Almudena Alonso‐Ojembarrena

ORCID: 0000-0002-2413-9758
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About
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Research Areas
  • Ultrasound in Clinical Applications
  • Neonatal Respiratory Health Research
  • Congenital Diaphragmatic Hernia Studies
  • Respiratory Support and Mechanisms
  • Neonatal and Maternal Infections
  • Pleural and Pulmonary Diseases
  • Phonocardiography and Auscultation Techniques
  • Congenital Heart Disease Studies
  • Pneumonia and Respiratory Infections
  • Airway Management and Intubation Techniques
  • Neonatal Health and Biochemistry
  • Sepsis Diagnosis and Treatment
  • Neuroscience of respiration and sleep
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Nosocomial Infections in ICU
  • Atomic and Subatomic Physics Research
  • Cytomegalovirus and herpesvirus research
  • Kawasaki Disease and Coronary Complications
  • Infant Development and Preterm Care
  • Parvovirus B19 Infection Studies
  • Retinopathy of Prematurity Studies
  • Retinal Diseases and Treatments
  • Cardiac, Anesthesia and Surgical Outcomes
  • Central Venous Catheters and Hemodialysis
  • Respiratory viral infections research

Hospital Universitario Puerta del Mar
2012-2024

Biomedical Research and Innovation Institute of Cadiz
2020-2024

Hospital Clínic de Barcelona
2022

Hospital Universitario La Paz
2022

Complejo Asistencial Universitario de Palencia
2022

Universidad de Cádiz
2021

Universitat de Barcelona
2019

Hospital de Sant Pau
2019

Centro Nacional de Microbiologia
2011

Instituto de Salud Carlos III
2011

Abstract Background Lung ultrasound (LU) has been widely used to diagnose and monitor acute lung diseases in neonates, but its role chronic not elucidated. Objective We aim describe the evolution of a score (LU score) very low birth weight infants (VLBWI) with without bronchopulmonary dysplasia (BPD). Methods prospectively included 59 VLBWI performed LU first 24 72 hours life, then weekly until 36 weeks´ postmenstrual age (PMA). calculated as semiquantitative representing aeration (0‐3)...

10.1002/ppul.24410 article EN Pediatric Pulmonology 2019-06-10

Importance Surfactant administration may be needed in late preterm through full-term neonates, but the pathophysiology of their respiratory failure can different from that early neonates. The lung ultrasonography score (LUS) is accurate to guide surfactant replacement our knowledge, it has not yet been studied neonatal population. Objective To assess whether LUS equally predict need neonates as Design, Setting, and Participants This prospective, international, multicenter diagnostic study...

10.1001/jamanetworkopen.2024.13446 article EN cc-by-nc-nd JAMA Network Open 2024-05-28

Lung ultrasound (LUS) is now widely used in the diagnosis and monitor of neonatal lung diseases. Nevertheless, published literatures, LUS images may display a significant variation technical execution, while scanning parameters influence diagnostic accuracy. The inter- intra-observer reliabilities exam have been extensively studied general LUS. As expected, reliability declines hands novices when they perform point-of-care (POC US). Consequently, having appropriate guidelines regarding to...

10.1080/14767058.2021.1940943 article EN cc-by-nc-nd The Journal of Maternal-Fetal & Neonatal Medicine 2021-06-28

Objective Regarding the use of lung ultrasound (LU) in neonatal intensive care units (NICUs) across Europe, to assess how widely it is used, for what indications and its implementation might be improved. Design intervention International online survey. Results Replies were received from 560 NICUs 24 countries between January May 2023. LU uptake varied considerably (20%–98% NICUs) countries. In 428 (76%), was used clinical indications, while 34 (6%) only research purposes. One-third had <2...

10.1136/archdischild-2024-327068 article EN Archives of Disease in Childhood Fetal & Neonatal 2024-04-11

In many cases, assisted respiratory support is needed to ensure the survival of premature infants. The present study focused on evaluating noise exposure experienced by newborns under CPAPa means a neonatal helmet compare discomfort measured in one-third octave bands, terms curve 40 phons, and analyzing influence that HMEb filter placed helmets have during delivery oxygen-air, levels sound pressure. Likewise, pressure quantified at ear level, linear thirds octaves, depending air-oxygen flow...

10.3813/aaa.918638 article EN Acta acustica united with Acustica 2013-06-25

New ultrasound measurements to diagnose diaphragmatic dysfunction, including shortening fraction (DSF), have been studied in adults and children, but there are no data on reference values for neonates.To describe DSF term neonate (TN) preterm (PTN), calculate its reproducibility.We included asymptomatic TN PTN during their first 24 hours of life. We measured at the zone apposition both hemithoraces. Reproducibility image acquisition, inter- intra-rater agreement were calculated among an...

10.1002/ppul.24866 article EN Pediatric Pulmonology 2020-05-27

Lung ultrasound is a useful tool for diagnosis and follow-up of diseases in critically ill neonates. Its use increasingly widespread thanks to its advantages over other imaging tests the rapidly growing body evidence support it, "point-of-care ultrasound" (POCUS) has become key component neonatal guidelines. The objective this special article present foundations established diagnostic therapeutic applications lung ultrasonography as well introducing new applications.The Ultrasound Section...

10.1016/j.anpede.2022.01.002 article EN cc-by-nc-nd Anales de Pediatría (English Edition) 2022-03-01

The management of respiratory distress syndrome (RDS) in premature newborns is based on different types non-invasive support and surfactant replacement therapy (SRT) to avoid mechanical ventilation as it may eventually result lung damage. European guidelines currently recommend SRT only when the fraction inspired oxygen (FiO2) exceeds 0.30. literature describes that early decreases risk bronchopulmonary dysplasia (BPD) mortality. Lung ultrasound score (LUS) preterm infants affected by RDS...

10.1186/s13063-023-07745-8 article EN cc-by Trials 2023-11-04

Abstract Objective Current international guidelines on neonatal respiratory distress syndrome (RDS) recommend continuous positive airway pressure (CPAP) stabilization as primary treatment. Some surfactant replacement for babies requiring FiO 2 > 0.3 regardless of gestational age (GA). We explore the accuracy alternative inspired oxygen fraction (FiO ) thresholds early predictors in stratified by GA. Study Design Pragmatic, observational study 12 Italian and Spanish intensive care units....

10.1002/ppul.26957 article EN Pediatric Pulmonology 2024-03-13

Blázquez-Gamero, Daniel PhD, MD; Soriano-Ramos, María Martínez de Aragón, Ana Baquero-Artigao, Fernando Frick, Marie Antoinette Noguera-Julian, Antoni Alonso-Ojembarrena, Almudena Moliner Calderón, Elisenda Rives Ferreiro, Teresa Filgueira Posse, Garrote Llanos, Elisa Sota Busselo, Itziar Santos, Mar Tagarro García, Alfredo Bustamante, Jorge Soler-Palacín, Pere Fortuny Guasch, Claudia Rojo Conejo, Pablo and the Spanish Registry of Infants with Congenital Cytomegalovirus Infection (REDICCMV)...

10.1097/inf.0000000000002455 article ES The Pediatric Infectious Disease Journal 2019-10-17

Pneumothorax (PTX) represents accumulation of the air in pleural space. A large or tension pneumothorax can collapse lung and cause hemodynamic compromise, a life-threatening disorder. Traditionally, neonatal diagnosis has been based on clinical images, auscultation, transillumination, chest X-ray findings. This approach may potentially lead to delay both treatment. The use US PTX together with US-guided thoracentesis results earlier more precise management. recommendations presented this...

10.3791/60836 article EN Journal of Visualized Experiments 2020-03-12

Abstract Objective To describe if weekly determined lung ultrasound (LU) scores in preterm infants born before 32 weeks (PTB32W) change with diuretic therapy. Design We included who received diuretics and compared LU according to their evolution on respiratory support (RS) after diuretics. Results 18 PTB32W divided into two groups. Both groups were similar terms of median gestational age: 26 (interquartile range [IQR]: 25–28) the responders' group 27 (IQR: 24–28) other. They differed,...

10.1002/ppul.25098 article EN Pediatric Pulmonology 2020-09-28

<b><i>Introduction:</i></b> Early targeted surfactant therapy for preterm infants is recommended but the best criteria to personalize treatment are unclear. We validate a previously published multivariate prognostic model based on gestational age (GA), lung ultrasound score (LUS), and oxygen saturation inspire fraction ratio (SatO<sub>2</sub>/FiO<sub>2</sub>) using an independent data set. <b><i>Methods:</i></b>...

10.1159/000532083 article EN Neonatology 2023-10-26

The retina functions as a neurovascular unit. How early vascular alterations affect neuronal layers remains controversial; failure could lead to edema increasing retinal thicknesses, but alternatively loss reduced thickness. Objective . To evaluate thickness in cohort of pediatric patients with type 1 diabetes mellitus (PwT1DM) and analyze differences according the presence or absence nonproliferative diabetic retinopathy (NPDR), poor metabolic control, duration. Patients Methods We...

10.1155/2018/1078531 article EN cc-by International Journal of Endocrinology 2018-01-01

Pneumothorax (PTX) represents accumulation of the air in pleural space. A large or tension pneumothorax can collapse lung and cause hemodynamic compromise, a life-threatening disorder. Traditionally, neonatal diagnosis has been based on clinical images, auscultation, transillumination, chest X-ray findings. This approach may potentially lead to delay both treatment. The use US PTX together with US-guided thoracentesis results earlier more precise management. recommendations presented this...

10.3791/60836-v article EN Journal of Visualized Experiments 2020-03-12

Abstract Background In lung ultrasound (LUS), the pleural line is an artifact whose thickness depends on underlying pathology. To date there are no published studies normal values of (PLT) in newborns. Objective The aim our study to describe PLT term newborn (TN) and preterm (PTN). Methods We recruited eupneic TN PTN, under 34 weeks gestation, their first 24 hours life. Newborns presenting any respiratory distress since birth were excluded. LUS was performed four areas: upper anterior, lower...

10.1002/ppul.24920 article EN Pediatric Pulmonology 2020-06-23
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