A5103083840- Vascular Tumors and Angiosarcomas
- IgG4-Related and Inflammatory Diseases
- Neuroendocrine Tumor Research Advances
- Eosinophilic Disorders and Syndromes
- Lymphoma Diagnosis and Treatment
- Viral-associated cancers and disorders
- Gastrointestinal disorders and treatments
- Liver Disease Diagnosis and Treatment
- Advances in Oncology and Radiotherapy
- Liver Diseases and Immunity
- Ear and Head Tumors
- AI in cancer detection
- Hepatitis C virus research
- Tattoo and Body Piercing Complications
- Pharmacological Effects and Toxicity Studies
- Protein Tyrosine Phosphatases
- Pancreatic and Hepatic Oncology Research
- Moyamoya disease diagnosis and treatment
- Galectins and Cancer Biology
- Pituitary Gland Disorders and Treatments
- Colorectal Cancer Screening and Detection
- Neurological Complications and Syndromes
- Phagocytosis and Immune Regulation
- Eosinophilic Esophagitis
- Cholangiocarcinoma and Gallbladder Cancer Studies
Kurashiki Central Hospital
2008-2022
Okayama University
2016-2020
Himeji Red Cross Hospital
2011
Histopathological diagnosis of pancreatic ductal adenocarcinoma (PDAC) on endoscopic ultrasonography-guided fine-needle biopsy (EUS-FNB) specimens has become the mainstay preoperative pathological diagnosis. However, EUS-FNB specimens, accurate histopathological evaluation is difficult due to low specimen volume with isolated cancer cells and high contamination blood, inflammatory digestive tract cells. In this study, we performed annotations for training sets by expert pathologists trained...
Hypereosinophilic syndrome (HES) encompasses both myeloproliferative and lymphoproliferative diseases. We encountered a rare case of lymphocytic HES followed by malignant T cell lymphoma, who was diagnosed as eosinophilic pneumonia upon the first visit. During clinical course, transition chest CT findings from bilateral multifocal ground-glass opacities consolidations to scattered multiple small nodules impressive suggestive. Given increased risk developing T-cell patients with (especially...
The utility of gastric biopsy for diagnosing immunoglobulin (Ig)G4-related gastrointestinal disease (IgG4-GID) remains unclear. Bottom-heavy plasmacytosis (BHP) is a distinct feature IgG4-GID. To clarify the feasibility using biopsies to diagnose BHP in IgG4-GID, we analyzed histological features and immunostaining specimens from 31 known IgG4-related (IgG4-RD) patients assessed presence 1696 consecutive routine biopsies. Cases with both >10 IgG4-positive plasma cells per high-power field an...
Abstract Dilated vessels at the ulcer floor of second part duodenum can be signs pancreatic arteriovenous malformation; contrast‐enhanced computed tomography should performed, and surgical treatment considered.
Age-related Epstein-Barr virus (EBV)-positive B-cell lymphoproliferative disorder (LPD) occurs in elderly patients without immunodeficiency. An 81-year-old woman any known immunodeficiency was examined for fever, rash, arthritis, thrombocytopenia, pleural and pericardial effusions, lymphadenopathy, positive autoantibodies, which satisfied the classification criteria systemic lupus erythematosus (SLE). However, a lymph node biopsy revealed EBV-LPD, she diagnosed with age-related EBV-LPD. In...
症例は6歳，男児．初発のネフローゼ症候群として，プレドニゾロン（PSL）の投与を開始し，2週間後より血圧が上昇傾向となったためカルシウム拮抗薬の投与を開始した．PSL投与開始から4週間後も完全寛解に至らず，腎生検を施行し，巣状分節性糸球体硬化症と病理診断した．腎生検の翌日，収縮期血圧120 mmHg台で，意識障害と左共同偏視があり，可逆性後頭葉白質脳症と診断した．ニカルジピンの持続投与を開始，ミダゾラムの持続静注に加えホスフェニトイン，フェノバルビタールを投与し，持続脳波モニタリングを行った．脳波上のてんかん発射は減少傾向となり，意識障害は回復，画像所見も改善した．アンジオテンシン変換酵素阻害薬を追加し，収縮期血圧100 mmHg前後となった．PSLは漸減中止し，U-TP/Cr 0.5 g/g·Cr以下で経過した．小児腎疾患患者ではPRES発症に関するリスク因子を多く有しており，著明な高血圧や免疫抑制剤の内服がなくても発症する場合があるため注意が必要である．
症例は59歳，男性。半年前より右肩に腫瘤が出現し，1ヵ月後に一度消退した。その後，数週間の間に再度急速な増大を認めた。初診時，外方性に発育する60mm大の緊満した腫瘍を認めた。手術時の所見では深筋膜への浸潤はなく，皮下組織層まで切除した。術後の病理組織学的検査では悪性腫瘍である診断はついたものの，詳細な診断には外部へのコンサルテーションのため時間を要していた。その間にも術後13日目には創部に再発を示唆する発赤を認めた。急速に増大する腫瘍であったことからも，早急に拡大切除を行う必要を考え，初回切除から21日目に再手術を行った。前回の手術瘢痕周囲に出現した発赤から2cmのマージンを取って切除し，下床は僧帽筋まで含めて一塊に切除し，傍肩甲皮弁で再建した。病理組織学的検査にてpleomorphic dermal sarcoma（以下 PDS）と診断した。術後13ヵ月時点で局所再発や転移は認めていない。