A5101522600- Optical Imaging and Spectroscopy Techniques
- EEG and Brain-Computer Interfaces
- Attention Deficit Hyperactivity Disorder
- Heart Rate Variability and Autonomic Control
- Neuroinflammation and Neurodegeneration Mechanisms
- Functional Brain Connectivity Studies
- Non-Invasive Vital Sign Monitoring
- Stress Responses and Cortisol
- Alzheimer's disease research and treatments
- Tryptophan and brain disorders
- Barrier Structure and Function Studies
- Inflammasome and immune disorders
- Telomeres, Telomerase, and Senescence
- Genetics, Aging, and Longevity in Model Organisms
- Neural dynamics and brain function
- Religion, Spirituality, and Psychology
- Power System Reliability and Maintenance
- Gait Recognition and Analysis
- Islanding Detection in Power Systems
- Phytochemicals and Antioxidant Activities
- HVDC Systems and Fault Protection
- Immune Cell Function and Interaction
- Fungal Biology and Applications
- Bioactive Compounds in Plants
- Educational Reforms and Innovations
Harvard University
2020-2024
China Power Engineering Consulting Group (China)
2024
Massachusetts General Hospital
2020-2024
First Affiliated Hospital of Zhengzhou University
2024
Hainan University
2024
Tianjin University of Technology
2010-2023
Nantong University
2020-2022
Tsinghua–Berkeley Shenzhen Institute
2021
Henan Provincial People's Hospital
2021
Zhengzhou University
2021
The electroencephalogram (EEG) can reflect brain activity and contains abundant information of different anesthetic states the brain. It has been widely used for monitoring depth anesthesia (DoA). In this study, we propose a method that combines multiple EEG-based features with artificial neural network (ANN) to assess DoA. Multiple express more comprehensively during anesthesia. First, four parameters including permutation entropy, 95% spectral edge frequency, BetaRatio SynchFastSlow were...
Abstract Aims Ischemic stroke is a life‐threatening disease with limited therapeutic strategies. Blood‐brain barrier (BBB) disruption critical pathological process that contributes to poor outcomes in ischemic stroke. We previously showed the microglial inhibition of inflammasome sensor absent melanoma 2 (AIM2) suppressed inflammatory response and protected against However, whether AIM2 involved BBB during cerebral ischemia unknown. Methods Middle artery occlusion (MCAO) oxygen‐glucose...
Abstract Attention-deficit/hyperactivity disorder (ADHD) is a prevalent neurodevelopmental in children. Neuroimaging studies have revealed abnormalities of neural activities some brain regions, including the frontal cortex, striatum, cerebellum, and occipital cortex. Recently, investigators demonstrated that nonlinear complexity analysis activity may provide new index to indicate ADHD. In present study, we used permutation entropy (PE) measure functional near-infrared spectroscopy (fNIRS)...
Objective: Attention-deficit/hyperactivity disorder (ADHD) is one of the most common neuropsychiatric disorders in children and affects 3% to 5% school-aged children. This study demonstrate whether functional near-infrared spectroscopy (fNIRS) can detect changes concentration oxygenated hemoglobin(oxy-HB) with ADHD typically developing children(TD children). Method: In this study, 14 15 TD were studied. Metabolic signals blood oxygen recorded by using fNIRS during go/no-go task. A statistic...
Objective. Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental affecting children and adults. Previous studies found that functional near-infrared spectroscopy (fNIRS) can reveal significant group differences in several brain regions between ADHD healthy controls during working memory tasks. This study aimed to use fNIRS activation patterns identify from controls. Approach. FNIRS signals 25 performing the n-back task were recorded; then, multivariate pattern analysis was...
Functional near-infrared spectroscopy (fNIRS) is a promising technique for monitoring brain activity. However, it sensitive to motion artifacts. Many methods have been developed correction, such as spline interpolation, wavelet filtering, and kurtosis-based filtering. We propose correction method based on empirical mode decomposition (EMD), which applied segments of data identified having The EMD adaptive, data-driven, well suited nonstationary data. To test the performance proposed compare...
Dysfunction of synaptic plasticity leads to memory impairment in Alzheimer's disease (AD). Muscone (Mus) has shown neuroprotective effects cerebral ischemic models. However, little is known Mus on AD.To investigate the functions and 6-month-old APP/PS1 double-transgenic mice explore potential mechanisms.Mus was intraperitoneally injected into or wild-type mice, cognitive function assessed by Novel object recognition Morris water maze tests. The levels amyloid-β (Aβ) were evaluated...
Abstract Objective . Electroencephalogram (EEG) signals suffer inevitable interference from artifacts during the acquisition process. These make analysis and interpretation of EEG data difficult. A major source in EEGs is ocular activity. Therefore, it important to remove before further processing data. Approach In this study, an automatic artifact removal (AOAR) method for proposed based on non-negative matrix factorization (NMF) empirical mode decomposition (EMD). First, amplitude was...
The mitogen-activated protein kinase (MAPK) signaling pathway plays an important role in the regulation of cell growth, proliferation, differentiation, transformation and death. Mitogen-activated phosphatase 1 (MKP1) has inhibitory effect on p38MAPK JNK pathways, but it is unknown whether a Aβ-induced oxidative stress neuronal inflammation. In this study, PC12 cells were infected with MKP1 shRNA, lentivirus or control for 12 hours, then treated 0.1, 1, 10 100 μM amyloid beta 42 (Aβ42)....
Monitoring the changes of cerebral hemodynamics and state consciousness during general anesthesia (GA) is clinically important. There a great need for developing advanced detectors to investigate physiological processes brain GA. We developed multichanneled, functional near-infrared spectroscopy (fNIRS) system device applied it GA operation monitoring. The hemodynamic data from forehead 11 patients undergoing propofol sevoflurane were analyzed. concentration oxygenated hemoglobin,...
The accumulation of insoluble amyloid β (Aβ) peptides is one the pathological changes in Alzheimer's disease (AD), which induced synaptic plasticity impairment and excitatory amino acid toxicity associated with decreased memory function. Xingnaojing (XNJ), a well-known prescription traditional Chinese medicine, has been used for treatment stroke many years China. In this study, we aim to investigate therapeutic effects XNJ hippocampus Aβ1-42 mouse model AD showed significant loss impaired...
Smart grid becomes the hot topic concerning future power development trend home and abroad in recent years. In this paper background, concept, major characteristics, core technologies are described. According to key of smart grid, which include a strong flexible network topology, integrated communication system, fast simulation modeling, advanced metering infrastructure, demand side management, distributed generation integration, distribution automation electronic equipments, research is...
Introduction We examined whether abuse in childhood and/or adolescence was associated with shorter telomere length a pooled analysis of 3,232 participants from five diverse cohorts. also assessed religion or spirituality (R/S) could buffer deleterious effects abuse. Methods Physical and sexual (age <12) 12–18) using the Revised Conflict Tactics Scale questions 1995 Gallup survey. measured relative leukocyte lengths (RTL) quantitative real time polymerase chain reaction. used generalized...