A5062295061- Nanoparticle-Based Drug Delivery
- European Political History Analysis
- Nanoplatforms for cancer theranostics
- Multiculturalism, Politics, Migration, Gender
- Gold and Silver Nanoparticles Synthesis and Applications
- Advanced Nanomaterials in Catalysis
- Healthcare Systems and Practices
- International Law and Aviation
- Historical Studies and Socio-cultural Analysis
- Legal and Social Philosophy
- Dendrimers and Hyperbranched Polymers
- Education, sociology, and vocational training
- Bone Tissue Engineering Materials
- Political and Social Issues
- Nanocluster Synthesis and Applications
- Global Politics and Economy
- American Constitutional Law and Politics
- Health, Medicine and Society
- Social Sciences and Governance
- Catalytic Processes in Materials Science
- Radiation Therapy and Dosimetry
- X-ray Diffraction in Crystallography
- Nanoparticles: synthesis and applications
- TiO2 Photocatalysis and Solar Cells
- Catalytic Cross-Coupling Reactions
Centre National de la Recherche Scientifique
2009-2024
Laboratoire Interdisciplinaire Carnot de Bourgogne
2012-2024
Université Bourgogne Franche-Comté
2016-2024
Université Paris-Saclay
2023
Centre de Recherches Sociologiques sur le Droit et les Institutions Pénales
2022
Maison des Sciences de l’Homme de Dijon
2014-2021
Université de Bourgogne
2005-2021
Université de Reims Champagne-Ardenne
2009-2020
Institut de Chimie de la Matière Condensée de Bordeaux
2015
Université Paris-Panthéon-Assas
2000-2014
The quest for small molecules that strongly bind to G-quadruplex-DNA (G4), so-called G4 ligands, has invigorated the research field from its very inception. Massive efforts have been invested discover or rationally design evaluate their G4-interacting properties in vitro through a series of now widely accepted and routinely implemented assays, use them as innovative chemical biology tools interrogate cellular networks might involve G4s. In sharp contrast, only uncoordinated aimed at...
Superparamagnetic iron oxide nanoparticles were developed as positron emission tomography (PET) and magnetic resonance imaging (MRI) bimodal agents. These (NPs), with a specific nanoflower morphology, first synthesized simultaneously functionalized 3,4-dihydroxy-l-phenylalanine (LDOPA) under continuous hydrothermal conditions. The resulting NPs exhibited low hydrodynamic size of 90 ± 2 nm. functional groups LDOPA (-NH2 -COOH) successfully used for the grafting molecules interest in second...
Copper-doped zinc oxide nanoparticles (NPs) CuxZn1−xO (x = 0, 0.01, 0.02, 0.03, and 0.04) were synthesized via a sol-gel process used as an active electrode material to fabricate non-enzymatic electrochemical sensor for the detection of glucose. Their structure, composition, chemical properties characterized using X-ray diffraction (XRD), transmission electron microscopy (TEM), Fourier-transform infrared (FTIR) Raman spectroscopies, zeta potential measurements. The characterization sensors...
Ligand exchange on [Au25(SCH2CH2Ph)18−] [TOA+] is studied with two chiral ligands R/S-BINAS and NILC/NIDC in THF induction of metal-based optical activity. Under the applied condition ligand only partial, showing that also within a mixed shell significant activity can be induced. The resulted change particle size as observed by UV−vis spectroscopy.
In the present study, we report dispersion of titanate nanotubes (TiONts) via polymer grafting (PolyEthylene Glycol, PEG) or adsorption (polyethylene imine, PEI) where different TiONts/polymer ratios have been investigated. The TiONts/PEI and TiONts/PEG nanohybrids were characterized by scanning transmission electron microscopy as well zeta potential measurements in order to determine both their state stability water (at pH for zetametry). nature chemical bonds at surface these was...
Nanohybrids based on titanate nanotubes (TiONts) were developed to fight prostate cancer by intratumoral (IT) injection, and particular attention was paid their step-by-step synthesis. TiONts synthesized a hydrothermal process. To develop the customengineered nanohybrids, surface of coated beforehand with siloxane (APTES), coupled both dithiolated diethylenetriaminepentaacetic acidmodified gold nanoparticles (Au@DTDTPA NPs) heterobifunctional polymer (PEG3000) significantly improve...
Abstract Liquid‐crystalline dendrons carrying either a thiol or disulfide function which display nematic, smectic A, columnar, chiral nematic phases have been synthesized. Their mesomorphic properties are in agreement with the nature of mesogenic units and structure dendrons. The first‐generation poly(aryl ester) dendron containing two cyanobiphenyl was used to functionalize gold nanoparticles. For full coverage, smectic‐like supramolecular organization on nanometer scale is observed, when...
For the first time, phosphonate-functionalized magnetite nanoparticles (Fe3O4 NPs) were synthesized using a one-step continuous hydrothermal process. The NP surface was modified hydrophilic organic molecule, namely 6-phosphonohexanoic acid (PHA). NPs fully characterized (TEM, XRD, DLS, ζ-potential, TGA, FTIR, XPS and specific area measurements) in order to investigate PHA effect on size, oxidation state, anchoring colloidal stability. reduced crystallite size distribution improved greatly...
In this work, new nanohybrids based on superparamagnetic iron oxide nanoparticles (SPIONs) were elaborated and discussed for the first time as nanovectors of a derivative molecule trans-resveratrol (RSV), natural antioxidant molecule, which can be useful brain disease treatment. The was chemically synthesized (4’-hydroxy-4-(3-aminopropoxy) trans-stilbene: HAPtS) then grafted onto SPIONs surface using an organosilane coupling agent, is 3-chloropropyltriethoxysilane (CPTES) nucleophilic...
Abstract Herein we report the studies of Heck alkynylation (copper‐free Sonogashira) with aryl halides (I, Br, Cl) employing various metallic precursors, tertiary phosphanes and bases in [BMIM][BF 4 ] as solvent. As a result, provide first method that allows coupling large array substrates, either activated or deactivated bromides an ionic liquid. Furthermore, system highest efficiency is unexpectedly simplest cheaper combination employs [Pd(η 3 ‐C H 5 )Cl] 2 /PPh at only 1 mol‐% loading...
In this work, we discuss for the first time elaboration of nanohybrid materials, intended drug delivery systems, based on titanate nanotubes (TiONts) coated with chitosan polymer (CT). Chitosan has been used to enhance biocompatibility hydrothermally synthesized in biological medium as a substitute polyethylene glycol (PEG) that is generally biocompatibility. CT grafting was carried out using two different approaches; made by covalent bond intermediate molecules, and second electrostatic...
The combination of anticancer drugs and metal oxide nanoparticles is great interest in cancer nanomedicine. Here, the development a new nanohybrid, titanate nanotube-docetaxel (TiONts-DTX) reported, two parts which are conjugated by covalent linkages. Unlike most currently being developed for biomedical purposes, TiONts present needle-shaped morphology. surface linked with 3-aminopropyl triethoxysilane hetero-bifunctional polymer (polyethylene glycol) to create well-dispersed biocompatible...
Abstract: Around 40% of high-risk prostate cancer patients who undergo radiotherapy (RT) will experience biochemical failure. Chemotherapy, such as docetaxel (DTX), can enhance the efficacy RT. Multidrug resistance mechanisms often limit drug by decreasing intracellular concentrations drugs in tumor cells. It is, therefore, interest to develop nanocarriers DTX maintain inside cells and thus improve treatment efficacy. The purpose this study was investigate use titanate nanotubes (TiONts) a...
Introduction. The objective of this study was to evaluate the feasibility and toxicity superparamagnetic iron oxide nanoparticles (SPIONs) administered into cochlea through round window (RW) by an external magnetic field. Materials Methods. In 5 Wistar rats, left RW punctured. SPIONs suspended in hyaluronic gel (5 mg/mL) were applied niche covered a muscle graft. mobilized using rare earth magnet (0.54 T) held 4 consecutive positions around head. right ear served as control. Hearing function...
A combination of in situ attenuated total reflection infrared (ATR-IR) spectroscopy, UV−vis spectroscopy and transmission electron microscopy was used to study the adsorption thiol-protected gold nanoparticles on TiO2 films behavior resulting composite upon UV irradiation. The were covered by charged thiols N-acetyl-l-cysteine l-glutathione had a mean core diameter about 1 nm. film prepared deposition slurry with particles size 21 two spectroscopic techniques showed that onto is...
Metal nanoparticles (NPs) colloids provide a unique combination of optical, magnetic, electronic, and thermal properties, finding applications in various fields ranging from optoelectronics to cancer therapy. The chemical synthesis such NPs has been refined high degree control crystallinity, shape, size distribution. Among them, gold are particular interest because they host plasmonic resonances that enhance their interactions with light. Their shape impose the resonance wavelengths, which,...
Organobismuth compounds have been known for centuries as substances of medical interest, and continue to be used in medicine today.