A5081610918- Antibiotics Pharmacokinetics and Efficacy
- SARS-CoV-2 and COVID-19 Research
- SARS-CoV-2 detection and testing
- Synthesis and Biological Evaluation
- Animal Virus Infections Studies
- Pharmaceutical and Antibiotic Environmental Impacts
- Viral gastroenteritis research and epidemiology
- Vibrio bacteria research studies
- CRISPR and Genetic Engineering
- Bacteriophages and microbial interactions
- Vector-Borne Animal Diseases
- Virology and Viral Diseases
- Advanced biosensing and bioanalysis techniques
- COVID-19 Clinical Research Studies
- Biosensors and Analytical Detection
- Salmonella and Campylobacter epidemiology
- Antibiotic Resistance in Bacteria
- Animal Disease Management and Epidemiology
- Veterinary medicine and infectious diseases
- Reproductive Physiology in Livestock
- COVID-19 diagnosis using AI
- Pesticide Residue Analysis and Safety
- Probiotics and Fermented Foods
- Gut microbiota and health
- Synthesis and Reactions of Organic Compounds
Karachi Medical and Dental College
2025
University of Veterinary and Animal Sciences
2011-2024
Kinnaird College for Women University
2024
Huazhong Agricultural University
2016-2020
Abstract Coccidiosis causes huge economic losses worldwide. Current study evaluated the effect of biosynthesized Zinc oxide nanoparticles (ZnONPs) using Nigella sativa, on Eimeria tenella infected broilers. Scanning electron microscopy showed spherical ZnONPs with 50–100 nm diameter, Fourier transforms infrared spectroscopy revealed functional groups involved in reduction zinc acetate dihydrate to ZnONPs, UV–vis a peak at 354 nm, and Zeta potential exhibited stability − 30 mV. A total 150,...
Guar gum, extracted from the seeds of Cyamopsis tetragonolobus, has gained prominence for its unique properties, forming a thick gel in water and releasing fatty acids through fermentation. Originating Pakistan India, it found industrial significance US during 1940s. The galactomannan guar's endosperm, polysaccharide d-mannose d-galactose, imparts rapid solubility, pH stability, biodegradability. Beyond applications, guar gum exhibits myriad health benefits. Delving into botanical symphony...
Fluoroquinolones (FQs) are important antibiotics used for treatment of Salmonella infection in poultry many countries. However, oral administration fluoroquinolones may affect the composition and abundance a number bacterial taxa chicken intestine. Using 16S rRNA gene sequencing, microbial shifts gut infected chickens response to enrofloxacin treatments at different dosages (0, 0.1, 4 100 mg/kg b.w.) were quantitatively evaluated. The results showed that shedding levels significantly reduced...
I am writing this letter to address an increasingly high-risk but under-explored complication of pituitary apoplexy in patients who have contracted COVID-19. In light recent research, we are beginning understand the magnitude effects that COVID-19 virus has had on human body; one those is brain, particularly gland, which more prone after infection. Pituitary a rare severe condition characterised by sudden haemorrhage or infarction gland. Recent studies highlighted potential link between...
Newcastle disease (ND) is one of the most deadly diseases poultry around globe. The endemic in Pakistan and recurrent outbreaks are being reported regularly wild captive, rural commercial flocks. Though, efforts have been made to characterize causative agent some parts country, genetic nature strains circulating throughout currently lacking. To ascertain genetics NDV, 452 blood samples were collected from 113 flocks, originating all provinces Pakistan, showing high mortality (30–80%)....
The poor palatability, variable oral bioavailability, stimulation to gastric mucosa, and light instability limited the application of enrofloxacin (ENR). enteric granules combining solid lipid nanoparticles (SLNs) with coating were explored overcome these disadvantages.ENR-loaded SLNs produced by a hot homogenization ultrasonic emulsification method as inner core prepared wet granulation followed using polyacrylic resin II (PRII). formulation was optimized orthogonal or single factor test...
Commercial poultry is an important agricultural industry worldwide. Although dense living conditions and large flocks increase meat egg production, they also the risk of disease outbreaks zoonoses. Current pathogen identification methods mostly rely on culture-dependent techniques and, therefore, are limited to a very small number bacteria present in environment. Next Generation Sequencing allows for culture-independent characterization lower respiratory microbiome birds including novel...
Campylobacter jejuni is considered as the leading cause of gastroenteritis all over world. This bacterium has CRISPR–cas9 system, which used a gene editing technique in different organisms. However, its role bacterial virulence just been discovered; that discovery, however, tip iceberg. The purpose this study to find out relationship between cas9 and both phenotypically genotypically C. NCTC11168. Understanding aspects allows for much deeper understanding mechanism pathogenesis. present...
A broad-spectrum microbiological inhibition method has been developed for rapidly screening different kinds of antibiotics such as β-lactam, aminoglycosides, tetracyclines, sulfonamides, macrolides, lincosamides and quinolones in milk, chicken egg honey by using an easy sample preparation. The system microtiter plates consists agar medium, a mixture nutrients, test bacteria (Geobacillus stearothermophilus var C953), bromocresol purple, other supplements trimethoprim, chloramphenicol,...
Several factors are involved in the emergence of antibiotic-resistant bacteria and pose a serious threat to public health safety. Among them, clustered regularly interspaced short palindromic repeat- (CRISPR-) Cas system, an adaptive immune is thought be development antibiotic resistance bacteria. The current study was aimed at determining not only presence CRISPR-Cas system but also their association with each other
A multidisciplinary, collaborative project was conducted to determine the prevalence and distribution of soil-borne zoonotic pathogens in Lahore district Pakistan ascertain its Public Health Significance. Using a grid-based sampling strategy, soil samples (n = 145) were collected from villages 29, 5 samples/village) examined for Bacillus anthracis, Burkholderia mallei/pseudomallei, Coxiella burnetii, Francisella tularensis, Yersinia pestis using real time PCR assays. Chemical analysis also...
To investigate the optimal dosage which can improve clinical efficacy and minimize resistance, pharmacokinetics/pharmacodynamics model of enrofloxacin was established. Effect treatments on clearance Salmonella in experimentally infected chickens simultaneously resistance selection coliforms were evaluated three treatment groups (100, PK/PD designed 4, 0.1 mg/kg b.w.) a control group. Treatment duration rounds 7-day alternated with withdrawal. Results showed that 100 b.w. completely...
ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections has affected more than 15 million people and, as of 22 July 2019, caused deaths 0.6 individuals globally. With the excretion SARS-CoV-2 in stool symptomatic and asymptomatic COVID-19 patients, its genome detection sewage water can be used a powerful epidemiological tool to predict number positive cases population. This study was conducted detect during lockdown. Sewage samples, from 28 pre-selected sites, were...
Toxoplasmosis is a globally distributed disease of warm-blooded animals. It caused by the opportunistic parasite Toxoplasma gondii (T. gondii). One-third global human population believed to be infected with T. gondii. Cats serve as final host and are main source contamination soil water. This study aimed detect genotypes in cats. Fecal samples (n = 400) were collected from districts South Punjab (Khanewal Sahiwal), processed polymerase chain reaction (PCR) followed sequencing phylogenetic...
We report the complete genome sequence of avian paramyxovirus 1 (APMV-1) isolated from an acute and highly contagious outbreak in pheasants (Pucrasia macrolopha) Lahore, Pakistan. Biological serological characterization showed a velogenic strain APMV-1, which was further confirmed by analysis cleavage site fusion protein. Complete sequencing phylogenetic indicated that this isolate belonged to genotype VII, specifically subgenotype VIIa, clustered closely with isolates characterized...