- Acute Ischemic Stroke Management
- Venous Thromboembolism Diagnosis and Management
- Cerebrovascular and Carotid Artery Diseases
- Stroke Rehabilitation and Recovery
- Traumatic Brain Injury and Neurovascular Disturbances
- Colorectal Cancer Surgical Treatments
- Gastric Cancer Management and Outcomes
- Inflammatory Bowel Disease
- Diverticular Disease and Complications
- Pelvic floor disorders treatments
- Microscopic Colitis
- Cardiac, Anesthesia and Surgical Outcomes
- Colorectal and Anal Carcinomas
- Pelvic and Acetabular Injuries
- Colorectal Cancer Screening and Detection
- Hernia repair and management
- Innovations in Medical Education
- Autoimmune and Inflammatory Disorders
- Medical Education and Admissions
- Peripheral Neuropathies and Disorders
- Gun Ownership and Violence Research
- Healthcare cost, quality, practices
- Photoacoustic and Ultrasonic Imaging
- CNS Lymphoma Diagnosis and Treatment
- Blood Pressure and Hypertension Studies
Monash Health
2024-2025
The University of Melbourne
2022-2025
The Royal Melbourne Hospital
2022-2025
Cleveland Clinic
2022-2025
Parks Victoria
2025
Monash University
2012-2024
Florey Institute of Neuroscience and Mental Health
2024
Children's Hospital of Orange County
2023
University of Arizona
2023
Ambulance Victoria
2022
BACKGROUND: Vascular territory mapping (VTM) software estimates which intracerebral vessel provides predominant arterial flow to a brain voxel. The presence of antegrade in the setting acute middle cerebral artery (MCA) occlusion is associated with improved outcomes. We identify whether VTM determinant patients proximal MCA occlusion. METHODS: Consecutive first branch (M1) were analyzed from International Stroke Perfusion Imaging Registry their computed tomography perfusion reprocessed...
Vascular territory mapping (VTM) software estimates which intracerebral vessel provides peak arterial flow to a brain voxel. This observational study was performed assess the hypothesis that VTM algorithm may correlate visual measurements of leptomeningeal grading and stroke outcome measures in acute middle cerebral artery (MCA) occlusion. assigned regions an estimated feeding vessel. Whole dynamic CT angiography used visually grade extent either anterior or posterior arteries. The final...
Abstract Background Injuries, the leading cause of death in children 1–17 years old, are often preventable. Injury patterns impacted by changes child’s environment, shifts supervision, and caregiver stressors. The objective this study was to evaluate incidence proportion injuries, mechanisms, severity seen Pediatric Emergency Departments (PEDs) during COVID-19 pandemic. Methods This multicenter, cross-sectional from January 2019 through December 2020 examined visits 40 PEDs for < 18 old....
BACKGROUND: Total neoadjuvant therapy in treatment of stage II-III rectal cancer involves administration either induction or consolidation chemotherapy with chemoradiation before surgery. is associated increased complete response rate, which defined as the proportion patients who had pathological after surgery sustained clinical at least for a year under surveillance. OBJECTIVE: To identify predictors to total and compare different diagnostic tools predicting response. DESIGN: Retrospective...
Background Mobile stroke units have been shown to deliver faster patient care and improve clinical outcomes. However, costs associated with staffing limit their use densely populated cities. Using the Melbourne mobile unit, we aim evaluate safety, timeliness, resource efficiency of a telemedicine model, where neurologist assesses remotely, via telemedicine, compared an onboard model. We hypothesize that, without compromising model will provide timely superior efficiency. Methods prospective,...
Patients undergoing colorectal surgery for inflammatory bowel disease (IBD) are recognized to have an increased risk of venous thromboembolism (VTE). The aim this study was determine the perioperative factors VTE and create a predictive scoring system in IBD cohort.The NSQIP-IBD Collaboration Registry from 2017 2020 used identify patients. Demographics, operative outcomes data patients surgeries were analysed. A logistic multivariate regression model performed using all significant variables...
Mobile stroke units (MSUs) equipped with a CT scanner are increasingly being used to assess and treat patients' prehospital thrombolysis transfer them the most appropriate hospital for ongoing care thrombectomy when indicated. The effect of MSUs in both reducing time reperfusion treatment improving patient outcomes is now established. There an opportunity improve efficacy provided by MSU. Tenecteplase potent plasminogen activator, which may have benefits over standard lytic alteplase....
We present an annotated dataset for the purposes of creating a benchmark in Artificial Intelligence automated clot detection. While there are commercial tools available detection on computed tomographic (CT) angiographs, they have not been compared standardized manner whereby accuracy is reported publicly dataset. Furthermore, known difficulties - namely, cases where robust collateral flow, or residual flow and occlusions smaller vessels it necessary to drive initiative overcome these...
BACKGROUND: Patients with Crohn’s disease face an elevated risk of colorectal cancer, in part due to underlying chronic inflammation. Biologic therapy is the mainstay medical treatment; however, impact treatment on cancer–related outcomes remains unclear. OBJECTIVE: To investigate association between prior exposure biologic and patients disease. DESIGN: Retrospective cohort study. SETTINGS: High volume, tertiary surgery department. PATIENTS: Adults (older than 18 years) diagnosed cancer who...
Among rectal cancer patients treated with Total Neoadjuvant Therapy, it is unclear whether early, post-induction restaging associated final tumor response. If so, interim may alter decision-making.
Clinical and imaging characteristics of patients receiving direct oral anticoagulants presenting with transient ischaemic attack or stroke are lacking. A retrospective review all who presented to a high-volume primary centre acute symptoms while prescribed an anticoagulant between January 2012 June 2017. Clinical, radiological functional outcomes were examined. Anticoagulated diagnosed shared similar disease outcome irrespective used. One-third warfarin sub-therapeutic international...
This descriptive study explores typical patterns of vascular territory mapping (VTM) in ischaemic stroke patients with proximal vessel occlusion. VTM is a novel process using CT perfusion that can identify the source and extent collateral blood flow It functions by determining which provides dominant to brain voxel.A total 167 consecutive were analysed from INSPIRE (International Stroke Perfusion Imaging Registry) their reprocessed through software. We explored maps generated this software...