A5014967527- Mosquito-borne diseases and control
- Viral Infections and Vectors
- COVID-19 epidemiological studies
- Virology and Viral Diseases
- Global Maternal and Child Health
- Systemic Sclerosis and Related Diseases
- Health, Nursing, Elderly Care
- Viral gastroenteritis research and epidemiology
- Hip and Femur Fractures
- Plant Virus Research Studies
- Vibrio bacteria research studies
- Neonatal and Maternal Infections
- Healthcare Systems and Public Health
- Malaria Research and Control
- Trypanosoma species research and implications
- SARS-CoV-2 and COVID-19 Research
- Zoonotic diseases and public health
- Cardiac, Anesthesia and Surgical Outcomes
- Cerebral Palsy and Movement Disorders
- Health Education and Validation
Hospital de São João
2024
Fundação Oswaldo Cruz
2019-2023
Knowledge Integration (United Kingdom)
2022
Prenatal exposure to Zika virus has potential teratogenic effects, with a wide spectrum of clinical presentation referred as congenital syndrome. Data on survival among children syndrome are limited.
There is currently no system to track the emergence of Zika virus (ZIKV) subtypes. We developed a surveillance able retrieve sequence submissions and further classify distinct ZIKV genotypes in world. This approach was detect new occurrence from an African lineage Brazil 2019.
The clinical manifestations of microcephaly/congenital Zika syndrome (microcephaly/CZS) have harmful consequences on the child's health, increasing vulnerability to childhood morbidity and mortality. This study analyzes case fatality rate child-maternal characteristics cases deaths related microcephaly/CZS in Brazil, 2015-2017. Population-based developed by linkage three information systems. We estimate frequencies cases, deaths, according child maternal causes death. Multivariate logistic...
The co-circulation of different arboviruses in the same time and space poses a significant threat to public health given their rapid geographic dispersion serious health, social, economic impact. Therefore, it is crucial have high quality case registration estimate real impact each population. In this work, Vector Autoregressive (VAR) model was developed investigate interrelationships between discarded confirmed cases dengue, chikungunya, Zika Brazil. We used data from Brazilian National...
Children with congenital Zika syndrome (CZS) have severe damage to the peripheral and central nervous system (CNS), greatly increasing risk of death. However, there is no information on sequence underlying, intermediate, immediate, contributing causes deaths among these children. The aims this study are describe events leading death children CZS up 36 months age their probability dying from a given cause, 2015 2018.In population-based study, we linked administrative data live births, deaths,...
Zika virus (ZIKV) became a worldwide public health emergency after its introduction in the Americas. Brazil was implicated as central ZIKV dispersion, however, better understanding of pathways took to arrive and dispersion within country is needed. An updated genome dataset assembled with publicly available data. Bayesian phylogeography methods were applied reconstruct spatiotemporal history Americas more detail inside Brazil. Our analyses reconstructed Brazilian state Pernambuco likely...
Abstract Zika virus was responsible for the microcephaly epidemic in Brazil which began October 2015 and brought great challenges to scientific community health professionals terms of diagnosis classification. Due difficulties correctly identifying cases, it is necessary develop an automatic procedure classify probability a CZS case from clinical data. This work presents machine learning algorithm capable achieving this structured unstructured available The proposed reached 83% accuracy with...
This study aims to describe clinical findings and determine the medium-term survival of congenital zika syndrome (CZS) suspected cases.A retrospective cohort using routine register-based linked data. It included all cases CZS born in Brazil from January 1, 2015, December 31, 2018, followed up birth until death, 36 months, or whichever came first. Latent class analysis was used cluster unconfirmed into classes with similar combinations anthropometry at birth, imaging findings, maternally...
Since the beginning of SARS-CoV-2 spread in Brazil, few studies have been published analysing variability viral genome. Herein, we described dynamic strains circulating Brazil from May to September 2020, better understand changes that may affect ongoing pandemic. Our data demonstrate some mutations identified are currently observed variants interest and concern, emphasize importance studying previous periods order comprehend emergence new variants. From 720 genome sequences, found sites...
<h3>Background:</h3> The relationship between manometric changes and esophageal dilation on high-resolution computed tomography (HRCT) is well established in Systemic Sclerosis (SSc),<sup>[1]</sup> but its association with extra-esophageal manifestations inconsistent<sup>[2,3]</sup>. <h3>Objectives:</h3> This study aims to characterize findings SSc patients determine predictive factors of body involvement. <h3>Methods:</h3> a retrospective single-center including adult registered Reuma.pt...
A simulação clínica é uma abordagem pedagógica ativa que proporciona ao discente a oportunidade de tomar decisões por meio cenários realísticos, integrando o conhecimento teórico à prática em um ambiente controlado. É ferramenta ensino objetiva minimizar riscos e exposição do paciente no processo aprendizagem. Objetivos: Identificar os eventuais benefícios da implementação metodologia para formação discentes fisioterapia. Metodologia: Estudo transversal avaliou impactos dos curso...
Abstract The co-circulation of different arboviruses in the same time and space poses a significant threat to public health given their rapid geographic dispersion serious health, social, economic impact. Therefore, it is crucial have high quality case registration estimate real impact each population. In this work, Vector Autoregressive (VAR) model was developed investigate interrelationships between discarded confirmed cases dengue, chikungunya, Zika Brazil. We used data from Brazilian...
Abstract The co-circulation of different arboviruses in the same time and space poses a significant threat to public health given their rapid geographic dispersion serious health, social, economic impact. Therefore, it is crucial have high quality case registration estimate real impact each population. In this work, Vector Autoregressive (VAR) model was developed investigate interrelationships between discarded confirmed cases dengue, chikungunya, Zika Brazil. We used data from Brazilian...
<h3>Background</h3> Hip fractures are the most serious outcome of osteoporosis and a leading public health concern due to associated increase in morbidity mortality, loss independence financial burden. <h3>Objectives</h3> The aim this study was investigate possible predictive factors 1 year mortality patients with fragility proximal femur fracture referred liaison service (FLS). <h3>Methods</h3> Patients aged ≥65 years admitted Orthopaedics department hip were evaluated Rheumatology...