Lei Xie

ORCID: 0000-0002-2303-9173
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About
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Research Areas
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Tryptophan and brain disorders
  • Graphene and Nanomaterials Applications
  • Stress Responses and Cortisol
  • Scientific Computing and Data Management
  • Bone Tissue Engineering Materials
  • Ferroptosis and cancer prognosis
  • Software-Defined Networks and 5G
  • Network Traffic and Congestion Control
  • Advanced Optical Network Technologies
  • Urinary Bladder and Prostate Research
  • Pneumonia and Respiratory Infections
  • Astrophysics and Cosmic Phenomena
  • Neuroscience and Neuropharmacology Research
  • Hepatitis B Virus Studies
  • Advanced Fiber Laser Technologies
  • Nanoparticles: synthesis and applications
  • Enhanced Recovery After Surgery
  • Cognitive Radio Networks and Spectrum Sensing
  • Automotive and Human Injury Biomechanics
  • Reproductive Biology and Fertility
  • Web Application Security Vulnerabilities
  • Nigella sativa pharmacological applications
  • Phytoestrogen effects and research
  • Inflammation biomarkers and pathways

University of Electronic Science and Technology of China
2012-2025

Tongji Hospital
2022-2024

Huazhong University of Science and Technology
2022-2024

Shantou University
2024

First Affiliated Hospital of Shantou University Medical College
2024

Third Hospital of Hebei Medical University
2024

Hebei Medical University
2024

Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
2024

Southwest Jiaotong University
2023

Chengdu University of Traditional Chinese Medicine
2023

Software defined network (SDN) can effectively improve the performance of traffic engineering and will be widely used in backbone networks. Therefore, new energy-saving schemes must take SDN into consideration; this action is extremely important owing to rapidly increasing energy consumption telecom Internet service provider (ISP) Meanwhile, introduction current networks incremental most cases, for technical economic reasons. During period, operators manage hybrid which traditional protocols...

10.1109/jcn.2016.000079 article EN Journal of Communications and Networks 2016-08-01

Microglia are involved in sleep/wake cycles and the response to sleep loss. Synaptic pruning by microglia is necessary for central nervous system circuit refinement contributes cognitive function. Here, we investigated whether how microglia-mediated synaptic may be deficits induced deprivation mice. Mice were deprived of leaving them a spontaneously rotating rod 72 h, after which their function was assessed using an object location test, Y maze, novel recognition test. Sleep lowered...

10.1016/j.ynstr.2023.100553 article EN cc-by-nc-nd Neurobiology of Stress 2023-06-25

Code review remains a critical yet resource-intensive process in software development, particularly challenging large-scale industrial environments. While Large Language Models (LLMs) show promise for automating code review, existing solutions face significant limitations precision and practicality. This paper presents BitsAI-CR, an innovative framework that enhances through two-stage approach combining RuleChecker initial issue detection ReviewFilter verification. The system is built upon...

10.48550/arxiv.2501.15134 preprint EN arXiv (Cornell University) 2025-01-25

Anti-angiotherapy (Bevacizumab) is currently regarded as a promising option for glioma patients who are resistant to temozolomide (TMZ) treatment. But ongoing clinical research failed meet therapeutic expectations. This study aimed explore the pivotal genetic feature responsible TMZ and Bevacizumab resistance in patients.We downloaded transcriptomic methylation data of from The Cancer Genome Atlas (TCGA), Chinese Glioma (CGGA), Gene Expression Omnibus (GEO) databases grouped these into...

10.3389/fonc.2021.769592 article EN cc-by Frontiers in Oncology 2021-12-17

Abstract The Large High Altitude Air Shower Observatory (LHAASO) is located in Haizi Mountain, Daocheng County, Sichuan Province, with an average altitude of 4410 m. Wide Field view Cherenkov Telescope Array (WFCTA) one its three observation arrays. Laser calibration system for WFCTA consists 2 nitrogen lasers and 1 Nd:YAG laser system. During the operation WFCTA, outdoor temperature may dropped from 17 °C to about -30 °C, which will bring serious challenges operating field. In order ensure...

10.1088/1748-0221/18/06/t06008 article EN Journal of Instrumentation 2023-06-01

Abstract Aloe‐emodin (AE) has been shown to inhibit the proliferation of several cancer cell lines, including human nasopharyngeal carcinoma (NPC) lines. In this study, we confirmed that AE inhibited malignant biological behaviors, viability, abnormal proliferation, apoptosis, and migration NPC cells. Western blotting analysis revealed upregulated expression DUSP1, an endogenous inhibitor multiple cancer‐associated signaling pathways, resulting in blockage extracellular signal‐regulated...

10.1002/ptr.7793 article EN Phytotherapy Research 2023-03-03

10.1016/j.nima.2023.168759 article EN Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated Equipment 2023-10-07

The leaves of L. japonica (LLJ) are widely used as medicine in China. It is rich caffeoylquinic acids, flavonoids and iridoid glycosides has strong reducing capacities. Therefore, it can be a green material to synthesize silver nanoparticles.LLJ was agent produce the LLJ-mediated nanoparticles (LLJ-AgNPs). structure physicochemical properties LLJ-AgNPs were characterized by ultraviolet spectroscopy (UV-Vis), scanning electron microscopy (SEM), transmission (TEM), Fourier transform infrared...

10.2147/ijn.s356919 article EN cc-by-nc International Journal of Nanomedicine 2022-04-01

Limited data are available on the characteristics, risk factors, and antimicrobial treatment of critically ill pediatric patients with carbapenem-resistant Enterobacteriaceae (CRE) infections. This study was to identify factors for 30-day mortality in intensive care unit (PICU) CRE infections compare clinical outcomes different regimens.A retrospective, observational cohort performed admitted PICU positive cultures between January 2016 December 2021.For 56 patients, overall 50% (n=28)....

10.2147/idr.s394283 article EN cc-by-nc Infection and Drug Resistance 2022-12-01

Hepatocellular carcinoma (HCC) is the most common liver malignancy where tumorigenesis and metastasis are believed to be tied hallmarks of hypoxia tumor microenvironment (TME).In this study, investigate relationships among hypoxia, TME, HCC prognosis, we collected two independent datasets from a public database (TCGA-LIHC for identification, GSE14520 validation) identified hypoxia-related differentially expressed genes (DEGs) TCGA data, univariable Cox regression lasso analyses were...

10.2174/1573409919666221223123610 article EN Current Computer - Aided Drug Design 2022-12-26
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