A5032274128- Breast Cancer Treatment Studies
- Health Systems, Economic Evaluations, Quality of Life
- Frailty in Older Adults
- Esophageal Cancer Research and Treatment
- HER2/EGFR in Cancer Research
- Economic and Financial Impacts of Cancer
- Nutrition and Health in Aging
- Global Cancer Incidence and Screening
- Calcium signaling and nucleotide metabolism
- Pharmaceutical Economics and Policy
- Advanced Breast Cancer Therapies
- Pharmacogenetics and Drug Metabolism
- PARP inhibition in cancer therapy
- Drug-Induced Adverse Reactions
- Monoclonal and Polyclonal Antibodies Research
- Cancer Treatment and Pharmacology
- Sirtuins and Resveratrol in Medicine
- Pharmaceutical studies and practices
- Drug Transport and Resistance Mechanisms
University of Hong Kong
2013-2022
Niagara Health System
2020
Kwai Chung Hospital
2020
Chinese University of Hong Kong
2013
In this study, we report the identification of a novel role SIRT6 in both epirubicin and paclitaxel resistance breast cancer. We found that protein levels are elevated paclitaxel- epirubicin-resistant MCF-7 cells compared with parental sensitive cells. knockout depletion sensitized to treatment, whereas ectopic overexpression led increased epirubicin. Moreover, our data suggest could be mediating through enhancing DNA repair response epirubicin-induced damage. Clonogenic assays also revealed...
TPS599 Background: Multi-parameter tumor gene expression assays (MPAs) are validated tools to assist adjuvant chemotherapy decisions for post-menopausal women with luminal-type node-negative breast cancer. Currently there is less certainty 1-3 involved axillary lymph nodes and no information on MPA use patients higher level nodal involvement. Three RCTs available data report benefit premenopausal women; limited of ovarian function suppression (OFS) non-chemotherapy treated participants,...
Breast cancer (BC) treatment has shifted from chemotherapy to targeted therapy. Several agents have demonstrated an improvement in survival. Given that national healthcare resources were correlated with the mortality-to-incidence ratio, we compared access BC drugs Thailand other Asian countries.BC experts involved International Group (BIG)-Asia six representative groups for countries or special administrative region (SAR) Asia (Hong Kong SAR, Japan, Korea, Taiwan, Thailand, and Singapore)...
Following the inception in 2010, University of Nottingham hosted 4th Symposium on Primary Breast Cancer Older Women, under auspices International Society Geriatric Oncology, March 2017, at East Midlands Conference Centre. This is only meeting its kind UK, now held biennially, aiming a multidisciplinary audience, including patients, their carers and advocates. With theme 'Putting personalising care into practice', this included sessions 'local systemic therapies', 'new ideas', 'patients...