Youyou Lü

ORCID: 0000-0002-2639-0604
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About
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Research Areas
  • Infant Nutrition and Health
  • Gut microbiota and health
  • Probiotics and Fermented Foods
  • Gastrointestinal motility and disorders
  • Proteins in Food Systems
  • Food Allergy and Anaphylaxis Research
  • Microbial Metabolites in Food Biotechnology
  • Biosensors and Analytical Detection
  • Digestive system and related health
  • Food Quality and Safety Studies
  • Bacteriophages and microbial interactions
  • Advanced biosensing and bioanalysis techniques
  • Protein Hydrolysis and Bioactive Peptides
  • Transgenic Plants and Applications
  • Biochemical Analysis and Sensing Techniques
  • Microbial Metabolism and Applications
  • Meat and Animal Product Quality
  • Allergic Rhinitis and Sensitization
  • Asthma and respiratory diseases
  • Diet and metabolism studies
  • Polysaccharides Composition and Applications
  • Bioactive Compounds in Plants
  • Diet, Metabolism, and Disease
  • Insect Utilization and Effects
  • Melamine detection and toxicity

Huazhong Agricultural University
2022-2024

Ocean University of China
2019-2024

Institute of Food Science & Technology
2022

Northwest A&F University
2017

In this study, the effectors and mechanisms of Bifidobacterium bifidum FL-276.1 B. FL-228.1 in alleviating dextran sulfate sodium (DSS)-induced colitis were investigated. Both significantly alleviated DSS-induced colitis, whether they supplemented from beginning experiment (whole course intervention) or after DSS induction started (partial intervention). Aryl hydrocarbon receptor (AHR) nuclear factor erythroid 2-related 2 (NRF2) pathways activated mice colons, while NLR family pyrin domain...

10.1021/acs.jafc.2c06894 article EN Journal of Agricultural and Food Chemistry 2023-01-12

Four typical dietary polyphenols ((−)-epigallocatechin gallate (EGCG), quinic acid (QA), caffeic (CA), and ferulic (FA)) were covalently prepared with rice recombinant human lactoferrin (OsrhLF) bovine (bLF), their structure physicochemical properties investigated, different lycopene emulsions made by ultrasonic emulsification to analyze gastrointestinal fate. The results indicated that the covalent modification changed secondary/tertiary of LF, significantly improving surface...

10.1021/acs.jafc.3c06856 article EN Journal of Agricultural and Food Chemistry 2024-01-23

<italic>Bifidobacterium animalis</italic> subsp. <italic>Lactis</italic> F1-7 (F1-7) could alleviate hyperlipidemia through LXR/NPC1L1 pathway and FXR/FGF15/CYP7A1 pathway.

10.1039/d0fo02255a article EN Food & Function 2020-01-01

5-Hydroxytryptamine (5-HT) could play a role in alleviating symptoms constipation. However, the mechanism underlying of intestinal flora promotion 5-HT secretion by enterochromaffin cells (ECs) and regulation gastrointestinal endocrine system remains unclear.A constipation mouse model was constructed, 5-HT, chromogranin A (CGA), substance P (SP), motilin (MTL), dopamine, noradrenaline expression levels were measured using enzyme-linked immunosorbent assay(Elisa) immunofluorescence, key...

10.1111/nmo.14082 article EN Neurogastroenterology & Motility 2021-01-15

<italic>Bifidobacterium animalis</italic> F1-7 in combination with konjac glucomannan promoted the metabolism of tryptophan and short-chain fatty acids, regulated humoral transport improved constipation.

10.1039/d0fo02227f article EN Food & Function 2020-12-10

The retention ability of strains was evaluated by fluorescence labelling and elaborated on intestinal peristalsis-promoting probiotics, using zebrafish as a model.

10.1039/c8fo02523a article EN Food & Function 2019-01-01

The relationship between bacterial strains and serotonin regulation was studied via the in vitro screening of strains. Using transparent visibility zebrafish, for intestinal peristalsis were quickly screened. methods results as follows: (1) 18 with outstanding gastrointestinal viability their surface hydrophobicity, self-aggregation ability, acid tolerance, bile simulated gastric digestion fluid tolerance determined from 54 unpublished (2) 5dpf zebrafish randomly selected divided into 22...

10.1039/c9fo02129a article EN Food & Function 2019-01-01

Nisin is used as a natural food preservative because of its broad-spectrum antimicrobial activity against Gram-positive bacteria. However, free nisin susceptible to various factors that reduce activity. Milk protein, protein derived from milk, has self-assembly properties and good carrier bioactive substances. In this study, lactoferrin–nisin nanoparticles (L-N), bovine serum albumin–nisin (B-N), casein–nisin (C-N) were successfully prepared by technique, then their investigated. The studies...

10.3390/foods13111606 article EN cc-by Foods 2024-05-22

Abstract Background Constipation is a gastrointestinal symptom with high incidence rate and large number of patients. It becoming one the urgent medical problems. Poor intestinal motility important causes constipation. Current drug treatments for constipation are associated many side effects; thus, it necessary to study more effective treatment methods potential mechanism. Methods A zebrafish model obstruction was established by loperamide hydrochloride evaluate effect probiotic, food...

10.1111/nmo.14196 article EN Neurogastroenterology & Motility 2021-08-01

Aquatic food allergy has become a key safety problem and therefore it is urgent to study the mechanism of aquatic allergy. Turbot parvalbumin (PV) major marine allergen that could cause allergic reactions but cellular molecular mechanisms remain be defined. In this study, we used flow cytometry ELISA, coupled co-culture system dendritic cells T cells, revealed PV promote maturation mainly by inducing bone marrow-derived (BMDCs) express MHC II CD86, cytokines/chemokines IL-6, IFN-γ, IL-23,...

10.1039/d1fo04070g article EN Food & Function 2022-01-01

Parvalbumin (PV) is the most common allergen in fish. Some patients with fish allergy are allergic to only one species of but tolerant others; however, underlying mechanism has not been identified. This study showed that three types glycated fishes' PV a similar decrease immunoglobulin E (IgE) binding. Glycosylation could improve simulated gastric fluid (SGF) and intestinal (SIF) digestion resistance PV. We also discovered cross-reactivity between eel turbot was weaker than bass;...

10.1021/acs.jafc.2c04423 article EN Journal of Agricultural and Food Chemistry 2022-08-11
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