A5101690917- Advanced biosensing and bioanalysis techniques
- Molecular Sensors and Ion Detection
- Analytical Chemistry and Sensors
- Electrochemical Analysis and Applications
- Electrochemical sensors and biosensors
- Gold and Silver Nanoparticles Synthesis and Applications
- Luminescence and Fluorescent Materials
- Advanced NMR Techniques and Applications
- CO2 Reduction Techniques and Catalysts
- Electrocatalysts for Energy Conversion
- Advanced Computational Techniques and Applications
- Electron Spin Resonance Studies
- Geographic Information Systems Studies
- Educational Technology and Pedagogy
- Protein Structure and Dynamics
- Identification and Quantification in Food
- Ionic liquids properties and applications
- Coenzyme Q10 studies and effects
- Nanomaterials for catalytic reactions
- Microbial bioremediation and biosurfactants
- Bioactive Compounds and Antitumor Agents
- Innovative Educational Techniques
- Ubiquitin and proteasome pathways
- Calcium Carbonate Crystallization and Inhibition
- Medicinal Plant Pharmacodynamics Research
National Institute on Drug Abuse
2022-2025
University of Baltimore
2025
National Institutes of Health
2024
Thermo Fisher Scientific (China)
2023-2024
East China University of Science and Technology
2011-2022
Land Consolidation and Rehabilitation Center
2022
Shaanxi Provincial Land Engineering Construction Group
2022
China Land Surveying and Planning Institute
2022
Ministry of Natural Resources
2022
Sichuan University
2020
A method based on plasmon resonance Rayleigh scattering (PRRS) spectroscopy and dark-field microscopy (DFM) was established for the real-time monitoring of a click reaction at single-nanoparticle level. Click reactions surface single gold nanoparticles (GNPs) result in interparticle coupling, which leads to red-shift λmax (Δλmax=43 nm) PRRS spectra color change DFM (from green orange). As service our authors readers, this journal provides supporting information supplied by authors. Such...
A green fluorescent protein chromophore inspired chemosenor for Zn2+ was designed and synthesized. specific fluorescence enhancement observed due to restricted rotation between the 1,10-phenanthroline imidazolone moieties.
Abstract Background Sigma-1 receptor (S1R) is a calcium-sensitive, ligand-operated chaperone protein present on the endoplasmic reticulum (ER) membrane and more specifically at mitochondria- associated (MAM)[1, 2]. At MAM, S1R plays an important role in ER- mitochondrial inter-organelle calcium signaling cell survival[3, 4]. Moreover, its agonists confer resilience against various neurodegenerative diseases[5-8]. resting state, either monomeric or oligomeric state but ratio of these...
Abstract Scattering recovered plasmonic resonance energy transfer (SR-PRET) was reported by blocking the plasmon (PRET) from gold nanoparticle (GNP) to adsorbed molecules (RdBS). Due selective cleavage of Si-O bond F − ions, quenching is switched off causing an increase in brightness GNPs,detected using dark-field microscopy (DFM) were brightened. This method successfully applied determination fluoride ions water. The SR-PRET provides a potential approach for vitro/vivo sensing with high...
Eine Kombination aus Plasmonenresonanz-Rayleigh-Streuung (PRRS) und Dunkelfeldmikroskopie (DFM) ermöglicht die Verfolgung einer Klick-Reaktion auf Nanopartikelebene in Echtzeit. Klick-Reaktionen der Oberfläche einzelner Goldnanopartikel (GNPs) führen zur Partikel-Partikel-Kupplung diese wiederum zu Rotverschiebung von λmax (Δλmax=43 nm) den PRRS-Spektren sowie einem Farbwechsel GNPs im DFM (von Grün nach Orange).
Selective electrochemical reduction of CO2 by using renewable electricity has received considerable attention because the potential to convert a harmful greenhouse gas into useful chemicals. A high-performance electrocatalyst for is constructed based on metal nanoparticles/organic molecule hybrid materials. On nanoscale, Au nanoparticles are uniformly anchored carbon nanotubes afford substantially increased current density, improved selectivity CO, and enhanced stability. molecular level,...
A portable analysis system has been successfully developed for on-site heavy metal ion detection in the environment. The disposable Au nanoparticles (AuNPs) amalgam modified screen-printed carbon electrodes (SPCE) are used this monitoring of Cd <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2+</sup> real water samples. response current is linear to concentration within range 8.4 ppb 500 ppm, with a low limit 2.6 ppb. Meanwhile, surfaces SPCE...
Plasmon resonance energy transfer (PRET) has been widely applied in the detection of bio-recognition, heavy metal ions and cellular reactions with high sensitivity, based on overlap between plasmon scattering band nanoparticles absorption surface-modified chromophore molecules. Previous sensors PRET were all implemented gold nanospheres light range 530 to 600 nm. In this work, a PRET-based nanosensor was developed thiol-di(2-picolyl)amine-modified single nanorod for Cu(2+) aqueous solution...
We report molecular dynamics simulations in the explicit membrane environment of a small membrane-embedded protein, sarcolipin, which regulates sarcoplasmic reticulum Ca-ATPase activity both cardiac and skeletal muscle. In its monomeric form, we found that sarcolipin adopts helical conformation, with computed average tilt angle 28 ± 6° azymuthal angles 66 22°, reasonable accord determined experimentally (23 2° 50 4°, respectively) using solid-state NMR separated-local-field experiments. The...
We have developed an efficient and green cross-coupling reaction for alkoxylation of the primary benzylic C(sp 3 )–H bond. KO t Bu was used as a catalyst O 2 sole oxidant in methoxylation C–H
With the growing popularity of modularity in software development comes rise package managers and language ecosystems. Among them, npm stands out as most extensive manager, hosting more than 2 million third-party open-source packages that greatly simplify process building code. However, this openness also brings security risks, evidenced by numerous poisoning incidents. In paper, we synchronize a local cache containing 3.4 near real-time to give us access code details. Further, perform...
Residual dipolar couplings (RDCs) are widely used as orientation-dependent NMR restraints to improve the resolution of conformational ensemble biomacromolecules and define relative orientation multidomain proteins protein complexes. However, interpretation RDCs is complicated by intrinsic degeneracy analytical solutions dynamics that lead ill-defined orientations structural domains (ghost orientations). Here, we illustrate how from paramagnetic relaxation enhancement (PRE) experiments lift...
A novel type of ion-selective electrode (ISE) was manufactured for detecting trace amounts Cu(II) ions. The basic substrates ISE were fabricated using screen-printing technology, which could produce disposable electrodes on a large-scale with good repeatability. Moreover, the printed integrated three-electrode system be directly used to read out open-circuit potentials by handheld device through USB port. film composed gold nanorods (GNRs) and 6-(bis(pyridin-2-ylmethyl)amino)hexane-1-thiol...
A GFP chromophore inspired fluorescent chemodosimeter was synthesized, which exhibited "naked-eye" detection for F− with high selectivity and sensitivity based on promoted cleavage of silicon–oxygen bonds the deprotonation reaction via hydrogen-bonding interactions.