia where it an important part regular diets.We aimed to obtain estimate population fish among older children Philippines, Singapore Thailand.The 14- 16-year-old 3 countries was evaluated using a structured written questionnaire which distributed students randomly selected secondary schools. An extended determine convincing on basis typical clinical...
Previous studies provide evidence for an association between modifications of the gut microbiota in early life and development food allergies. We studied faecal composition (16S rRNA gene amplicon sequencing) microbiome functionality (metaproteomics) a cohort 40 infants diagnosed with cow's milk allergy (CMA) when entering study. Some showed outgrowth CMA after 12 months, while others did not. Faecal was analysed directly diagnosis (baseline) as well 6 months The aim to gain insight on...
Allergic rhinitis (AR) and chronic urticaria impose significant socioeconomic burdens on lower-income countries. Despite the availability of evidence-based guidelines, their implementation varies, comprehensive data these allergic conditions are notably lacking in Thailand. We sought to describe current management strategies for AR The Allergy, Asthma, Immunology Association Thailand used a modified Delphi method explore consensus urticaria. Clinicians with expertise provided input through...
Using the same questionnaire as in ISAAC Phase One study conducted 1995, Three was carried out Bangkok and Chiang Mai, Thailand, 2001, among children aged 6–7 13–14 years. There an increase prevalence of three diseases younger age group, i.e., current asthma, rhinitis, rhinoconjunctivitis, flexural eczema. In older rhinitis rhinoconjunctivitis increased. no change asthma Bangkok, but decreased Mai. Prevalence eczema increased remained
Allergic reactions to medication range from mild severe or even life-threatening. Proper documentation of patient allergy information is critical for safe prescription, avoiding drug interactions, and reducing healthcare costs. Allergy regularly obtained during the medical interview, but often poorly documented in electronic health records (EHRs). While many EHRs allow structured adverse reaction (ADR) reporting, a free-text entry still common. The resulting neither interoperable nor easily...
Increasing exposure of children and adolescents to electronic media is a worldwide phenomenon, including in Thailand. To date, few studies examine game play Thai adolescents. Our research describes the prevalence examines associations between time spent engaged school performance Hat-Yai municipality. A cross-sectional study was conducted among 1,492 from four secondary schools one commercial college January through March 2007, using questionnaires for collecting information about...
Previous house dust mite subcutaneous immunotherapy (HDM SCIT) placebo-controlled trials have small sample sizes and lack a consensus on baseline treatment.
Abstract Objective To determine iodine intake and urinary excretion (UIE) in a group of pregnant Thai women the concentration thyroid-stimulating hormone (TSH) their neonates. Design A prospective cohort study. Setting Three districts Songkhla, southern Thailand. Subjects Two hundred thirty-six women. Results quarter participants lacked knowledge prevention deficiency, although 70 % used iodized salt. Those who did not use salt stated that they had no about (57 %) was sold village (36 %)....
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global pandemic. Two doses of an inactivated SARS-CoV-2 vaccine (CoronaVac) have been shown to be insufficient protect against variants concern (VOCs), while viral vector vaccines remain protective the infection. Herein, we conducted preliminary study evaluate safety and immunity in adult population who received conventional dosage-regimen vaccine; with additional intradermal ChAdOx1 nCoV-19 reciprocal dosage (1:5). An...
Abstract Aim The association between adiposity rebound and insulin resistance in middle childhood has seldom been studied. We examined the effect of body mass index ( BMI ) velocity early on prepubertal children. Methods data from a longitudinal follow‐up birth cohort Thailand were used. homoeostatic model assessment HOMA ‐ IR was calculated 12‐hour fasting plasma glucose serum at eight‐and‐a‐half years age. four periods: zero to one, one three, three six A multiple linear regression used...
Under-5-years child mortality remains high in rural China. Integrated management of childhood illness (IMCI) was introduced to China 1998, but only a few areas have been included. This study aimed at assessing the current situation health system care and evaluating clinical competency village doctors illnesses prior implementing IMCI programme remote border areas.The carried out Puer prefecture Yunnan province. There were 182 list bureau these areas. Of these, 154 (84.6%) recruited into...
A practical booster vaccine is urgently needed to control the coronavirus disease (COVID-19) pandemic. We have previously reported safety and immunogenicity of a fractional intradermal booster, using BNT162b2 mRNA in healthy volunteers who had completed two doses inactivated SARS-CoV-2 vaccine. In this study, an intramuscular at full dosage was used as control, half-dose vaccination included for reciprocal comparison. Detailed T-cell studies are essential understand cellular responses...
An imbalanced prevalence of allergic diseases occurs in the region South East Asia. It has been suggested that a change lifestyle associated with improved hygiene and modernization altered composition human gastrointestinal microbiota, hence susceptibility to allergy. This cross-sectional study was designed investigate differences between fecal microbiota children living areas contrasting socioeconomic development. Fecal samples from 73 young (age 3.0 ± 0.5) rural Thailand 69 age-matched...
Abstract Introduction Laggera pterodonta , a traditional Chinese medicine, has been commonly used in respiratory tract infections for more than hundreds of years without any randomized controlled trials to evaluate its efficacy and safety. Objectives To the safety hospitalized children aged 3–24 months with acute bronchiolitis. Methods A double‐blind, randomized‐controlled trial was conducted three tertiary hospitals Kunming, China. total 133 bronchiolitis an initial episode wheezing were...
Component-resolved diagnostics (CRD) have garnered a lot of attention in recent years the diagnosis food allergies. We aimed to investigate sensitization against cow's milk and egg white components, study clinical usefulness serum food-specific immunoglobulin E (sIgE) components Thai children with allergies.Children IgE-mediated and/or allergy were enrolled. Clinical reactions determined. Specific IgE milk, white, alpha-lactalbumin (ALA), beta-lactoglobulin (BLG), casein, ovomucoid,...
An inspection of the sewing unit in a 700-bed hospital revealed that workers employed this complained cough, shortness breath, and tightness chest. The aim cross-sectional study was to assess prevalence respiratory symptoms dust concentration workplace. obtained results were compared with control group.The (n = 22, including 19 current 3 former employees) 22 housekeepers as controls included study. All participants responded questionnaire underwent spirometric measurements, skin prick test,...