A5108002836- Reproductive Biology and Fertility
- Ovarian function and disorders
- Pregnancy and preeclampsia studies
- Gestational Diabetes Research and Management
- Birth, Development, and Health
- Glaucoma and retinal disorders
- Facial Trauma and Fracture Management
- Neonatal Respiratory Health Research
- Cardiac, Anesthesia and Surgical Outcomes
- Growth Hormone and Insulin-like Growth Factors
- Ovarian cancer diagnosis and treatment
- Medical and Biological Sciences
- Neuroscience of respiration and sleep
- Public Procurement and Policy
- Peroxisome Proliferator-Activated Receptors
- Osteoarthritis Treatment and Mechanisms
- Lysosomal Storage Disorders Research
- Pregnancy and Medication Impact
- Cardiac and Coronary Surgery Techniques
- Environmental Justice and Health Disparities
- COVID-19 Impact on Reproduction
- Municipal Solid Waste Management
- Advanced Glycation End Products research
- Genomic variations and chromosomal abnormalities
- Blood transfusion and management
Armed Forces Institute of Pathology
2025
National University of Medical Sciences
2025
National Institute of Cardiovascular Diseases
2024
Aga Khan University
2024
Health Services Academy
2024
Stony Brook School
2023
Stony Brook University
2023
Bahria University
2018-2023
Aintree University Hospital
2020-2022
University of Liverpool
2020-2022
To determine frequency of Low Birth Weight (LBW) at term and to various associated risk factors.This cross-sectional study was conducted in Department Obstetrics Gynaecology Layari General Hospital Dow University Health Sciences Karachi between January 2007 July 2008. Women with singleton pregnancy 37 above completed weeks were identified. Those women who gave birth babies less than 2500gm recruited the study. In all those patients LBW factors assessed. The variables including age, parity,...
Significance Gaucher disease is a rare genetic disorder that has crippling health consequences. Mutations in the GBA1 gene are known to disrupt enzyme glucocerebrosidase-1, but it not known, at atom-level detail, as how function lost. This study uses multiscale simulations and deep learning define precisely mechanism underlying disruption of glucocerebrosidase-1 and, particular, its interaction with facilitator protein, saposin C.
The primitive neurohypophyseal nonapeptide oxytocin (OXT) has established functions in parturition, lactation, appetite, and social behavior. We have shown that OXT direct actions on the mammalian skeleton, stimulating bone formation by osteoblasts modulating genesis function of bone-resorbing osteoclasts. deleted receptors (OXTRs) selectively osteoclasts using Col2.3Cre Acp5Cre mice, respectively. Both male female Col2.3Cre+:Oxtrfl/fl mice recapitulate low-bone mass phenotype Oxtr+/-...
Background: The occurrence of a single beta thalassaemia allele is frequently related with microcytic hypochromic red blood cells and rise in HbA2 levels. In some carriers, the outcome this or its collaboration other acquired genetic defects may result normal borderline Haemoglobin bA2 Objective was to establish importance molecular analysis individuals significance population screening program. Methods: It cross-sectional study conducted over period six months, from July-December 2023. All...
Objective: To compare the intravenous Labetalol versus hydralazine in patients having severe Pregnancy induced hypertension (PIH) and pre eclampsia (PE) pregnancy.Methods: Seventy eight women admitted Department of Gynecology Obstetrics, Civil Hospital Karachi, PIH/PE fulfilling inclusion criteria were included study. Random selection was performed using sealed opaqe envelop for administration either noted (IV) or Hydrallazine. The mean fall MAP each group noted. This data compared by...
Objectives : To determine whether paternal factors i.e., age, tobacco use and genital tract infection increase the risk for spontaneous first trimester miscarriage. Methodology This case control study was conducted in Department of Obstetrics & Gynaecology, Unit V / IV, Dow Medical College Lyari General Hospital, University Health Sciences, Karachi, Pakistan. Duration two half years, from Nov, 2007 to Apr, 2010. Inclusion criteria were pregnant women with age 20 - 35 years irrespective...
Objective: To evaluate the correlation between clinical hyperandrogenism-hirsutism assessed by modified Ferriman-Gallwey (F-G) score, anthropometric, metabolic and endocrine parameters among PCOS infertile women.
 Methods: This observational study after approval of FRC & ERC BUMDC was conducted from September 2018-March 2019. It included seventy women aged 20-40 years who presented in infertility clinic a local Hospital Karachi. After written informed consent participants were...
Polycystic ovarian syndrome (PCOS) is now considered as a complicated disease of endocrine system. It found in 5- 10% women fertile age group. was initially reproductive disorder women. Studies recent past have documented that PCOS metabolic and influenced by genetic environmental factors. also transferred genetically, an autosomal dominant trait with variable penetrance. Since role insulin resistance has been identified main culprit the development therefore use sensitizers to treat seems...
Objective: During pregnancy, sonographic measurements of subcutaneous adipose tissue may be a reliable diagnostic predictor gestational diabetes mellitus (GDM) and fetal metabolism. A view the abdominal circumference can used to measure anterior wall thickness (AAWT), which is straightforward simple. Consequently, in this study, aim was evaluate whether AAWT value could as indicator GDM, thus preventing adverse neonatal maternal outcomes thereof, including shoulder dystocia, hypoxia, injury...
The study aimed to determine the tolerance of Pasundan bull's sperm with different alginate and calcium chloride (CaCl2) concentrations identify optimal conditions for encapsulation. Semen samples were collected weekly artificial vaginas from pasundan bulls. Pooled semen was divided into 9 equal volumes. first sample diluted tris egg yolk extender (control), 4 supplemented (0.25, 0.5, 0.75, 1%), other CaCl2 (2.5, 5, 10, 20 mM). Evaluation determined after 5 min incubation at room temperature...
Introduction Pakistan's private sector caters to around 65% of family planning users. Private was promoted in the Delivering Accelerated Family Planning Pakistan (DAFPAK) program by UK's Foreign, Commonwealth & Development Office (FCDO) 2019. We use data from DAFPAK analyze clientele and products distributed two major NGOs, Marie Stopes Society (MSS) DKT Pakistan, that support providers Pakistan. also examined effect COVID-19 on client visits contraceptives uptake at facilities...
Energy poverty in the rural areas of third world countries is an important factor that stifles human development. Rural electrification considered a viable solution to improve socio-economic status and living standard for communities suffering from intermittent grid electricity. Designing microgrid architectures with optimal planning essential providing electricity access. Pakistan extreme shortage electricity, resulting severe load shedding. China-Pakistan Economic Corridor (CPEC) involves...