A5082656332- Air Quality and Health Impacts
- Nanoparticles: synthesis and applications
- Pulmonary Hypertension Research and Treatments
- Neurotransmitter Receptor Influence on Behavior
- Neuroscience and Neuropharmacology Research
- Receptor Mechanisms and Signaling
- Helicobacter pylori-related gastroenterology studies
- Advanced ceramic materials synthesis
- Silicon Nanostructures and Photoluminescence
- Liver Disease Diagnosis and Treatment
- Neural dynamics and brain function
- Plasma Diagnostics and Applications
- Vascular Malformations and Hemangiomas
- Characterization and Applications of Magnetic Nanoparticles
- Asthma and respiratory diseases
- Liver physiology and pathology
- Silicone and Siloxane Chemistry
- Mitochondrial Function and Pathology
- Tissue Engineering and Regenerative Medicine
- Enterobacteriaceae and Cronobacter Research
- Neurofibromatosis and Schwannoma Cases
- COVID-19 Clinical Research Studies
- Nanoparticle-Based Drug Delivery
- Nitric Oxide and Endothelin Effects
- Respiratory viral infections research
Université de Bordeaux
2016-2025
Inserm
2012-2025
Centre National de la Recherche Scientifique
2016-2025
École Nationale Supérieure de Chimie de Montpellier
2024
Université de Montpellier
2024
Institut Charles Gerhardt Montpellier
2024
Bordeaux Imaging Center
2011-2023
Centre de Recherche Cardio-Thoracique de Bordeaux
2022
Bordeaux Population Health
2012-2022
Université Bordeaux Montaigne
2022
Abstract Organic donor–acceptor–donor (D–A–D) polymers or small molecules are widely investigated in organic solar cells due to their broad light absorption, narrow band gap, excellent charge mobility, and exciton seperation at the interface. However, studies of conjugated with D–A–D molecule structures as photocatalytically active materials still rare. In this study, an unprecedented demonstration that photocatalytic activity can fact be affected by tuning D A is given. Especially, EBE...
PEGylated magnetic iron oxide nanoparticles (IONPs) were synthesised with the aim to provide proof of concept results remote cancer cell killing by fluid hyperthermia.
Abstract Dopamine transmission is involved in reward processing and motor control, its impairment plays a central role numerous neurological disorders. Despite strong pathophysiological relevance, the molecular structural organization of dopaminergic synapse remains to be established. Here, we used targeted labelling fluorescence activated sorting purify striatal synaptosomes. We provide proteome synapses with 57 proteins specifically enriched. Beyond canonical markers dopamine...
Helicobacter pylori chronically infects the gastric mucosa in more than half of human population; a subset this population, its presence is associated with development severe disease, such as cancer. Genomic analysis several strains has revealed an extensive H. pan-genome, likely to grow genomes are sampled. Here we describe draft genome sequence (63 contigs; 26× mean coverage) strain B45, isolated from patient mucosa-associated lymphoid tissue (MALT) lymphoma. The major finding was 24.6-kb...
Doping material with nanoparticles is increasingly used as an effective method for improving their mechanical, optical, and sturdiness properties in many fields. More specifically, development will depend on our ability to control nanoparticles' shape, composition, size. While crystalline nanophase can be examined easily, characterization of amorphous remains a challenge. Here, we investigate the chemical composition sub-20-nm oxide grown rare-earth doped silicate glass through phase...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections initiate in the bronchi of upper tract and are able to disseminate lower tract, where can cause an distress with a high degree mortality elderly patients. We used reconstituted primary bronchial epithelia from adult child donors follow SARS-CoV-2 infection dynamics. show that, donors, multiciliated cells spread within 24 48 h throughout whole epithelia. Syncytia formed ciliated basal appeared at apical side 3 4 d were...
Significance Although a role for β-adrenergic receptor (ADRB) in cancer progression was suggested long time ago, our serendipitous observation of the propranolol efficacy treating infantile hemangioma (IH) has driven attention exploring antitumor properties β-blockers. We identified Aquaporine-1 (AQP1) as player response and histological marker IH vascular structures including telocytes, which are dendritic cells that form distinctive peripheral layer IH. conclude sensitivity to may rely, at...
The morphology and surface chemistry of silica particles can be easily tuned via the co-condensation organo-alkoxides with TEOS. Surface charge, particle density, size distribution were all dependent on precursor combination used.
Liver sinusoidal endothelial cells (LSECs) possess fenestrae, which are key for the exchange between blood and hepatocytes. Alterations in their number or diameter have important implications hepatic function liver diseases. They lost early development of fibrosis through a process called capillarization. In this study, we aimed to demonstrate whether vitro dedifferentiated LSECs that fenestrae able re‐form these structures. Using stimulated emission depletion super‐resolution microscopy...
Alterations in lipid handling are an important hallmark cancer. Our aim here is to target key metabolic enzymes reshape the oncogenic metabolism triggering irreversible cell breakdown. We targeted player proprotein convertase subtilisin/kexin type 9 (PCSK9) using a pharmacological inhibitor (R-IMPP) alone or combination with 3-hydroxy 3-methylglutaryl-Coenzyme A reductase (HMGCR) inhibitor, simvastatin. assessed effect of these treatments 3 hepatoma lines, Huh6, Huh7 and HepG2 tumor...
A goal in the field of nanoscale optics is fabrication nanostructures with strong directional light scattering at visible frequencies. Here, synthesis Mie-resonant core-shell particles overlapping electric and magnetic dipole resonances spectrum demonstrated. The core consists silicon surrounded by a lower index oxynitride (SiOxNy) shell an adjustable thickness. Optical spectroscopies coupled to Mie theory calculations give first experimental evidence that relative position intensity are...
In New Caledonia, anthropic activities, such as mining, increase the natural erosion of soils in nickel mines, which turn, releases oxide nanoparticles (NiONPs) into atmosphere. Pulmonary vascular endothelial cells represent one primary targets for inhaled nanoparticles. The objective this vitro study was to assess cytotoxic effects NiONPs on human pulmonary artery (HPAEC). Special attention will be given level oxidative stress and calcium signaling, are involved physiopathology...
BackgroundPatients with severe asthma show an increase in both exacerbation frequency and bronchial smooth muscle (BSM) mass. Rhinovirus (RV) infection of the epithelium (BE) is main trigger exacerbations. Histological analysis biopsies shows that a close connection between BE hypertrophic BSM criterion for severity asthma.ObjectiveWe hypothesized RV specifically increases BSM-cell migration from patients asthma.MethodsSerum samples, biopsies, or cells were obtained 86 31 subjects without...
A new liquid-phase redox synthesis to form silicon nanoparticles allows the solvent used during determine particle size and fluorescent properties.
Because synthetic vascular prostheses perform poorly in small-diameter revascularization, biological substitutes are being developed as an alternative. Although theirin vivoresults promising, their production involves long, complex, and expensive tissue engineering methods. To overcome these limitations, we propose innovative approach that combines the human amniotic membrane (HAM), which is a widely available cost-effective raw material, with rapid robust textile-inspired assembly strategy....